Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein
Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have b...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Weibel, Helle [verfasserIn] Hansen, Jens [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1989 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Contact dermatitis - Oxford [u.a.] : Wiley-Blackwell, 1975, 20(1989), 3, Seite 0 |
| Übergeordnetes Werk: |
volume:20 ; year:1989 ; number:3 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1111/j.1600-0536.1989.tb04650.x |
|---|
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NLEJ238552012 |
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| 520 | |a Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. | ||
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10.1111/j.1600-0536.1989.tb04650.x doi (DE-627)NLEJ238552012 DE-627 ger DE-627 rakwb Weibel, Helle verfasserin aut Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| cinnamaldehyde Hansen, Jens verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 20(1989), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:20 year:1989 number:3 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1989.tb04650.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 1989 3 0 |
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10.1111/j.1600-0536.1989.tb04650.x doi (DE-627)NLEJ238552012 DE-627 ger DE-627 rakwb Weibel, Helle verfasserin aut Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| cinnamaldehyde Hansen, Jens verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 20(1989), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:20 year:1989 number:3 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1989.tb04650.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 1989 3 0 |
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10.1111/j.1600-0536.1989.tb04650.x doi (DE-627)NLEJ238552012 DE-627 ger DE-627 rakwb Weibel, Helle verfasserin aut Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| cinnamaldehyde Hansen, Jens verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 20(1989), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:20 year:1989 number:3 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1989.tb04650.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 1989 3 0 |
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10.1111/j.1600-0536.1989.tb04650.x doi (DE-627)NLEJ238552012 DE-627 ger DE-627 rakwb Weibel, Helle verfasserin aut Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| cinnamaldehyde Hansen, Jens verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 20(1989), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:20 year:1989 number:3 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1989.tb04650.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 1989 3 0 |
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10.1111/j.1600-0536.1989.tb04650.x doi (DE-627)NLEJ238552012 DE-627 ger DE-627 rakwb Weibel, Helle verfasserin aut Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| cinnamaldehyde Hansen, Jens verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 20(1989), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:20 year:1989 number:3 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1989.tb04650.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 1989 3 0 |
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In Contact dermatitis 20(1989), 3, Seite 0 volume:20 year:1989 number:3 pages:0 |
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interaction of cinnamaldehyde (a sensitizer in fragrance) with protein |
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Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein |
| abstract |
Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. |
| abstractGer |
Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. |
| abstract_unstemmed |
Formation of a cinnamaldehyde-protein conjugate in the skin by reaction of cinnamaldehyde with nucleophilic groups in proteins is considered to be responsible for the observed immunogenicity. The kinetics of the reaction of bovine serum albumin with cinnamaldehyde in aqueous solution at 30 °C have been investigated, and the rate of formation of conjugate over the pH range 6.4–10.5 showed a first-order dependence on cinnamaldehyde concentration. The cinnamaldehyde binding sites on the protein appeared mostly or exclusively to be the thiol groups of cysteine residues. |
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Interaction of cinnamaldehyde (a sensitizer in fragrance) with protein |
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