Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion
Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1994 |
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| Umfang: |
4 |
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| Reproduktion: |
Springer Online Journal Archives 1860-2002 |
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| Übergeordnetes Werk: |
in: Clinical autonomic research - 1991, 4(1994) vom: Juni, Seite 319-322 |
| Übergeordnetes Werk: |
volume:4 ; year:1994 ; month:06 ; pages:319-322 ; extent:4 |
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NLEJ209049413 |
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| 245 | 1 | 0 | |a Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion |
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| 520 | |a Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. | ||
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| 700 | 1 | |a Kumazawa, Kazuhiko |4 oth | |
| 700 | 1 | |a Sobue, Gen |4 oth | |
| 700 | 1 | |a Mitsuma, Terunori |4 oth | |
| 700 | 1 | |a Ogawa, Tokuo |4 oth | |
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(DE-627)NLEJ209049413 DE-627 ger DE-627 rakwb eng Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion 1994 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. Springer Online Journal Archives 1860-2002 Kumazawa, Kazuhiko oth Sobue, Gen oth Mitsuma, Terunori oth Ogawa, Tokuo oth in Clinical autonomic research 1991 4(1994) vom: Juni, Seite 319-322 (DE-627)NLEJ188988114 (DE-600)2081578-5 1619-1560 nnns volume:4 year:1994 month:06 pages:319-322 extent:4 http://dx.doi.org/10.1007/BF01821532 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 4 1994 6 319-322 4 |
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(DE-627)NLEJ209049413 DE-627 ger DE-627 rakwb eng Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion 1994 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. Springer Online Journal Archives 1860-2002 Kumazawa, Kazuhiko oth Sobue, Gen oth Mitsuma, Terunori oth Ogawa, Tokuo oth in Clinical autonomic research 1991 4(1994) vom: Juni, Seite 319-322 (DE-627)NLEJ188988114 (DE-600)2081578-5 1619-1560 nnns volume:4 year:1994 month:06 pages:319-322 extent:4 http://dx.doi.org/10.1007/BF01821532 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 4 1994 6 319-322 4 |
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(DE-627)NLEJ209049413 DE-627 ger DE-627 rakwb eng Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion 1994 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. Springer Online Journal Archives 1860-2002 Kumazawa, Kazuhiko oth Sobue, Gen oth Mitsuma, Terunori oth Ogawa, Tokuo oth in Clinical autonomic research 1991 4(1994) vom: Juni, Seite 319-322 (DE-627)NLEJ188988114 (DE-600)2081578-5 1619-1560 nnns volume:4 year:1994 month:06 pages:319-322 extent:4 http://dx.doi.org/10.1007/BF01821532 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 4 1994 6 319-322 4 |
| allfieldsGer |
(DE-627)NLEJ209049413 DE-627 ger DE-627 rakwb eng Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion 1994 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. Springer Online Journal Archives 1860-2002 Kumazawa, Kazuhiko oth Sobue, Gen oth Mitsuma, Terunori oth Ogawa, Tokuo oth in Clinical autonomic research 1991 4(1994) vom: Juni, Seite 319-322 (DE-627)NLEJ188988114 (DE-600)2081578-5 1619-1560 nnns volume:4 year:1994 month:06 pages:319-322 extent:4 http://dx.doi.org/10.1007/BF01821532 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 4 1994 6 319-322 4 |
| allfieldsSound |
(DE-627)NLEJ209049413 DE-627 ger DE-627 rakwb eng Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion 1994 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. Springer Online Journal Archives 1860-2002 Kumazawa, Kazuhiko oth Sobue, Gen oth Mitsuma, Terunori oth Ogawa, Tokuo oth in Clinical autonomic research 1991 4(1994) vom: Juni, Seite 319-322 (DE-627)NLEJ188988114 (DE-600)2081578-5 1619-1560 nnns volume:4 year:1994 month:06 pages:319-322 extent:4 http://dx.doi.org/10.1007/BF01821532 GBV_USEFLAG_U ZDB-1-SOJ GBV_NL_ARTICLE AR 4 1994 6 319-322 4 |
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modulatory effects of calcitonin gene-related peptide and substance p on human cholinergic sweat secretion |
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Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion |
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Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. |
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Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. |
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Abstract Immunoreacttvtty to various peptides has been demonstrated in nerve terminals around the sweat glands, suggesting a regulatory function for these peptides on sweating. The present study evaluated the calcitonin-gene related peptide and substance P related regulation of sweating in man. Both calcitonin-gene related peptide and substance P, when administered alone, failed to cause sweat secretion, whereas sweating induced by methacholine chloride alone was four times greater when administered with calcitonin-gene related peptide and suppressed by 70% when administered with substance P. The degree of calcitonin-gene related peptide dependent augmentation and substance P dependent suppression of the methacholine chloride induced sweating was dependent on the concentration of calcitonin-gene related peptide and substance P. These findings suggest that calcitonin-gene related peptide enhances cholinergic sweating and substance P inhibits it. |
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