T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypo...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Stephan, Matthias T [verfasserIn] Ponomarev, Vladimir [verfasserIn] Brentjens, Renier J [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
s.l.: Nature Publishing Group ; 2007 |
|---|
| Umfang: |
10 |
|---|
| Reproduktion: |
Nature Archives 1869 - 2009 |
|---|---|
| Übergeordnetes Werk: |
In: Nature medicine - New York, NY : Nature America Inc., 1995, 13(2007), 12 vom: Jan., Seite 1440-1449 |
| Übergeordnetes Werk: |
volume:13 ; year:2007 ; number:12 ; month:01 ; pages:1440-1449 ; extent:10 |
| Links: |
|---|
| DOI / URN: |
10.1038/nm1676 |
|---|
| Katalog-ID: |
NLEJ231702361 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ231702361 | ||
| 003 | DE-627 | ||
| 005 | 20230506150736.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 110224s2007 xxu|||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/nm1676 |2 doi | |
| 035 | |a (DE-627)NLEJ231702361 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 044 | |c XD-US | ||
| 100 | 1 | |a Stephan, Matthias T |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
| 264 | 1 | |a [s.l.] |b Nature Publishing Group |c 2007 | |
| 300 | |a 10 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... | ||
| 533 | |f Nature Archives 1869 - 2009 | ||
| 700 | 1 | |a Ponomarev, Vladimir |e verfasserin |4 aut | |
| 700 | 1 | |a Brentjens, Renier J |e verfasserin |4 aut | |
| 700 | 1 | |a Chang, Alex H |4 oth | |
| 700 | 1 | |a Dobrenkov, Konstantin V |4 oth | |
| 700 | 1 | |a Heller, Glenn |4 oth | |
| 700 | 1 | |a Sadelain, Michel |4 oth | |
| 773 | 0 | 8 | |i In |t Nature medicine |d New York, NY : Nature America Inc., 1995 |g 13(2007), 12 vom: Jan., Seite 1440-1449 |w (DE-627)NLEJ22768236X |w (DE-600)1484517-9 |x 1546-170X |7 nnns |
| 773 | 1 | 8 | |g volume:13 |g year:2007 |g number:12 |g month:01 |g pages:1440-1449 |g extent:10 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1038/nm1676 |q application/pdf |z Deutschlandweit zugänglich |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a ZDB-1-NTA | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 13 |j 2007 |e 12 |c 1 |h 1440-1449 |g 10 | ||
| author_variant |
m t s mt mts v p vp r j b rj rjb |
|---|---|
| matchkey_str |
article:1546170X:2007----::clecddd0n4blnueuontasotmltorsli |
| hierarchy_sort_str |
2007 |
| publishDate |
2007 |
| allfields |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
| spelling |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
| allfields_unstemmed |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
| allfieldsGer |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
| allfieldsSound |
10.1038/nm1676 doi (DE-627)NLEJ231702361 DE-627 ger DE-627 rakwb eng XD-US Stephan, Matthias T verfasserin aut T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection [s.l.] Nature Publishing Group 2007 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... Nature Archives 1869 - 2009 Ponomarev, Vladimir verfasserin aut Brentjens, Renier J verfasserin aut Chang, Alex H oth Dobrenkov, Konstantin V oth Heller, Glenn oth Sadelain, Michel oth In Nature medicine New York, NY : Nature America Inc., 1995 13(2007), 12 vom: Jan., Seite 1440-1449 (DE-627)NLEJ22768236X (DE-600)1484517-9 1546-170X nnns volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 http://dx.doi.org/10.1038/nm1676 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 13 2007 12 1 1440-1449 10 |
| language |
English |
| source |
In Nature medicine 13(2007), 12 vom: Jan., Seite 1440-1449 volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 |
| sourceStr |
In Nature medicine 13(2007), 12 vom: Jan., Seite 1440-1449 volume:13 year:2007 number:12 month:01 pages:1440-1449 extent:10 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| isfreeaccess_bool |
false |
| container_title |
Nature medicine |
| authorswithroles_txt_mv |
Stephan, Matthias T @@aut@@ Ponomarev, Vladimir @@aut@@ Brentjens, Renier J @@aut@@ Chang, Alex H @@oth@@ Dobrenkov, Konstantin V @@oth@@ Heller, Glenn @@oth@@ Sadelain, Michel @@oth@@ |
| publishDateDaySort_date |
2007-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ22768236X |
| id |
NLEJ231702361 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ231702361</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506150736.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">110224s2007 xxu|||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1038/nm1676</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ231702361</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="c">XD-US</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Stephan, Matthias T</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">[s.l.]</subfield><subfield code="b">Nature Publishing Group</subfield><subfield code="c">2007</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">10</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ...</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Nature Archives 1869 - 2009</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ponomarev, Vladimir</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brentjens, Renier J</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chang, Alex H</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dobrenkov, Konstantin V</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Heller, Glenn</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sadelain, Michel</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Nature medicine</subfield><subfield code="d">New York, NY : Nature America Inc., 1995</subfield><subfield code="g">13(2007), 12 vom: Jan., Seite 1440-1449</subfield><subfield code="w">(DE-627)NLEJ22768236X</subfield><subfield code="w">(DE-600)1484517-9</subfield><subfield code="x">1546-170X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:13</subfield><subfield code="g">year:2007</subfield><subfield code="g">number:12</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:1440-1449</subfield><subfield code="g">extent:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1038/nm1676</subfield><subfield code="q">application/pdf</subfield><subfield code="z">Deutschlandweit zugänglich</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-NTA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">13</subfield><subfield code="j">2007</subfield><subfield code="e">12</subfield><subfield code="c">1</subfield><subfield code="h">1440-1449</subfield><subfield code="g">10</subfield></datafield></record></collection>
