Vascular system defects and neuronal apoptosis in mice lacking Ras GTPase-activating protein

[Auszug] The gene encoding p120-rasGAP, a negative regulator of Ras, has been disrupted in mice. This Gap mutation affects the ability of endothelial cells to organize into a highly vascularized network and results in extensive neuronal cell death. Mutations in the Gap and Nfl genes have a ...

Gespeichert in:
Autor*in:

Henkemeyer, Mark

Rossi, Derrick J.

Holmyard, Douglas P.

Puri, Mira C.

Mbamalu, Geraldine

Harpal, Kendraprasad

Shih, T. Shane

Jacks, Tyler

Pawson, Tony

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

s.l.: Nature Publishing Group ; 1995

Umfang:

7

Reproduktion:

Nature Archives 1869 - 2009

Übergeordnetes Werk:

In: Nature - London [u.a.] : Nature Publising Group, 1869, 377(1995), 6551 vom: Feb., Seite 695-701

Übergeordnetes Werk:

volume:377 ; year:1995 ; number:6551 ; month:02 ; pages:695-701 ; extent:7

Links:

Link aufrufen

DOI / URN:

10.1038/377695a0

Katalog-ID:

NLEJ235044490

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