A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds
A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population ba...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
The Berkeley Electronic Press ; 2003 |
|---|
| Schlagwörter: |
|---|
| Reproduktion: |
Berkeley Electronic Press Academic Journals |
|---|---|
| Übergeordnetes Werk: |
In: International journal of chemical reactor engineering - Berkeley, Calif. : Bepress, 2003, 1.2003, 1, A38 |
| Übergeordnetes Werk: |
volume:1 ; year:2003 ; number:1 ; pages:38 |
| Links: |
|---|
| Katalog-ID: |
NLEJ219556091 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ219556091 | ||
| 003 | DE-627 | ||
| 005 | 20230506181734.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 090716s2003 xxu|||||o 00| ||eng c | ||
| 035 | |a (DE-627)NLEJ219556091 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 044 | |c XD-US | ||
| 245 | 1 | 0 | |a A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds |
| 264 | 1 | |b The Berkeley Electronic Press |c 2003 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). | ||
| 533 | |f Berkeley Electronic Press Academic Journals | ||
| 650 | 4 | |a Modeling | |
| 650 | 4 | |a Tissue Engineering Cartilage Construct | |
| 650 | 4 | |a Population Balance | |
| 650 | 4 | |a Tissue Engineering | |
| 700 | 1 | |a Pisu, Massimo |4 oth | |
| 700 | 1 | |a Lai, Nicola |4 oth | |
| 700 | 1 | |a Cincotti, Alberto |4 oth | |
| 700 | 1 | |a Delogu, Francesco |4 oth | |
| 700 | 1 | |a Cao, Giacomo |4 oth | |
| 773 | 0 | 8 | |i In |t International journal of chemical reactor engineering |d Berkeley, Calif. : Bepress, 2003 |g 1.2003, 1, A38 |h Online-Ressource |w (DE-627)NLEJ219537194 |w (DE-600)2112754-2 |x 1542-6580 |7 nnns |
| 773 | 1 | 8 | |g volume:1 |g year:2003 |g number:1 |g pages:38 |
| 856 | 4 | 0 | |u http://www.bepress.com/ijcre/vol1/A38 |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a ZDB-1-BEP | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 1 |j 2003 |e 1 |h 38 |y 1.2003, 1, A38 | ||
| matchkey_str |
article:15426580:2003----::smltomdloterwhfnierdatlgo |
|---|---|
| hierarchy_sort_str |
2003 |
| publishDate |
2003 |
| allfields |
(DE-627)NLEJ219556091 DE-627 ger DE-627 rakwb eng XD-US A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds The Berkeley Electronic Press 2003 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). Berkeley Electronic Press Academic Journals Modeling Tissue Engineering Cartilage Construct Population Balance Tissue Engineering Pisu, Massimo oth Lai, Nicola oth Cincotti, Alberto oth Delogu, Francesco oth Cao, Giacomo oth In International journal of chemical reactor engineering Berkeley, Calif. : Bepress, 2003 1.2003, 1, A38 Online-Ressource (DE-627)NLEJ219537194 (DE-600)2112754-2 1542-6580 nnns volume:1 year:2003 number:1 pages:38 http://www.bepress.com/ijcre/vol1/A38 GBV_USEFLAG_U ZDB-1-BEP GBV_NL_ARTICLE AR 1 2003 1 38 1.2003, 1, A38 |
| spelling |
(DE-627)NLEJ219556091 DE-627 ger DE-627 rakwb eng XD-US A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds The Berkeley Electronic Press 2003 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). Berkeley Electronic Press Academic Journals Modeling Tissue Engineering Cartilage Construct Population Balance Tissue Engineering Pisu, Massimo oth Lai, Nicola oth Cincotti, Alberto oth Delogu, Francesco oth Cao, Giacomo oth In International journal of chemical reactor engineering Berkeley, Calif. : Bepress, 2003 1.2003, 1, A38 Online-Ressource (DE-627)NLEJ219537194 (DE-600)2112754-2 1542-6580 nnns volume:1 year:2003 number:1 pages:38 http://www.bepress.com/ijcre/vol1/A38 GBV_USEFLAG_U ZDB-1-BEP GBV_NL_ARTICLE AR 1 2003 1 38 1.2003, 1, A38 |
| allfields_unstemmed |
(DE-627)NLEJ219556091 DE-627 ger DE-627 rakwb eng XD-US A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds The Berkeley Electronic Press 2003 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). Berkeley Electronic Press Academic Journals Modeling Tissue Engineering Cartilage Construct Population Balance Tissue Engineering Pisu, Massimo oth Lai, Nicola oth Cincotti, Alberto oth Delogu, Francesco oth Cao, Giacomo oth In International journal of chemical reactor engineering Berkeley, Calif. : Bepress, 2003 1.2003, 1, A38 Online-Ressource (DE-627)NLEJ219537194 (DE-600)2112754-2 1542-6580 nnns volume:1 year:2003 number:1 pages:38 http://www.bepress.com/ijcre/vol1/A38 GBV_USEFLAG_U ZDB-1-BEP GBV_NL_ARTICLE AR 1 2003 1 38 1.2003, 1, A38 |
| allfieldsGer |
(DE-627)NLEJ219556091 DE-627 ger DE-627 rakwb eng XD-US A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds The Berkeley Electronic Press 2003 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). Berkeley Electronic Press Academic Journals Modeling Tissue Engineering Cartilage Construct Population Balance Tissue Engineering Pisu, Massimo oth Lai, Nicola oth Cincotti, Alberto oth Delogu, Francesco oth Cao, Giacomo oth In International journal of chemical reactor engineering Berkeley, Calif. : Bepress, 2003 1.2003, 1, A38 Online-Ressource (DE-627)NLEJ219537194 (DE-600)2112754-2 1542-6580 nnns volume:1 year:2003 number:1 pages:38 http://www.bepress.com/ijcre/vol1/A38 GBV_USEFLAG_U ZDB-1-BEP GBV_NL_ARTICLE AR 1 2003 1 38 1.2003, 1, A38 |
