BRAF mutation predicts sensitivity to MEK inhibition
[Auszug] The kinase pathway comprising RAS, RAF, mitogen-activated protein kinase kinase (MEK) and extracellular signal regulated kinase (ERK) is activated in most human tumours, often through gain-of-function mutations of RAS and RAF family members. ...
Gespeichert in:
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E-Artikel |
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Englisch |
| Erschienen: |
s.l.: Nature Publishing Group ; 2006 |
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| Umfang: |
5 |
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| Reproduktion: |
Nature Archives 1869 - 2009 |
|---|---|
| Übergeordnetes Werk: |
In: Nature |
| Übergeordnetes Werk: |
volume:439 ; year:2006 ; number:7074 ; month:01 ; pages:358-362 ; extent:5 |
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| DOI / URN: |
10.1038/nature04304 |
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10.1038/nature04304 doi (DE-627)NLEJ234723149 DE-627 ger DE-627 rakwb eng BRAF mutation predicts sensitivity to MEK inhibition [s.l.] Nature Publishing Group 2006 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] The kinase pathway comprising RAS, RAF, mitogen-activated protein kinase kinase (MEK) and extracellular signal regulated kinase (ERK) is activated in most human tumours, often through gain-of-function mutations of RAS and RAF family members. ... Nature Archives 1869 - 2009 Solit, David B. oth Garraway, Levi A. oth Pratilas, Christine A. oth Sawai, Ayana oth Getz, Gad oth Basso, Andrea oth Ye, Qing oth Lobo, Jose M. oth She, Yuhong oth Osman, Iman oth Golub, Todd R. oth Sebolt-Leopold, Judith oth Sellers, William R. oth Rosen, Neal oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 439(2006), 7074 vom: Jan., Seite 358-362 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:439 year:2006 number:7074 month:01 pages:358-362 extent:5 http://dx.doi.org/10.1038/nature04304 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 439 2006 7074 1 358-362 5 |
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10.1038/nature04304 doi (DE-627)NLEJ234723149 DE-627 ger DE-627 rakwb eng BRAF mutation predicts sensitivity to MEK inhibition [s.l.] Nature Publishing Group 2006 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] The kinase pathway comprising RAS, RAF, mitogen-activated protein kinase kinase (MEK) and extracellular signal regulated kinase (ERK) is activated in most human tumours, often through gain-of-function mutations of RAS and RAF family members. ... Nature Archives 1869 - 2009 Solit, David B. oth Garraway, Levi A. oth Pratilas, Christine A. oth Sawai, Ayana oth Getz, Gad oth Basso, Andrea oth Ye, Qing oth Lobo, Jose M. oth She, Yuhong oth Osman, Iman oth Golub, Todd R. oth Sebolt-Leopold, Judith oth Sellers, William R. oth Rosen, Neal oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 439(2006), 7074 vom: Jan., Seite 358-362 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:439 year:2006 number:7074 month:01 pages:358-362 extent:5 http://dx.doi.org/10.1038/nature04304 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 439 2006 7074 1 358-362 5 |
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10.1038/nature04304 doi (DE-627)NLEJ234723149 DE-627 ger DE-627 rakwb eng BRAF mutation predicts sensitivity to MEK inhibition [s.l.] Nature Publishing Group 2006 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] The kinase pathway comprising RAS, RAF, mitogen-activated protein kinase kinase (MEK) and extracellular signal regulated kinase (ERK) is activated in most human tumours, often through gain-of-function mutations of RAS and RAF family members. ... Nature Archives 1869 - 2009 Solit, David B. oth Garraway, Levi A. oth Pratilas, Christine A. oth Sawai, Ayana oth Getz, Gad oth Basso, Andrea oth Ye, Qing oth Lobo, Jose M. oth She, Yuhong oth Osman, Iman oth Golub, Todd R. oth Sebolt-Leopold, Judith oth Sellers, William R. oth Rosen, Neal oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 439(2006), 7074 vom: Jan., Seite 358-362 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:439 year:2006 number:7074 month:01 pages:358-362 extent:5 http://dx.doi.org/10.1038/nature04304 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 439 2006 7074 1 358-362 5 |
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10.1038/nature04304 doi (DE-627)NLEJ234723149 DE-627 ger DE-627 rakwb eng BRAF mutation predicts sensitivity to MEK inhibition [s.l.] Nature Publishing Group 2006 5 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] The kinase pathway comprising RAS, RAF, mitogen-activated protein kinase kinase (MEK) and extracellular signal regulated kinase (ERK) is activated in most human tumours, often through gain-of-function mutations of RAS and RAF family members. ... Nature Archives 1869 - 2009 Solit, David B. oth Garraway, Levi A. oth Pratilas, Christine A. oth Sawai, Ayana oth Getz, Gad oth Basso, Andrea oth Ye, Qing oth Lobo, Jose M. oth She, Yuhong oth Osman, Iman oth Golub, Todd R. oth Sebolt-Leopold, Judith oth Sellers, William R. oth Rosen, Neal oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 439(2006), 7074 vom: Jan., Seite 358-362 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:439 year:2006 number:7074 month:01 pages:358-362 extent:5 http://dx.doi.org/10.1038/nature04304 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 439 2006 7074 1 358-362 5 |
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