Double-blind evaluation of effectiveness and safety of flunisolide aerosol for treatment of bronchial asthma in children
A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methachol...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Piacentini, G. L. [verfasserIn] Sette, L. [verfasserIn] Peroni, D. G. [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1990 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2007 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Allergy - Oxford : Blackwell Munksgaard, 1978, 45(1990), 8, Seite 0 |
| Übergeordnetes Werk: |
volume:45 ; year:1990 ; number:8 ; pages:0 |
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| DOI / URN: |
10.1111/j.1398-9995.1990.tb00947.x |
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| 520 | |a A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. | ||
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10.1111/j.1398-9995.1990.tb00947.x doi (DE-627)NLEJ239286448 DE-627 ger DE-627 rakwb Piacentini, G. L. verfasserin aut Double-blind evaluation of effectiveness and safety of flunisolide aerosol for treatment of bronchial asthma in children Oxford, UK Blackwell Publishing Ltd 1990 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| bronchial asthma: bronchial hypereactivity Sette, L. verfasserin aut Peroni, D. G. verfasserin aut Bonizzato, C. oth Bonetti, S. oth Boner, A. L. oth In Allergy Oxford : Blackwell Munksgaard, 1978 45(1990), 8, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:45 year:1990 number:8 pages:0 http://dx.doi.org/10.1111/j.1398-9995.1990.tb00947.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 45 1990 8 0 |
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10.1111/j.1398-9995.1990.tb00947.x doi (DE-627)NLEJ239286448 DE-627 ger DE-627 rakwb Piacentini, G. L. verfasserin aut Double-blind evaluation of effectiveness and safety of flunisolide aerosol for treatment of bronchial asthma in children Oxford, UK Blackwell Publishing Ltd 1990 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| bronchial asthma: bronchial hypereactivity Sette, L. verfasserin aut Peroni, D. G. verfasserin aut Bonizzato, C. oth Bonetti, S. oth Boner, A. L. oth In Allergy Oxford : Blackwell Munksgaard, 1978 45(1990), 8, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:45 year:1990 number:8 pages:0 http://dx.doi.org/10.1111/j.1398-9995.1990.tb00947.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 45 1990 8 0 |
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10.1111/j.1398-9995.1990.tb00947.x doi (DE-627)NLEJ239286448 DE-627 ger DE-627 rakwb Piacentini, G. L. verfasserin aut Double-blind evaluation of effectiveness and safety of flunisolide aerosol for treatment of bronchial asthma in children Oxford, UK Blackwell Publishing Ltd 1990 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| bronchial asthma: bronchial hypereactivity Sette, L. verfasserin aut Peroni, D. G. verfasserin aut Bonizzato, C. oth Bonetti, S. oth Boner, A. L. oth In Allergy Oxford : Blackwell Munksgaard, 1978 45(1990), 8, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:45 year:1990 number:8 pages:0 http://dx.doi.org/10.1111/j.1398-9995.1990.tb00947.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 45 1990 8 0 |
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10.1111/j.1398-9995.1990.tb00947.x doi (DE-627)NLEJ239286448 DE-627 ger DE-627 rakwb Piacentini, G. L. verfasserin aut Double-blind evaluation of effectiveness and safety of flunisolide aerosol for treatment of bronchial asthma in children Oxford, UK Blackwell Publishing Ltd 1990 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| bronchial asthma: bronchial hypereactivity Sette, L. verfasserin aut Peroni, D. G. verfasserin aut Bonizzato, C. oth Bonetti, S. oth Boner, A. L. oth In Allergy Oxford : Blackwell Munksgaard, 1978 45(1990), 8, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:45 year:1990 number:8 pages:0 http://dx.doi.org/10.1111/j.1398-9995.1990.tb00947.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 45 1990 8 0 |
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10.1111/j.1398-9995.1990.tb00947.x doi (DE-627)NLEJ239286448 DE-627 ger DE-627 rakwb Piacentini, G. L. verfasserin aut Double-blind evaluation of effectiveness and safety of flunisolide aerosol for treatment of bronchial asthma in children Oxford, UK Blackwell Publishing Ltd 1990 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| bronchial asthma: bronchial hypereactivity Sette, L. verfasserin aut Peroni, D. G. verfasserin aut Bonizzato, C. oth Bonetti, S. oth Boner, A. L. oth In Allergy Oxford : Blackwell Munksgaard, 1978 45(1990), 8, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:45 year:1990 number:8 pages:0 http://dx.doi.org/10.1111/j.1398-9995.1990.tb00947.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 45 1990 8 0 |
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A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. |
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A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. |
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A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ239286448</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505191156.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1990 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1398-9995.1990.tb00947.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ239286448</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Piacentini, G. L.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Double-blind evaluation of effectiveness and safety of flunisolide aerosol for treatment of bronchial asthma in children</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1990</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">A double-blind study was carried out in 20 asthmatic children in order to evaluate the therapeutic efficacy and safety of inhaled corticosteroid flunisolide. 0.5 mg of the drug was administered by a jet nebulizer twice daily for 2 months. Respiratory symptoms. pulmonary function values and methacholine PC2-FEV2 were evaluated, as also morning cortisol levels, plasma cortisol increase alter ACTH test, and 24-h urinary cortisol excretion. The data obtained show the efficacy of the drug in reducing symptoms. No significant difference was observed in pulmonary function values and in bronchial reactivity results between the two groups. No effect of flunisolide was observed on hypothalamic-pituitary-adrenal function. This study confirms the efficacy and safety of flunisolide (0.5 mg b.i.d.) in the treatment of asthmatic children.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2007</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2007||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">bronchial asthma: bronchial hypereactivity</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sette, L.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Peroni, D. G.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bonizzato, C.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bonetti, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Boner, A. L.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Allergy</subfield><subfield code="d">Oxford : Blackwell Munksgaard, 1978</subfield><subfield code="g">45(1990), 8, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926979</subfield><subfield code="w">(DE-600)2003114-2</subfield><subfield code="x">1398-9995</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:45</subfield><subfield code="g">year:1990</subfield><subfield code="g">number:8</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1398-9995.1990.tb00947.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">45</subfield><subfield code="j">1990</subfield><subfield code="e">8</subfield><subfield code="h">0</subfield></datafield></record></collection>
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