Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
[Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has hig...
Ausführliche Beschreibung
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E-Artikel |
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Englisch |
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s.l.: Nature Publishing Group ; 2005 |
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3 |
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Reproduktion: |
Nature Archives 1869 - 2009 |
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Übergeordnetes Werk: |
In: Nature genetics - New York, NY : Nature America, 1992, 37(2005), 12 vom: Jan., Seite 1317-1319 |
Übergeordnetes Werk: |
volume:37 ; year:2005 ; number:12 ; month:01 ; pages:1317-1319 ; extent:3 |
Links: |
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DOI / URN: |
10.1038/ng1673 |
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10.1038/ng1673 doi (DE-627)NLEJ231734719 DE-627 ger DE-627 rakwb eng XD-US Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant [s.l.] Nature Publishing Group 2005 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... Nature Archives 1869 - 2009 Vang, Torkel oth Congia, Mauro oth Macis, Maria Doloretta oth Musumeci, Lucia oth Orrú, Valeria oth Zavattari, Patrizia oth Nika, Konstantina oth Tautz, Lutz oth Taskén, Kjetil oth Cucca, Francesco oth Mustelin, Tomas oth Bottini, Nunzio oth In Nature genetics New York, NY : Nature America, 1992 37(2005), 12 vom: Jan., Seite 1317-1319 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:37 year:2005 number:12 month:01 pages:1317-1319 extent:3 http://dx.doi.org/10.1038/ng1673 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 37 2005 12 1 1317-1319 3 |
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10.1038/ng1673 doi (DE-627)NLEJ231734719 DE-627 ger DE-627 rakwb eng XD-US Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant [s.l.] Nature Publishing Group 2005 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... Nature Archives 1869 - 2009 Vang, Torkel oth Congia, Mauro oth Macis, Maria Doloretta oth Musumeci, Lucia oth Orrú, Valeria oth Zavattari, Patrizia oth Nika, Konstantina oth Tautz, Lutz oth Taskén, Kjetil oth Cucca, Francesco oth Mustelin, Tomas oth Bottini, Nunzio oth In Nature genetics New York, NY : Nature America, 1992 37(2005), 12 vom: Jan., Seite 1317-1319 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:37 year:2005 number:12 month:01 pages:1317-1319 extent:3 http://dx.doi.org/10.1038/ng1673 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 37 2005 12 1 1317-1319 3 |
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10.1038/ng1673 doi (DE-627)NLEJ231734719 DE-627 ger DE-627 rakwb eng XD-US Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant [s.l.] Nature Publishing Group 2005 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... Nature Archives 1869 - 2009 Vang, Torkel oth Congia, Mauro oth Macis, Maria Doloretta oth Musumeci, Lucia oth Orrú, Valeria oth Zavattari, Patrizia oth Nika, Konstantina oth Tautz, Lutz oth Taskén, Kjetil oth Cucca, Francesco oth Mustelin, Tomas oth Bottini, Nunzio oth In Nature genetics New York, NY : Nature America, 1992 37(2005), 12 vom: Jan., Seite 1317-1319 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:37 year:2005 number:12 month:01 pages:1317-1319 extent:3 http://dx.doi.org/10.1038/ng1673 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 37 2005 12 1 1317-1319 3 |
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10.1038/ng1673 doi (DE-627)NLEJ231734719 DE-627 ger DE-627 rakwb eng XD-US Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant [s.l.] Nature Publishing Group 2005 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... Nature Archives 1869 - 2009 Vang, Torkel oth Congia, Mauro oth Macis, Maria Doloretta oth Musumeci, Lucia oth Orrú, Valeria oth Zavattari, Patrizia oth Nika, Konstantina oth Tautz, Lutz oth Taskén, Kjetil oth Cucca, Francesco oth Mustelin, Tomas oth Bottini, Nunzio oth In Nature genetics New York, NY : Nature America, 1992 37(2005), 12 vom: Jan., Seite 1317-1319 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:37 year:2005 number:12 month:01 pages:1317-1319 extent:3 http://dx.doi.org/10.1038/ng1673 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 37 2005 12 1 1317-1319 3 |
allfieldsSound |
10.1038/ng1673 doi (DE-627)NLEJ231734719 DE-627 ger DE-627 rakwb eng XD-US Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant [s.l.] Nature Publishing Group 2005 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... Nature Archives 1869 - 2009 Vang, Torkel oth Congia, Mauro oth Macis, Maria Doloretta oth Musumeci, Lucia oth Orrú, Valeria oth Zavattari, Patrizia oth Nika, Konstantina oth Tautz, Lutz oth Taskén, Kjetil oth Cucca, Francesco oth Mustelin, Tomas oth Bottini, Nunzio oth In Nature genetics New York, NY : Nature America, 1992 37(2005), 12 vom: Jan., Seite 1317-1319 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:37 year:2005 number:12 month:01 pages:1317-1319 extent:3 http://dx.doi.org/10.1038/ng1673 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 37 2005 12 1 1317-1319 3 |
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[Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... |
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[Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... |
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[Auszug] A SNP in the gene PTPN22 is associated with type 1 diabetes, rheumatoid arthritis, lupus, Graves thyroiditis, Addison disease and other autoimmune disorders. T cells from carriers of the predisposing allele produce less interleukin-2 upon TCR stimulation, and the encoded phosphatase has higher ... |
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Vang, Torkel Congia, Mauro Macis, Maria Doloretta Musumeci, Lucia Orrú, Valeria Zavattari, Patrizia Nika, Konstantina Tautz, Lutz Taskén, Kjetil Cucca, Francesco Mustelin, Tomas Bottini, Nunzio |
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