Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia
[Auszug] We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold increase in MYB expression, and knockdown of MYB expression initiates T cell differentiation....
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s.l.: Nature Publishing Group ; 2007 |
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3 |
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| Reproduktion: |
Nature Archives 1869 - 2009 |
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| Übergeordnetes Werk: |
In: Nature genetics - New York, NY : Nature America, 1992, 39(2007), 5, Seite 593-595 |
| Übergeordnetes Werk: |
volume:39 ; year:2007 ; number:5 ; month:00 ; pages:593-595 ; extent:3 |
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| DOI / URN: |
10.1038/ng2025 |
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10.1038/ng2025 doi (DE-627)NLEJ231726635 DE-627 ger DE-627 rakwb eng XD-US Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia [s.l.] Nature Publishing Group 2007 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold increase in MYB expression, and knockdown of MYB expression initiates T cell differentiation. Our ... Nature Archives 1869 - 2009 Lahortiga, Idoya oth De Keersmaecker, Kim oth Van Vlierberghe, Pieter oth Graux, Carlos oth Cauwelier, Barbara oth Lambert, Frederic oth Mentens, Nicole oth Beverloo, H Berna oth Pieters, Rob oth Speleman, Frank oth Odero, Maria D oth Bauters, Marijke oth Froyen, Guy oth Marynen, Peter oth Vandenberghe, Peter oth Wlodarska, Iwona oth Meijerink, Jules P P oth Cools, Jan oth In Nature genetics New York, NY : Nature America, 1992 39(2007), 5, Seite 593-595 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:39 year:2007 number:5 month:00 pages:593-595 extent:3 http://dx.doi.org/10.1038/ng2025 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 39 2007 5 0 593-595 3 |
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10.1038/ng2025 doi (DE-627)NLEJ231726635 DE-627 ger DE-627 rakwb eng XD-US Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia [s.l.] Nature Publishing Group 2007 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold increase in MYB expression, and knockdown of MYB expression initiates T cell differentiation. Our ... Nature Archives 1869 - 2009 Lahortiga, Idoya oth De Keersmaecker, Kim oth Van Vlierberghe, Pieter oth Graux, Carlos oth Cauwelier, Barbara oth Lambert, Frederic oth Mentens, Nicole oth Beverloo, H Berna oth Pieters, Rob oth Speleman, Frank oth Odero, Maria D oth Bauters, Marijke oth Froyen, Guy oth Marynen, Peter oth Vandenberghe, Peter oth Wlodarska, Iwona oth Meijerink, Jules P P oth Cools, Jan oth In Nature genetics New York, NY : Nature America, 1992 39(2007), 5, Seite 593-595 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:39 year:2007 number:5 month:00 pages:593-595 extent:3 http://dx.doi.org/10.1038/ng2025 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 39 2007 5 0 593-595 3 |
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10.1038/ng2025 doi (DE-627)NLEJ231726635 DE-627 ger DE-627 rakwb eng XD-US Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia [s.l.] Nature Publishing Group 2007 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold increase in MYB expression, and knockdown of MYB expression initiates T cell differentiation. Our ... Nature Archives 1869 - 2009 Lahortiga, Idoya oth De Keersmaecker, Kim oth Van Vlierberghe, Pieter oth Graux, Carlos oth Cauwelier, Barbara oth Lambert, Frederic oth Mentens, Nicole oth Beverloo, H Berna oth Pieters, Rob oth Speleman, Frank oth Odero, Maria D oth Bauters, Marijke oth Froyen, Guy oth Marynen, Peter oth Vandenberghe, Peter oth Wlodarska, Iwona oth Meijerink, Jules P P oth Cools, Jan oth In Nature genetics New York, NY : Nature America, 1992 39(2007), 5, Seite 593-595 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:39 year:2007 number:5 month:00 pages:593-595 extent:3 http://dx.doi.org/10.1038/ng2025 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 39 2007 5 0 593-595 3 |
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10.1038/ng2025 doi (DE-627)NLEJ231726635 DE-627 ger DE-627 rakwb eng XD-US Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia [s.l.] Nature Publishing Group 2007 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold increase in MYB expression, and knockdown of MYB expression initiates T cell differentiation. Our ... Nature Archives 1869 - 2009 Lahortiga, Idoya oth De Keersmaecker, Kim oth Van Vlierberghe, Pieter oth Graux, Carlos oth Cauwelier, Barbara oth Lambert, Frederic oth Mentens, Nicole oth Beverloo, H Berna oth Pieters, Rob oth Speleman, Frank oth Odero, Maria D oth Bauters, Marijke oth Froyen, Guy oth Marynen, Peter oth Vandenberghe, Peter oth Wlodarska, Iwona oth Meijerink, Jules P P oth Cools, Jan oth In Nature genetics New York, NY : Nature America, 1992 39(2007), 5, Seite 593-595 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:39 year:2007 number:5 month:00 pages:593-595 extent:3 http://dx.doi.org/10.1038/ng2025 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 39 2007 5 0 593-595 3 |
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[Auszug] We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold increase in MYB expression, and knockdown of MYB expression initiates T cell differentiation. Our ... |
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