T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypo...
Ausführliche Beschreibung
Autor*in: |
Stephan, Matthias T [verfasserIn] Ponomarev, Vladimir [verfasserIn] Brentjens, Renier J [verfasserIn] |
---|
Format: |
E-Artikel |
---|---|
Sprache: |
Englisch |
Erschienen: |
s.l.: Nature Publishing Group ; 2007 |
---|
Umfang: |
10 |
---|
Reproduktion: |
Nature Archives 1869 - 2009 |
---|---|
Übergeordnetes Werk: |
In: Nature medicine - New York, NY : Nature America Inc., 1995, 13(2007), 12 vom: Jan., Seite 1440-1449 |
Übergeordnetes Werk: |
volume:13 ; year:2007 ; number:12 ; month:01 ; pages:1440-1449 ; extent:10 |
Links: |
---|
DOI / URN: |
10.1038/nm1676 |
---|
Katalog-ID: |
NLEJ231702361 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | NLEJ231702361 | ||
003 | DE-627 | ||
005 | 20230506150736.0 | ||
007 | cr uuu---uuuuu | ||
008 | 110224s2007 xxu|||||o 00| ||eng c | ||
024 | 7 | |a 10.1038/nm1676 |2 doi | |
035 | |a (DE-627)NLEJ231702361 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
044 | |c XD-US | ||
100 | 1 | |a Stephan, Matthias T |e verfasserin |4 aut | |
245 | 1 | 0 | |a T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
264 | 1 | |a [s.l.] |b Nature Publishing Group |c 2007 | |
300 | |a 10 | ||
336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
337 | |a nicht spezifiziert |b z |2 rdamedia | ||
338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
520 | |a [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... | ||
533 | |f Nature Archives 1869 - 2009 | ||
700 | 1 | |a Ponomarev, Vladimir |e verfasserin |4 aut | |
700 | 1 | |a Brentjens, Renier J |e verfasserin |4 aut | |
700 | 1 | |a Chang, Alex H |4 oth | |
700 | 1 | |a Dobrenkov, Konstantin V |4 oth | |
700 | 1 | |a Heller, Glenn |4 oth | |
700 | 1 | |a Sadelain, Michel |4 oth | |
773 | 0 | 8 | |i In |t Nature medicine |d New York, NY : Nature America Inc., 1995 |g 13(2007), 12 vom: Jan., Seite 1440-1449 |w (DE-627)NLEJ22768236X |w (DE-600)1484517-9 |x 1546-170X |7 nnns |
773 | 1 | 8 | |g volume:13 |g year:2007 |g number:12 |g month:01 |g pages:1440-1449 |g extent:10 |
856 | 4 | 0 | |u http://dx.doi.org/10.1038/nm1676 |q application/pdf |z Deutschlandweit zugänglich |
912 | |a GBV_USEFLAG_U | ||
912 | |a ZDB-1-NTA | ||
912 | |a GBV_NL_ARTICLE | ||
951 | |a AR | ||
952 | |d 13 |j 2007 |e 12 |c 1 |h 1440-1449 |g 10 |
author_variant |
m t s mt mts v p vp r j b rj rjb |
---|---|
matchkey_str |
article:1546170X:2007----::clecddd0n4blnueuontasotmltorsli |
hierarchy_sort_str |
2007 |
publishDate |
2007 |
allfields |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
spelling |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
allfields_unstemmed |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
allfieldsGer |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
allfieldsSound |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
language |
English |
source |
In Nature medicine 13(2007), 12 vom: Jan., Seite 1440-1449 volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 |
sourceStr |
In Nature medicine 13(2007), 12 vom: Jan., Seite 1440-1449 volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 |
format_phy_str_mv |
Article |
institution |
findex.gbv.de |
isfreeaccess_bool |
false |
container_title |
Nature medicine |
authorswithroles_txt_mv |
Stephan, Matthias T @@aut@@ Ponomarev, Vladimir @@aut@@ Brentjens, Renier J @@aut@@ Chang, Alex H @@oth@@ Dobrenkov, Konstantin V @@oth@@ Heller, Glenn @@oth@@ Sadelain, Michel @@oth@@ |
publishDateDaySort_date |
2007-01-01T00:00:00Z |
hierarchy_top_id |
NLEJ22768236X |
id |
NLEJ231702361 |
language_de |
englisch |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ231702361</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506150736.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">110224s2007 xxu|||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1038/nm1676</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ231702361</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="c">XD-US</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Stephan, Matthias T</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">[s.l.]</subfield><subfield code="b">Nature Publishing Group</subfield><subfield code="c">2007</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">10</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ...</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Nature Archives 1869 - 2009</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ponomarev, Vladimir</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brentjens, Renier J</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chang, Alex H</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dobrenkov, Konstantin V</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Heller, Glenn</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sadelain, Michel</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Nature medicine</subfield><subfield code="d">New York, NY : Nature America Inc., 1995</subfield><subfield code="g">13(2007), 12 vom: Jan., Seite 1440-1449</subfield><subfield code="w">(DE-627)NLEJ22768236X</subfield><subfield code="w">(DE-600)1484517-9</subfield><subfield code="x">1546-170X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:13</subfield><subfield code="g">year:2007</subfield><subfield code="g">number:12</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:1440-1449</subfield><subfield code="g">extent:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1038/nm1676</subfield><subfield code="q">application/pdf</subfield><subfield code="z">Deutschlandweit zugänglich</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-NTA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">13</subfield><subfield code="j">2007</subfield><subfield code="e">12</subfield><subfield code="c">1</subfield><subfield code="h">1440-1449</subfield><subfield code="g">10</subfield></datafield></record></collection>