| allfieldsSound |
(DE-627)NLEJ219556091 DE-627 ger DE-627 rakwb eng XD-US A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds The Berkeley Electronic Press 2003 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). Berkeley Electronic Press Academic Journals Modeling Tissue Engineering Cartilage Construct Population Balance Tissue Engineering Pisu, Massimo oth Lai, Nicola oth Cincotti, Alberto oth Delogu, Francesco oth Cao, Giacomo oth In International journal of chemical reactor engineering Berkeley, Calif. : Bepress, 2003 1.2003, 1, A38 Online-Ressource (DE-627)NLEJ219537194 (DE-600)2112754-2 1542-6580 nnns volume:1 year:2003 number:1 pages:38 http://www.bepress.com/ijcre/vol1/A38 GBV_USEFLAG_U ZDB-1-BEP GBV_NL_ARTICLE AR 1 2003 1 38 1.2003, 1, A38 |
| language |
English |
| source |
In International journal of chemical reactor engineering 1.2003, 1, A38 volume:1 year:2003 number:1 pages:38 |
| sourceStr |
In International journal of chemical reactor engineering 1.2003, 1, A38 volume:1 year:2003 number:1 pages:38 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Modeling Tissue Engineering Cartilage Construct Population Balance Tissue Engineering |
| isfreeaccess_bool |
false |
| container_title |
International journal of chemical reactor engineering |
| authorswithroles_txt_mv |
Pisu, Massimo @@oth@@ Lai, Nicola @@oth@@ Cincotti, Alberto @@oth@@ Delogu, Francesco @@oth@@ Cao, Giacomo @@oth@@ |
| publishDateDaySort_date |
2003-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ219537194 |
| id |
NLEJ219556091 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ219556091</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506181734.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">090716s2003 xxu|||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ219556091</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="c">XD-US</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="b">The Berkeley Electronic Press</subfield><subfield code="c">2003</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg).</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Berkeley Electronic Press Academic Journals</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Modeling</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Tissue Engineering Cartilage Construct</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Population Balance</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Tissue Engineering</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pisu, Massimo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lai, Nicola</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cincotti, Alberto</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Delogu, Francesco</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cao, Giacomo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">International journal of chemical reactor engineering</subfield><subfield code="d">Berkeley, Calif. : Bepress, 2003</subfield><subfield code="g">1.2003, 1, A38</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ219537194</subfield><subfield code="w">(DE-600)2112754-2</subfield><subfield code="x">1542-6580</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:1</subfield><subfield code="g">year:2003</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:38</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.bepress.com/ijcre/vol1/A38</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-BEP</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">1</subfield><subfield code="j">2003</subfield><subfield code="e">1</subfield><subfield code="h">38</subfield><subfield code="y">1.2003, 1, A38</subfield></datafield></record></collection>
|
| series2 |
Berkeley Electronic Press Academic Journals |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ219537194 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| collection |
NL |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1542-6580 |
| topic_title |
A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds Modeling Tissue Engineering Cartilage Construct Population Balance Tissue Engineering |
| publisher |
The Berkeley Electronic Press |
| publisherStr |
The Berkeley Electronic Press |
| topic |
misc Modeling misc Tissue Engineering Cartilage Construct misc Population Balance misc Tissue Engineering |
| spellingShingle |
misc Modeling misc Tissue Engineering Cartilage Construct misc Population Balance misc Tissue Engineering A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds |
| topic_unstemmed |
misc Modeling misc Tissue Engineering Cartilage Construct misc Population Balance misc Tissue Engineering |
| topic_browse |
misc Modeling misc Tissue Engineering Cartilage Construct misc Population Balance misc Tissue Engineering |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
m p mp n l nl a c ac f d fd g c gc |
| hierarchy_parent_title |
