Raynaud's phenomenon and digital necrosis induced by interferon-alpha
We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneou...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
BACHMEYER, C. [verfasserIn] FARGE, D. [verfasserIn] GLUCKMAN, E. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|
| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1996 |
|---|
| Umfang: |
Online-Ressource |
|---|
| Reproduktion: |
2008 ; Blackwell Publishing Journal Backfiles 1879-2005 |
|---|---|
| Übergeordnetes Werk: |
In: British journal of dermatology - Oxford : Wiley-Blackwell, 1892, 135(1996), 3, Seite 0 |
| Übergeordnetes Werk: |
volume:135 ; year:1996 ; number:3 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1046/j.1365-2133.1996.d01-1028.x |
|---|
| Katalog-ID: |
NLEJ238978095 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ238978095 | ||
| 003 | DE-627 | ||
| 005 | 20230505191301.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 120417s1996 xx |||||o 00| ||und c | ||
| 024 | 7 | |a 10.1046/j.1365-2133.1996.d01-1028.x |2 doi | |
| 035 | |a (DE-627)NLEJ238978095 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 100 | 1 | |a BACHMEYER, C. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| 264 | 1 | |a Oxford, UK |b Blackwell Publishing Ltd |c 1996 | |
| 300 | |a Online-Ressource | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. | ||
| 533 | |d 2008 |f Blackwell Publishing Journal Backfiles 1879-2005 |7 |2008|||||||||| | ||
| 700 | 1 | |a FARGE, D. |e verfasserin |4 aut | |
| 700 | 1 | |a GLUCKMAN, E. |e verfasserin |4 aut | |
| 700 | 1 | |a MICLEA, J.M. |4 oth | |
| 700 | 1 | |a ARACTINGI, S. |4 oth | |
| 773 | 0 | 8 | |i In |t British journal of dermatology |d Oxford : Wiley-Blackwell, 1892 |g 135(1996), 3, Seite 0 |h Online-Ressource |w (DE-627)NLEJ24392786X |w (DE-600)2004086-6 |x 1365-2133 |7 nnns |
| 773 | 1 | 8 | |g volume:135 |g year:1996 |g number:3 |g pages:0 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x |q text/html |x Verlag |z Deutschlandweit zugänglich |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a ZDB-1-DJB | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 135 |j 1996 |e 3 |h 0 | ||
| author_variant |
c b cb d f df e g eg |
|---|---|
| matchkey_str |
article:13652133:1996----::anushnmnnndgtlerssnueb |
| hierarchy_sort_str |
1996 |
| publishDate |
1996 |
| allfields |
10.1046/j.1365-2133.1996.d01-1028.x doi (DE-627)NLEJ238978095 DE-627 ger DE-627 rakwb BACHMEYER, C. verfasserin aut Raynaud's phenomenon and digital necrosis induced by interferon-alpha Oxford, UK Blackwell Publishing Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| FARGE, D. verfasserin aut GLUCKMAN, E. verfasserin aut MICLEA, J.M. oth ARACTINGI, S. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 135(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:135 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 135 1996 3 0 |
| spelling |
10.1046/j.1365-2133.1996.d01-1028.x doi (DE-627)NLEJ238978095 DE-627 ger DE-627 rakwb BACHMEYER, C. verfasserin aut Raynaud's phenomenon and digital necrosis induced by interferon-alpha Oxford, UK Blackwell Publishing Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| FARGE, D. verfasserin aut GLUCKMAN, E. verfasserin aut MICLEA, J.M. oth ARACTINGI, S. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 135(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:135 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 135 1996 3 0 |
| allfields_unstemmed |
10.1046/j.1365-2133.1996.d01-1028.x doi (DE-627)NLEJ238978095 DE-627 ger DE-627 rakwb BACHMEYER, C. verfasserin aut Raynaud's phenomenon and digital necrosis induced by interferon-alpha Oxford, UK Blackwell Publishing Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| FARGE, D. verfasserin aut GLUCKMAN, E. verfasserin aut MICLEA, J.M. oth ARACTINGI, S. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 135(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:135 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 135 1996 3 0 |
| allfieldsGer |
10.1046/j.1365-2133.1996.d01-1028.x doi (DE-627)NLEJ238978095 DE-627 ger DE-627 rakwb BACHMEYER, C. verfasserin aut Raynaud's phenomenon and digital necrosis induced by interferon-alpha Oxford, UK Blackwell Publishing Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| FARGE, D. verfasserin aut GLUCKMAN, E. verfasserin aut MICLEA, J.M. oth ARACTINGI, S. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 135(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:135 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 135 1996 3 0 |
| allfieldsSound |
10.1046/j.1365-2133.1996.d01-1028.x doi (DE-627)NLEJ238978095 DE-627 ger DE-627 rakwb BACHMEYER, C. verfasserin aut Raynaud's phenomenon and digital necrosis induced by interferon-alpha Oxford, UK Blackwell Publishing Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| FARGE, D. verfasserin aut GLUCKMAN, E. verfasserin aut MICLEA, J.M. oth ARACTINGI, S. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 135(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:135 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 135 1996 3 0 |
| source |
In British journal of dermatology 135(1996), 3, Seite 0 volume:135 year:1996 number:3 pages:0 |
| sourceStr |
In British journal of dermatology 135(1996), 3, Seite 0 volume:135 year:1996 number:3 pages:0 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| isfreeaccess_bool |
false |
| container_title |
British journal of dermatology |
| authorswithroles_txt_mv |
BACHMEYER, C. @@aut@@ FARGE, D. @@aut@@ GLUCKMAN, E. @@aut@@ MICLEA, J.M. @@oth@@ ARACTINGI, S. @@oth@@ |
| publishDateDaySort_date |
1996-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ24392786X |
| id |
