Successful 2-week treatment with terbinafine (Lamisil®) for moccasin tinea pedis and tinea manuum
Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placeb...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
WHITE, J.E. [verfasserIn] PERKINS, P.J. [verfasserIn] EVANS, E.G.V. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|
| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1991 |
|---|
| Umfang: |
Online-Ressource |
|---|
| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
|---|---|
| Übergeordnetes Werk: |
In: British journal of dermatology - Oxford : Wiley-Blackwell, 1892, 125(1991), 3, Seite 0 |
| Übergeordnetes Werk: |
volume:125 ; year:1991 ; number:3 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1111/j.1365-2133.1991.tb14752.x |
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| 520 | |a Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. | ||
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10.1111/j.1365-2133.1991.tb14752.x doi (DE-627)NLEJ239001532 DE-627 ger DE-627 rakwb WHITE, J.E. verfasserin aut Successful 2-week treatment with terbinafine (Lamisil®) for moccasin tinea pedis and tinea manuum Oxford, UK Blackwell Publishing Ltd 1991 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| PERKINS, P.J. verfasserin aut EVANS, E.G.V. verfasserin aut In British journal of dermatology Oxford : Wiley-Blackwell, 1892 125(1991), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:125 year:1991 number:3 pages:0 http://dx.doi.org/10.1111/j.1365-2133.1991.tb14752.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 125 1991 3 0 |
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10.1111/j.1365-2133.1991.tb14752.x doi (DE-627)NLEJ239001532 DE-627 ger DE-627 rakwb WHITE, J.E. verfasserin aut Successful 2-week treatment with terbinafine (Lamisil®) for moccasin tinea pedis and tinea manuum Oxford, UK Blackwell Publishing Ltd 1991 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| PERKINS, P.J. verfasserin aut EVANS, E.G.V. verfasserin aut In British journal of dermatology Oxford : Wiley-Blackwell, 1892 125(1991), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:125 year:1991 number:3 pages:0 http://dx.doi.org/10.1111/j.1365-2133.1991.tb14752.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 125 1991 3 0 |
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10.1111/j.1365-2133.1991.tb14752.x doi (DE-627)NLEJ239001532 DE-627 ger DE-627 rakwb WHITE, J.E. verfasserin aut Successful 2-week treatment with terbinafine (Lamisil®) for moccasin tinea pedis and tinea manuum Oxford, UK Blackwell Publishing Ltd 1991 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| PERKINS, P.J. verfasserin aut EVANS, E.G.V. verfasserin aut In British journal of dermatology Oxford : Wiley-Blackwell, 1892 125(1991), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:125 year:1991 number:3 pages:0 http://dx.doi.org/10.1111/j.1365-2133.1991.tb14752.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 125 1991 3 0 |
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10.1111/j.1365-2133.1991.tb14752.x doi (DE-627)NLEJ239001532 DE-627 ger DE-627 rakwb WHITE, J.E. verfasserin aut Successful 2-week treatment with terbinafine (Lamisil®) for moccasin tinea pedis and tinea manuum Oxford, UK Blackwell Publishing Ltd 1991 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| PERKINS, P.J. verfasserin aut EVANS, E.G.V. verfasserin aut In British journal of dermatology Oxford : Wiley-Blackwell, 1892 125(1991), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:125 year:1991 number:3 pages:0 http://dx.doi.org/10.1111/j.1365-2133.1991.tb14752.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 125 1991 3 0 |
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10.1111/j.1365-2133.1991.tb14752.x doi (DE-627)NLEJ239001532 DE-627 ger DE-627 rakwb WHITE, J.E. verfasserin aut Successful 2-week treatment with terbinafine (Lamisil®) for moccasin tinea pedis and tinea manuum Oxford, UK Blackwell Publishing Ltd 1991 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| PERKINS, P.J. verfasserin aut EVANS, E.G.V. verfasserin aut In British journal of dermatology Oxford : Wiley-Blackwell, 1892 125(1991), 3, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:125 year:1991 number:3 pages:0 http://dx.doi.org/10.1111/j.1365-2133.1991.tb14752.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 125 1991 3 0 |
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| abstract |
Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. |
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Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. |
| abstract_unstemmed |
Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ239001532</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505191315.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120417s1991 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1365-2133.1991.tb14752.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ239001532</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">WHITE, J.E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Successful 2-week treatment with terbinafine (Lamisil®) for moccasin tinea pedis and tinea manuum</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1991</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Summary A new orally active antifungal agent, terbinafine, was used in the treatment of tinea pedis (‘dry type’ or moccasin type) and tinea manuum. Fifty-three adults over the age of 16 years with fungal infections of the feet and/or hands were treated with either oral terbinafine, 250 mg, or placebo, once daily for 2 weeks. The diagnosis of fungal infection was confirmed by examination of skin scrapings by microscopy and culture. Of these, 28 patients were evaluable for efficacy. At 8 weeks, 12 out of 14 (86%) patients who received terbinafine were mycologically negative (microscopy and culture) compared to one out of 14 (7%) patients on placebo (P<0.001, Fishers exact test, one-sided). At the end of the study 71% of patients in the terbinafine group were judged to have received effective therapy compared to 0% in the placebo group (P<0.001), Terbinafine was well tolerated, and more side-effects were seen in the placebo group.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2006</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2006||||||||||</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">PERKINS, P.J.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">EVANS, E.G.V.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">British journal of dermatology</subfield><subfield code="d">Oxford : Wiley-Blackwell, 1892</subfield><subfield code="g">125(1991), 3, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ24392786X</subfield><subfield code="w">(DE-600)2004086-6</subfield><subfield code="x">1365-2133</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:125</subfield><subfield code="g">year:1991</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1365-2133.1991.tb14752.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">125</subfield><subfield code="j">1991</subfield><subfield code="e">3</subfield><subfield code="h">0</subfield></datafield></record></collection>
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