International journal of chemical reactor engineering |
| hierarchy_parent_id |
NLEJ219537194 |
| hierarchy_top_title |
International journal of chemical reactor engineering |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ219537194 (DE-600)2112754-2 |
| title |
A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds |
| ctrlnum |
(DE-627)NLEJ219556091 |
| title_full |
A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds |
| journal |
International journal of chemical reactor engineering |
| journalStr |
International journal of chemical reactor engineering |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2003 |
| contenttype_str_mv |
zzz |
| container_start_page |
38 |
| container_volume |
1 |
| format_se |
Elektronische Aufsätze |
| countryofpublication_str_mv |
XD-US |
| title_sort |
a simulation model for the growth of engineered cartilage on polymeric scaffolds |
| title_auth |
A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds |
| abstract |
A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). |
| abstractGer |
A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). |
| abstract_unstemmed |
A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg). |
| collection_details |
GBV_USEFLAG_U ZDB-1-BEP GBV_NL_ARTICLE |
| container_issue |
1 |
| title_short |
A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds |
| url |
http://www.bepress.com/ijcre/vol1/A38 |
| remote_bool |
true |
| author2 |
Pisu, Massimo Lai, Nicola Cincotti, Alberto Delogu, Francesco Cao, Giacomo |
| author2Str |
Pisu, Massimo Lai, Nicola Cincotti, Alberto Delogu, Francesco Cao, Giacomo |
| ppnlink |
NLEJ219537194 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth |
| up_date |
2024-07-06T05:29:12.241Z |
| _version_ |
1803806312749858817 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ219556091</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506181734.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">090716s2003 xxu|||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ219556091</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="c">XD-US</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">A Simulation Model for the Growth of Engineered Cartilage on Polymeric Scaffolds</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="b">The Berkeley Electronic Press</subfield><subfield code="c">2003</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">A mathematical model to simulate the growth of engineered cartilage on polymeric scaffold performed in rotating bioreactors has been developed. The model, based upon the material balance for the nutrient species (oxygen) and the primary extra-cellular matrix product (GAG), accounts for population balances to simulate cell proliferation and its distribution within the polymeric scaffold. A comparison between model results and literature experimental data in terms of GAG contents and its distribution within the tissue construct has been performed. All model parameters are taken from the literature except for the constant of the time rate of mass change appearing in the proposed population balance which has been adjusted to reproduce the experimental data concerning the tissue culture performed at 80 mm Hg of oxygen partial pressure. The predictive capability of the model has been also demonstrated by comparison with experimental data obtained for a different value of oxygen partial pressure (40 mm Hg).</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Berkeley Electronic Press Academic Journals</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Modeling</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Tissue Engineering Cartilage Construct</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Population Balance</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Tissue Engineering</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pisu, Massimo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lai, Nicola</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cincotti, Alberto</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Delogu, Francesco</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cao, Giacomo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">International journal of chemical reactor engineering</subfield><subfield code="d">Berkeley, Calif. : Bepress, 2003</subfield><subfield code="g">1.2003, 1, A38</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ219537194</subfield><subfield code="w">(DE-600)2112754-2</subfield><subfield code="x">1542-6580</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:1</subfield><subfield code="g">year:2003</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:38</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.bepress.com/ijcre/vol1/A38</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-BEP</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">1</subfield><subfield code="j">2003</subfield><subfield code="e">1</subfield><subfield code="h">38</subfield><subfield code="y">1.2003, 1, A38</subfield></datafield></record></collection>
|
| score |
7.397979 |