NLEJ238978095 |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ238978095</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505191301.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120417s1996 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1365-2133.1996.d01-1028.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ238978095</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">BACHMEYER, C.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Raynaud's phenomenon and digital necrosis induced by interferon-alpha</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1996</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2008</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2008||||||||||</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">FARGE, D.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">GLUCKMAN, E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">MICLEA, J.M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">ARACTINGI, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">British journal of dermatology</subfield><subfield code="d">Oxford : Wiley-Blackwell, 1892</subfield><subfield code="g">135(1996), 3, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ24392786X</subfield><subfield code="w">(DE-600)2004086-6</subfield><subfield code="x">1365-2133</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:135</subfield><subfield code="g">year:1996</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">135</subfield><subfield code="j">1996</subfield><subfield code="e">3</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| series2 |
Blackwell Publishing Journal Backfiles 1879-2005 |
| author |
BACHMEYER, C. |
| spellingShingle |
BACHMEYER, C. Raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| authorStr |
BACHMEYER, C. |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ24392786X |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut |
| collection |
NL |
| publishPlace |
Oxford, UK |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1365-2133 |
| topic_title |
Raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| publisher |
Blackwell Publishing Ltd |
| publisherStr |
Blackwell Publishing Ltd |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
j m jm s a sa |
| hierarchy_parent_title |
British journal of dermatology |
| hierarchy_parent_id |
NLEJ24392786X |
| hierarchy_top_title |
British journal of dermatology |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ24392786X (DE-600)2004086-6 |
| title |
Raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| ctrlnum |
(DE-627)NLEJ238978095 |
| title_full |
Raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| author_sort |
BACHMEYER, C. |
| journal |
British journal of dermatology |
| journalStr |
British journal of dermatology |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
1996 |
| contenttype_str_mv |
zzz |
| container_start_page |
0 |
| author_browse |
BACHMEYER, C. FARGE, D. GLUCKMAN, E. |
| container_volume |
135 |
| physical |
Online-Ressource |
| format_se |
Elektronische Aufsätze |
| author-letter |
BACHMEYER, C. |
| doi_str_mv |
10.1046/j.1365-2133.1996.d01-1028.x |
| author2-role |
verfasserin |
| title_sort |
raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| title_auth |
Raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| abstract |
We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. |
| abstractGer |
We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. |
| abstract_unstemmed |
We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required. |
| collection_details |
GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE |
| container_issue |
3 |
| title_short |
Raynaud's phenomenon and digital necrosis induced by interferon-alpha |
| url |
http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x |
| remote_bool |
true |
| author2 |
FARGE, D. GLUCKMAN, E. MICLEA, J.M. ARACTINGI, S. |
| author2Str |
FARGE, D. GLUCKMAN, E. MICLEA, J.M. ARACTINGI, S. |
| ppnlink |
NLEJ24392786X |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth |
| doi_str |
10.1046/j.1365-2133.1996.d01-1028.x |
| up_date |
2024-07-06T06:25:30.328Z |
| _version_ |
1803809854932910080 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ238978095</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505191301.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120417s1996 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1365-2133.1996.d01-1028.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ238978095</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">BACHMEYER, C.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Raynaud's phenomenon and digital necrosis induced by interferon-alpha</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1996</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">We report two patients treated with interferon-alpha who developed Raynaud's phenomenon followed by multiple digital necrosis. Arteriography of the legs revealed diffuse distal narrowing. Histological examination of the resected tissue showed ischaemic necrosis within the dermis and subcutaneous tissue without vasculitis. Resolution of the symptoms was observed when interferonalpha was withdrawn. Since other causes of Raynaud's phenomenon and digital necrosis were ruled out, a drug cause is likely. Raynaud's phenomenon should be looked for in patients treated with interferon-alpha. If present, immediate withdrawal of the drug is required.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2008</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2008||||||||||</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">FARGE, D.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">GLUCKMAN, E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">MICLEA, J.M.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">ARACTINGI, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">British journal of dermatology</subfield><subfield code="d">Oxford : Wiley-Blackwell, 1892</subfield><subfield code="g">135(1996), 3, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ24392786X</subfield><subfield code="w">(DE-600)2004086-6</subfield><subfield code="x">1365-2133</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:135</subfield><subfield code="g">year:1996</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1028.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">135</subfield><subfield code="j">1996</subfield><subfield code="e">3</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| score |
7.399625 |