Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes
[Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic D...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Saiki, Randall K. [verfasserIn] Bugawan, Teodorica L. [verfasserIn] Horn, Glenn T. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
s.l.: Nature Publishing Group ; 1986 |
|---|
| Umfang: |
4 |
|---|
| Reproduktion: |
Nature Archives 1869 - 2009 |
|---|---|
| Übergeordnetes Werk: |
In: Nature |
| Übergeordnetes Werk: |
volume:324 ; year:1986 ; number:6093 ; month:01 ; pages:163-166 ; extent:4 |
| Links: |
|---|
| DOI / URN: |
10.1038/324163a0 |
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| 245 | 1 | 0 | |a Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes |
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| 520 | |a [Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... | ||
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| 700 | 1 | |a Erlich, Henry A. |4 oth | |
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10.1038/324163a0 doi (DE-627)NLEJ235368628 DE-627 ger DE-627 rakwb eng Saiki, Randall K. verfasserin aut Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes [s.l.] Nature Publishing Group 1986 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... Nature Archives 1869 - 2009 Bugawan, Teodorica L. verfasserin aut Horn, Glenn T. verfasserin aut Mullis, Kary B. oth Erlich, Henry A. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 324(1986), 6093 vom: Jan., Seite 163-166 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:324 year:1986 number:6093 month:01 pages:163-166 extent:4 http://dx.doi.org/10.1038/324163a0 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 324 1986 6093 1 163-166 4 |
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10.1038/324163a0 doi (DE-627)NLEJ235368628 DE-627 ger DE-627 rakwb eng Saiki, Randall K. verfasserin aut Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes [s.l.] Nature Publishing Group 1986 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... Nature Archives 1869 - 2009 Bugawan, Teodorica L. verfasserin aut Horn, Glenn T. verfasserin aut Mullis, Kary B. oth Erlich, Henry A. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 324(1986), 6093 vom: Jan., Seite 163-166 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:324 year:1986 number:6093 month:01 pages:163-166 extent:4 http://dx.doi.org/10.1038/324163a0 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 324 1986 6093 1 163-166 4 |
| allfields_unstemmed |
10.1038/324163a0 doi (DE-627)NLEJ235368628 DE-627 ger DE-627 rakwb eng Saiki, Randall K. verfasserin aut Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes [s.l.] Nature Publishing Group 1986 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... Nature Archives 1869 - 2009 Bugawan, Teodorica L. verfasserin aut Horn, Glenn T. verfasserin aut Mullis, Kary B. oth Erlich, Henry A. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 324(1986), 6093 vom: Jan., Seite 163-166 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:324 year:1986 number:6093 month:01 pages:163-166 extent:4 http://dx.doi.org/10.1038/324163a0 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 324 1986 6093 1 163-166 4 |
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10.1038/324163a0 doi (DE-627)NLEJ235368628 DE-627 ger DE-627 rakwb eng Saiki, Randall K. verfasserin aut Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes [s.l.] Nature Publishing Group 1986 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... Nature Archives 1869 - 2009 Bugawan, Teodorica L. verfasserin aut Horn, Glenn T. verfasserin aut Mullis, Kary B. oth Erlich, Henry A. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 324(1986), 6093 vom: Jan., Seite 163-166 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:324 year:1986 number:6093 month:01 pages:163-166 extent:4 http://dx.doi.org/10.1038/324163a0 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 324 1986 6093 1 163-166 4 |
| allfieldsSound |
10.1038/324163a0 doi (DE-627)NLEJ235368628 DE-627 ger DE-627 rakwb eng Saiki, Randall K. verfasserin aut Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes [s.l.] Nature Publishing Group 1986 4 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier [Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... Nature Archives 1869 - 2009 Bugawan, Teodorica L. verfasserin aut Horn, Glenn T. verfasserin aut Mullis, Kary B. oth Erlich, Henry A. oth In Nature <London> London [u.a.] : Nature Publising Group, 1869 324(1986), 6093 vom: Jan., Seite 163-166 (DE-627)NLEJ227682335 (DE-600)1413423-8 1476-4687 nnns volume:324 year:1986 number:6093 month:01 pages:163-166 extent:4 http://dx.doi.org/10.1038/324163a0 application/pdf Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-NTA GBV_NL_ARTICLE AR 324 1986 6093 1 163-166 4 |
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analysis of enzymatically amplified β-globin and hla-dqα dna with allele-specific oligonucleotide probes |
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Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes |
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[Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... |
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[Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... |
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[Auszug] 32P-labelled ASO probes have been used in the analysis of a number of genetic diseases caused by single base mutations, including sickle cell anaemia1, a-1 anti-trypsin deficiency2 and ß-thalassemia3. Although the ASO method is a powerful diagnostic tool, it requires 5 to 10 µg of genomic DNA, ... |
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Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes |
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