Chemotherapy rapidly alternating with accelerated radiotherapy for advanced carcinoma of the uterine cervix
The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cispl...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Chadha, M. [verfasserIn] Jacobs, A.J. [verfasserIn] Stenson, R. [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Erschienen: |
Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA: Blackwell Science Ins. ; 1995 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2002 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: International journal of gynecological cancer - Oxford [u.a.] : Wiley-Blackwell, 1991, 5(1995), 4, Seite 0 |
| Übergeordnetes Werk: |
volume:5 ; year:1995 ; number:4 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1046/j.1525-1438.1995.05040257.x |
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| 520 | |a The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. | ||
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10.1046/j.1525-1438.1995.05040257.x doi (DE-627)NLEJ239409434 DE-627 ger DE-627 rakwb Chadha, M. verfasserin aut Chemotherapy rapidly alternating with accelerated radiotherapy for advanced carcinoma of the uterine cervix Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA Blackwell Science Ins. 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| cervix Jacobs, A.J. verfasserin aut Stenson, R. verfasserin aut In International journal of gynecological cancer Oxford [u.a.] : Wiley-Blackwell, 1991 5(1995), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926197 (DE-600)2009072-9 1525-1438 nnns volume:5 year:1995 number:4 pages:0 http://dx.doi.org/10.1046/j.1525-1438.1995.05040257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1995 4 0 |
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10.1046/j.1525-1438.1995.05040257.x doi (DE-627)NLEJ239409434 DE-627 ger DE-627 rakwb Chadha, M. verfasserin aut Chemotherapy rapidly alternating with accelerated radiotherapy for advanced carcinoma of the uterine cervix Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA Blackwell Science Ins. 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| cervix Jacobs, A.J. verfasserin aut Stenson, R. verfasserin aut In International journal of gynecological cancer Oxford [u.a.] : Wiley-Blackwell, 1991 5(1995), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926197 (DE-600)2009072-9 1525-1438 nnns volume:5 year:1995 number:4 pages:0 http://dx.doi.org/10.1046/j.1525-1438.1995.05040257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1995 4 0 |
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10.1046/j.1525-1438.1995.05040257.x doi (DE-627)NLEJ239409434 DE-627 ger DE-627 rakwb Chadha, M. verfasserin aut Chemotherapy rapidly alternating with accelerated radiotherapy for advanced carcinoma of the uterine cervix Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA Blackwell Science Ins. 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| cervix Jacobs, A.J. verfasserin aut Stenson, R. verfasserin aut In International journal of gynecological cancer Oxford [u.a.] : Wiley-Blackwell, 1991 5(1995), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926197 (DE-600)2009072-9 1525-1438 nnns volume:5 year:1995 number:4 pages:0 http://dx.doi.org/10.1046/j.1525-1438.1995.05040257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1995 4 0 |
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10.1046/j.1525-1438.1995.05040257.x doi (DE-627)NLEJ239409434 DE-627 ger DE-627 rakwb Chadha, M. verfasserin aut Chemotherapy rapidly alternating with accelerated radiotherapy for advanced carcinoma of the uterine cervix Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA Blackwell Science Ins. 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| cervix Jacobs, A.J. verfasserin aut Stenson, R. verfasserin aut In International journal of gynecological cancer Oxford [u.a.] : Wiley-Blackwell, 1991 5(1995), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926197 (DE-600)2009072-9 1525-1438 nnns volume:5 year:1995 number:4 pages:0 http://dx.doi.org/10.1046/j.1525-1438.1995.05040257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1995 4 0 |
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10.1046/j.1525-1438.1995.05040257.x doi (DE-627)NLEJ239409434 DE-627 ger DE-627 rakwb Chadha, M. verfasserin aut Chemotherapy rapidly alternating with accelerated radiotherapy for advanced carcinoma of the uterine cervix Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA Blackwell Science Ins. 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| cervix Jacobs, A.J. verfasserin aut Stenson, R. verfasserin aut In International journal of gynecological cancer Oxford [u.a.] : Wiley-Blackwell, 1991 5(1995), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926197 (DE-600)2009072-9 1525-1438 nnns volume:5 year:1995 number:4 pages:0 http://dx.doi.org/10.1046/j.1525-1438.1995.05040257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1995 4 0 |
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The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. |
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The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. |
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The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ239409434</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506180137.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1995 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1525-1438.1995.05040257.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ239409434</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Chadha, M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Chemotherapy rapidly alternating with accelerated radiotherapy for advanced carcinoma of the uterine cervix</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA</subfield><subfield code="b">Blackwell Science Ins.</subfield><subfield code="c">1995</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The objective of this study was to determine the feasibility of treating patients with advanced cervical carcinoma using a regimen combining chemotherapy with intermittent hyperfractionated teletherapy. Eight patients with advanced cervical carcinoma were treated with bleomycin, ifosfamide and cisplatin, followed by a 5-day course of hyperfractionated external radiation. Three such courses were given at 21-day intervals. Treatment was completed using standard brachytherapy. Seven of the eight patients were evaluable for response; all obtained a complete response. Two patients developed recurrence (one in the pelvis and one distant) and died of disease. One patient died of treatment complications. The remaining four remain alive and free of disease 9–42 months after treatment. The simultaneous use of chemotherapy and intermittent hyperfractionated teletherapy is a promising strategy for the treatment of cervical carcinoma, resulting in a high rate of complete response.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2002</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2002||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">cervix</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Jacobs, A.J.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Stenson, R.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">International journal of gynecological cancer</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1991</subfield><subfield code="g">5(1995), 4, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926197</subfield><subfield code="w">(DE-600)2009072-9</subfield><subfield code="x">1525-1438</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:5</subfield><subfield code="g">year:1995</subfield><subfield code="g">number:4</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1046/j.1525-1438.1995.05040257.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">5</subfield><subfield code="j">1995</subfield><subfield code="e">4</subfield><subfield code="h">0</subfield></datafield></record></collection>
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