Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
[Auszug] A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggest...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Bryder, David [verfasserIn] Seita, Jun [verfasserIn] Nussenzweig, Andre [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
s.l.: Nature Publishing Group ; 2007 |
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| Umfang: |
5 |
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| Reproduktion: |
Nature Archives 1869 - 2009 |
|---|---|
| Übergeordnetes Werk: |
In: Nature |
| Übergeordnetes Werk: |
volume:447 ; year:2007 ; number:7145 ; month:00 ; pages:725-729 ; extent:5 |
| Links: |
|---|
| DOI / URN: |
10.1038/nature05862 |
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10.1038/nature05862 doi (DE-627)NLEJ234680857 DE-627 ger DE-627 rakwb eng Bryder, David verfasserin aut Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age [s.l.] Nature Publishing Group 2007 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggested ... Nature Archives 1869 - 2009 Seita, Jun verfasserin aut Nussenzweig, Andre verfasserin aut Hoeijmakers, Jan oth Weissman, Irving L. oth Rossi, Derrick J. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 447(2007), 7145, Seite 725-729 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:447 year:2007 number:7145 month:00 pages:725-729 extent:5 http://dx.doi.org/10.1038/nature05862 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 447 2007 7145 0 725-729 5 |
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10.1038/nature05862 doi (DE-627)NLEJ234680857 DE-627 ger DE-627 rakwb eng Bryder, David verfasserin aut Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age [s.l.] Nature Publishing Group 2007 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggested ... Nature Archives 1869 - 2009 Seita, Jun verfasserin aut Nussenzweig, Andre verfasserin aut Hoeijmakers, Jan oth Weissman, Irving L. oth Rossi, Derrick J. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 447(2007), 7145, Seite 725-729 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:447 year:2007 number:7145 month:00 pages:725-729 extent:5 http://dx.doi.org/10.1038/nature05862 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 447 2007 7145 0 725-729 5 |
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10.1038/nature05862 doi (DE-627)NLEJ234680857 DE-627 ger DE-627 rakwb eng Bryder, David verfasserin aut Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age [s.l.] Nature Publishing Group 2007 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggested ... Nature Archives 1869 - 2009 Seita, Jun verfasserin aut Nussenzweig, Andre verfasserin aut Hoeijmakers, Jan oth Weissman, Irving L. oth Rossi, Derrick J. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 447(2007), 7145, Seite 725-729 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:447 year:2007 number:7145 month:00 pages:725-729 extent:5 http://dx.doi.org/10.1038/nature05862 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 447 2007 7145 0 725-729 5 |
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10.1038/nature05862 doi (DE-627)NLEJ234680857 DE-627 ger DE-627 rakwb eng Bryder, David verfasserin aut Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age [s.l.] Nature Publishing Group 2007 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggested ... Nature Archives 1869 - 2009 Seita, Jun verfasserin aut Nussenzweig, Andre verfasserin aut Hoeijmakers, Jan oth Weissman, Irving L. oth Rossi, Derrick J. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 447(2007), 7145, Seite 725-729 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:447 year:2007 number:7145 month:00 pages:725-729 extent:5 http://dx.doi.org/10.1038/nature05862 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 447 2007 7145 0 725-729 5 |
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10.1038/nature05862 doi (DE-627)NLEJ234680857 DE-627 ger DE-627 rakwb eng Bryder, David verfasserin aut Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age [s.l.] Nature Publishing Group 2007 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggested ... Nature Archives 1869 - 2009 Seita, Jun verfasserin aut Nussenzweig, Andre verfasserin aut Hoeijmakers, Jan oth Weissman, Irving L. oth Rossi, Derrick J. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 447(2007), 7145, Seite 725-729 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:447 year:2007 number:7145 month:00 pages:725-729 extent:5 http://dx.doi.org/10.1038/nature05862 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 447 2007 7145 0 725-729 5 |
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