|
| series2 |
Nature Archives 1869 - 2009 |
| author |
Stephan, Matthias T |
| spellingShingle |
Stephan, Matthias T T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
| authorStr |
Stephan, Matthias T |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ22768236X |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut |
| collection |
NL |
| publishPlace |
[s.l.] |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1546-170X |
| topic_title |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
| publisher |
Nature Publishing Group |
| publisherStr |
Nature Publishing Group |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
a h c ah ahc k v d kv kvd g h gh m s ms |
| hierarchy_parent_title |
Nature medicine |
| hierarchy_parent_id |
NLEJ22768236X |
| hierarchy_top_title |
Nature medicine |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ22768236X (DE-600)1484517-9 |
| title |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
| ctrlnum |
(DE-627)NLEJ231702361 |
| title_full |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
| author_sort |
Stephan, Matthias T |
| journal |
Nature medicine |
| journalStr |
Nature medicine |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2007 |
| contenttype_str_mv |
zzz |
| container_start_page |
1440 |
| author_browse |
Stephan, Matthias T Ponomarev, Vladimir Brentjens, Renier J |
| container_volume |
13 |
| physical |
10 |
| format_se |
Elektronische Aufsätze |
| countryofpublication_str_mv |
XD-US |
| author-letter |
Stephan, Matthias T |
| doi_str_mv |
10.1038/nm1676 |
| author2-role |
verfasserin |
| title_sort |
t cell–encoded cd80 and 4-1bbl induce auto- and transcostimulation, resulting in potent tumor rejection |
| title_auth |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
| abstract |
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... |
| abstractGer |
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... |
| abstract_unstemmed |
[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ... |
| collection_details |
GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE |
| container_issue |
12 |
| title_short |
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection |
| url |
http://dx.doi.org/10.1038/nm1676 |
| remote_bool |
true |
| author2 |
Ponomarev, Vladimir Brentjens, Renier J Chang, Alex H Dobrenkov, Konstantin V Heller, Glenn Sadelain, Michel |
| author2Str |
Ponomarev, Vladimir Brentjens, Renier J Chang, Alex H Dobrenkov, Konstantin V Heller, Glenn Sadelain, Michel |
| ppnlink |
NLEJ22768236X |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth |
| doi_str |
10.1038/nm1676 |
| up_date |
2024-07-05T23:34:50.819Z |
| _version_ |
1803784018539315200 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ231702361</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506150736.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">110224s2007 xxu|||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1038/nm1676</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ231702361</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="c">XD-US</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Stephan, Matthias T</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">[s.l.]</subfield><subfield code="b">Nature Publishing Group</subfield><subfield code="c">2007</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">10</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">[Auszug] To reject tumors, T cells must overcome poor tumor immunogenicity and an adverse tumor microenvironment. Providing agonistic costimulatory signals to tumor-infiltrating T cells to augment T cell function remains a challenge for the implementation of safe and effective immunotherapy. We hypothesized ...</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Nature Archives 1869 - 2009</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ponomarev, Vladimir</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brentjens, Renier J</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chang, Alex H</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dobrenkov, Konstantin V</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Heller, Glenn</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sadelain, Michel</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Nature medicine</subfield><subfield code="d">New York, NY : Nature America Inc., 1995</subfield><subfield code="g">13(2007), 12 vom: Jan., Seite 1440-1449</subfield><subfield code="w">(DE-627)NLEJ22768236X</subfield><subfield code="w">(DE-600)1484517-9</subfield><subfield code="x">1546-170X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:13</subfield><subfield code="g">year:2007</subfield><subfield code="g">number:12</subfield><subfield code="g">month:01</subfield><subfield code="g">pages:1440-1449</subfield><subfield code="g">extent:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1038/nm1676</subfield><subfield code="q">application/pdf</subfield><subfield code="z">Deutschlandweit zugänglich</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-NTA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">13</subfield><subfield code="j">2007</subfield><subfield code="e">12</subfield><subfield code="c">1</subfield><subfield code="h">1440-1449</subfield><subfield code="g">10</subfield></datafield></record></collection>
|
| score |
7.400386 |