Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity
Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate predictio...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
WHITTLE, M. J. [verfasserIn] WILSON, A. I. [verfasserIn] WHITFIELD, C. R. [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1982 |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2005 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: BJOG - Oxford : Wiley-Blackwell, 1902, 89(1982), 9, Seite 0 |
| Übergeordnetes Werk: |
volume:89 ; year:1982 ; number:9 ; pages:0 |
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| DOI / URN: |
10.1111/j.1471-0528.1982.tb05099.x |
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| 520 | |a Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. | ||
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10.1111/j.1471-0528.1982.tb05099.x doi (DE-627)NLEJ238769585 DE-627 ger DE-627 rakwb WHITTLE, M. J. verfasserin aut Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity Oxford, UK Blackwell Publishing Ltd 1982 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| WILSON, A. I. verfasserin aut WHITFIELD, C. R. verfasserin aut PATON, R. D. oth LOGAN, R. W. oth In BJOG Oxford : Wiley-Blackwell, 1902 89(1982), 9, Seite 0 Online-Ressource (DE-627)NLEJ243927851 (DE-600)2036469-6 1471-0528 nnns volume:89 year:1982 number:9 pages:0 http://dx.doi.org/10.1111/j.1471-0528.1982.tb05099.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 89 1982 9 0 |
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10.1111/j.1471-0528.1982.tb05099.x doi (DE-627)NLEJ238769585 DE-627 ger DE-627 rakwb WHITTLE, M. J. verfasserin aut Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity Oxford, UK Blackwell Publishing Ltd 1982 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| WILSON, A. I. verfasserin aut WHITFIELD, C. R. verfasserin aut PATON, R. D. oth LOGAN, R. W. oth In BJOG Oxford : Wiley-Blackwell, 1902 89(1982), 9, Seite 0 Online-Ressource (DE-627)NLEJ243927851 (DE-600)2036469-6 1471-0528 nnns volume:89 year:1982 number:9 pages:0 http://dx.doi.org/10.1111/j.1471-0528.1982.tb05099.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 89 1982 9 0 |
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10.1111/j.1471-0528.1982.tb05099.x doi (DE-627)NLEJ238769585 DE-627 ger DE-627 rakwb WHITTLE, M. J. verfasserin aut Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity Oxford, UK Blackwell Publishing Ltd 1982 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| WILSON, A. I. verfasserin aut WHITFIELD, C. R. verfasserin aut PATON, R. D. oth LOGAN, R. W. oth In BJOG Oxford : Wiley-Blackwell, 1902 89(1982), 9, Seite 0 Online-Ressource (DE-627)NLEJ243927851 (DE-600)2036469-6 1471-0528 nnns volume:89 year:1982 number:9 pages:0 http://dx.doi.org/10.1111/j.1471-0528.1982.tb05099.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 89 1982 9 0 |
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10.1111/j.1471-0528.1982.tb05099.x doi (DE-627)NLEJ238769585 DE-627 ger DE-627 rakwb WHITTLE, M. J. verfasserin aut Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity Oxford, UK Blackwell Publishing Ltd 1982 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| WILSON, A. I. verfasserin aut WHITFIELD, C. R. verfasserin aut PATON, R. D. oth LOGAN, R. W. oth In BJOG Oxford : Wiley-Blackwell, 1902 89(1982), 9, Seite 0 Online-Ressource (DE-627)NLEJ243927851 (DE-600)2036469-6 1471-0528 nnns volume:89 year:1982 number:9 pages:0 http://dx.doi.org/10.1111/j.1471-0528.1982.tb05099.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 89 1982 9 0 |
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10.1111/j.1471-0528.1982.tb05099.x doi (DE-627)NLEJ238769585 DE-627 ger DE-627 rakwb WHITTLE, M. J. verfasserin aut Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity Oxford, UK Blackwell Publishing Ltd 1982 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| WILSON, A. I. verfasserin aut WHITFIELD, C. R. verfasserin aut PATON, R. D. oth LOGAN, R. W. oth In BJOG Oxford : Wiley-Blackwell, 1902 89(1982), 9, Seite 0 Online-Ressource (DE-627)NLEJ243927851 (DE-600)2036469-6 1471-0528 nnns volume:89 year:1982 number:9 pages:0 http://dx.doi.org/10.1111/j.1471-0528.1982.tb05099.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 89 1982 9 0 |
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Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity |
| abstract |
Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. |
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Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. |
| abstract_unstemmed |
Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. It is recommended that laboratories dealing with amniotic fluid from high-risk pregnancies should detect PG as well as measuring the L/S ratio. |
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Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity |
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http://dx.doi.org/10.1111/j.1471-0528.1982.tb05099.x |
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WILSON, A. I. WHITFIELD, C. R. PATON, R. D. LOGAN, R. W. |
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WILSON, A. I. WHITFIELD, C. R. PATON, R. D. LOGAN, R. W. |
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NLEJ243927851 |
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10.1111/j.1471-0528.1982.tb05099.x |
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2024-07-06T05:59:52.649Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ238769585</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707071412.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120417s1982 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1471-0528.1982.tb05099.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ238769585</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">WHITTLE, M. J.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Amniotic fluid phosphatidylglycerol and the lecithin/sphingomyelin ratio in the assessment of fetal lung maturity</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1982</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Summary. Based on the analysis of 561 amniotic fluid samples obtained within 72 h of delivery, including 288 samples collected from the vagina, the detection of phosphatidylglycerol (PG) in the fluid together with the determination of the lecithin/sphingomyelin (L/S) ratio gave an accurate prediction of the risk of the newborn infant developing respiratory distress syndrome (RDS). In the presence of PG, regardless of the L/S ratio, only 0·6% of the babies developed RDS, while absent PG was associated with an 82·8% incidence of RDS. The predictive ability was improved by knowing the L/S ratio since in the presence of both PG and a mature L/S ratio (≥2·0), no baby developed RDS whereas 3·4% of them did when the ratio was immature despite the presence of PG. The test appears to be a useful determinant of the risk of RDS in babies born to diabetic mothers and it seems particularly effective in assessing amniotic fluid collected vaginally. 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