Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
[Auszug] We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13–p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tum...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Kurose, Keisuke [verfasserIn] Gilley, Kristie [verfasserIn] Matsumoto, Satoshi [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
s.l.: Nature Publishing Group ; 2002 |
|---|
| Umfang: |
3 |
|---|
| Reproduktion: |
Nature Archives 1869 - 2009 |
|---|---|
| Übergeordnetes Werk: |
In: Nature genetics - New York, NY : Nature America, 1992, 32(2002), 3 vom: Jan., Seite 355-357 |
| Übergeordnetes Werk: |
volume:32 ; year:2002 ; number:3 ; month:01 ; pages:355-357 ; extent:3 |
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| DOI / URN: |
10.1038/ng1013 |
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| 245 | 1 | 0 | |a Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas |
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10.1038/ng1013 doi (DE-627)NLEJ231743351 DE-627 ger DE-627 rakwb eng XD-US Kurose, Keisuke verfasserin aut Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas [s.l.] Nature Publishing Group 2002 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13–p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tumor ... Nature Archives 1869 - 2009 Gilley, Kristie verfasserin aut Matsumoto, Satoshi verfasserin aut Watson, Peter H. oth Zhou, Xiao-Ping oth Eng, Charis oth In Nature genetics New York, NY : Nature America, 1992 32(2002), 3 vom: Jan., Seite 355-357 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:32 year:2002 number:3 month:01 pages:355-357 extent:3 http://dx.doi.org/10.1038/ng1013 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 32 2002 3 1 355-357 3 |
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10.1038/ng1013 doi (DE-627)NLEJ231743351 DE-627 ger DE-627 rakwb eng XD-US Kurose, Keisuke verfasserin aut Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas [s.l.] Nature Publishing Group 2002 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13–p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tumor ... Nature Archives 1869 - 2009 Gilley, Kristie verfasserin aut Matsumoto, Satoshi verfasserin aut Watson, Peter H. oth Zhou, Xiao-Ping oth Eng, Charis oth In Nature genetics New York, NY : Nature America, 1992 32(2002), 3 vom: Jan., Seite 355-357 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:32 year:2002 number:3 month:01 pages:355-357 extent:3 http://dx.doi.org/10.1038/ng1013 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 32 2002 3 1 355-357 3 |
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10.1038/ng1013 doi (DE-627)NLEJ231743351 DE-627 ger DE-627 rakwb eng XD-US Kurose, Keisuke verfasserin aut Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas [s.l.] Nature Publishing Group 2002 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13–p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tumor ... Nature Archives 1869 - 2009 Gilley, Kristie verfasserin aut Matsumoto, Satoshi verfasserin aut Watson, Peter H. oth Zhou, Xiao-Ping oth Eng, Charis oth In Nature genetics New York, NY : Nature America, 1992 32(2002), 3 vom: Jan., Seite 355-357 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:32 year:2002 number:3 month:01 pages:355-357 extent:3 http://dx.doi.org/10.1038/ng1013 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 32 2002 3 1 355-357 3 |
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10.1038/ng1013 doi (DE-627)NLEJ231743351 DE-627 ger DE-627 rakwb eng XD-US Kurose, Keisuke verfasserin aut Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas [s.l.] Nature Publishing Group 2002 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13–p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tumor ... Nature Archives 1869 - 2009 Gilley, Kristie verfasserin aut Matsumoto, Satoshi verfasserin aut Watson, Peter H. oth Zhou, Xiao-Ping oth Eng, Charis oth In Nature genetics New York, NY : Nature America, 1992 32(2002), 3 vom: Jan., Seite 355-357 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:32 year:2002 number:3 month:01 pages:355-357 extent:3 http://dx.doi.org/10.1038/ng1013 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 32 2002 3 1 355-357 3 |
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10.1038/ng1013 doi (DE-627)NLEJ231743351 DE-627 ger DE-627 rakwb eng XD-US Kurose, Keisuke verfasserin aut Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas [s.l.] Nature Publishing Group 2002 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13–p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tumor ... Nature Archives 1869 - 2009 Gilley, Kristie verfasserin aut Matsumoto, Satoshi verfasserin aut Watson, Peter H. oth Zhou, Xiao-Ping oth Eng, Charis oth In Nature genetics New York, NY : Nature America, 1992 32(2002), 3 vom: Jan., Seite 355-357 (DE-627)NLEJ227682351 (DE-600)1494946-5 1546-1718 nnns volume:32 year:2002 number:3 month:01 pages:355-357 extent:3 http://dx.doi.org/10.1038/ng1013 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 32 2002 3 1 355-357 3 |
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Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas |
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[Auszug] We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13–p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tumor ... |
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