|
series2 |
Nature Archives 1869 - 2009 |
author |
Stephan, Matthias T |
spellingShingle |
Stephan, Matthias T T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
authorStr |
Stephan, Matthias T |
ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ22768236X |
format |
electronic Article |
delete_txt_mv |
keep |
author_role |
aut aut aut |
collection |
NL |
publishPlace |
[s.l.] |
remote_str |
true |
illustrated |
Not Illustrated |
issn |
1546-170X |
topic_title |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
publisher |
Nature Publishing Group |
publisherStr |
Nature Publishing Group |
format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
format_main_str_mv |
Text Zeitschrift/Artikel |
carriertype_str_mv |
zu |
author2_variant |
a h c ah ahc k v d kv kvd g h gh m s ms |
hierarchy_parent_title |
Nature medicine |
hierarchy_parent_id |
NLEJ22768236X |
hierarchy_top_title |
Nature medicine |
isfreeaccess_txt |
false |
familylinks_str_mv |
(DE-627)NLEJ22768236X (DE-600)1484517-9 |
title |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
ctrlnum |
(DE-627)NLEJ231702361 |
title_full |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
author_sort |
Stephan, Matthias T |
journal |
Nature medicine |
journalStr |
Nature medicine |
lang_code |
eng |
isOA_bool |
false |
recordtype |
marc |
publishDateSort |
2007 |
contenttype_str_mv |
zzz |
container_start_page |
1440 |
author_browse |
Stephan, Matthias T Ponomarev, Vladimir Brentjens, Renier J |
container_volume |
13 |
physical |
10 |
format_se |
Elektronische Aufsätze |
countryofpublication_str_mv |
XD-US |
author-letter |
Stephan, Matthias T |
doi_str_mv |
10.1038/nm1676 |
author2-role |
verfasserin |
title_sort |
t cell–encoded cd80 and 4-1bbl induce auto- and transcostimulation, resulting in potent tumor rejection |
title_auth |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
abstract |
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... |
abstractGer |
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... |
abstract_unstemmed |
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... |
collection_details |
GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE |
container_issue |
12 |
title_short |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
url |
http://dx.doi.org/10.1038/nm1676 |
remote_bool |
true |
author2 |
Ponomarev, Vladimir Brentjens, Renier J Chang, Alex H Dobrenkov, Konstantin V Heller, Glenn Sadelain, Michel |
author2Str |
Ponomarev, Vladimir Brentjens, Renier J Chang, Alex H Dobrenkov, Konstantin V Heller, Glenn Sadelain, Michel |
ppnlink |
NLEJ22768236X |
mediatype_str_mv |
z |
isOA_txt |
false |
hochschulschrift_bool |
false |
author2_role |
oth oth oth oth |
doi_str |
10.1038/nm1676 |
up_date |
2024-07-05T23:34:50.819Z |
_version_ |
1803784018539315200 |
fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ231702361</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506150736.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">110224s2007 xxu|||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1038/nm1676</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ231702361</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="c">XD-US</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Stephan, Matthias T</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">[s.l.]</subfield><subfield code="b">Nature Publishing Group</subfield><subfield code="c">2007</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">10</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ...</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Nature Archives 1869 - 2009</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ponomarev, Vladimir</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brentjens, Renier J</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chang, Alex H</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dobrenkov, Konstantin V</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Heller, Glenn</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sadelain, Michel</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Nature medicine</subfield><subfield code="d">New York, NY : Nature America Inc., 1995</subfield><subfield code="g">13(2007), 12 vom: Jan., Seite 1440-1449</subfield><subfield code="w">(DE-627)NLEJ22768236X</subfield><subfield code="w">(DE-600)1484517-9</subfield><subfield code="x">1546-170X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:13</subfield><subfield code="g">year:2007</subfield><subfield code="g">number:12</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:1440-1449</subfield><subfield code="g">extent:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1038/nm1676</subfield><subfield code="q">application/pdf</subfield><subfield code="z">Deutschlandweit zugänglich</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-NTA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">13</subfield><subfield code="j">2007</subfield><subfield code="e">12</subfield><subfield code="c">1</subfield><subfield code="h">1440-1449</subfield><subfield code="g">10</subfield></datafield></record></collection>
|
score |
7.400386 |