Spectrophotometric identification of 8-hydroxy-5-deazaflavin: NADPH oxidoreductase activity in streptomycetes producing tetracyclines
Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also w...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Novotná, Jana [verfasserIn] Neužil, Jiří [verfasserIn] Hoš?álek, Zdeněk [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1989 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: FEMS microbiology letters - Federation of European Microbiological Societies ; GKD-ID: 114439X, Oxford [u.a.] : Wiley-Blackwell, 1977, 59(1989), 1/2, Seite 0 |
| Übergeordnetes Werk: |
volume:59 ; year:1989 ; number:1/2 ; pages:0 |
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| DOI / URN: |
10.1111/j.1574-6968.1989.tb03118.x |
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| 520 | |a Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. | ||
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10.1111/j.1574-6968.1989.tb03118.x doi (DE-627)NLEJ239744845 DE-627 ger DE-627 rakwb Novotná, Jana verfasserin aut Spectrophotometric identification of 8-hydroxy-5-deazaflavin: NADPH oxidoreductase activity in streptomycetes producing tetracyclines Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| 8-Hydroxy-5-deazaflavin Neužil, Jiří verfasserin aut Hoš?álek, Zdeněk verfasserin aut In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS microbiology letters Oxford [u.a.] : Wiley-Blackwell, 1977 59(1989), 1/2, Seite 0 Online-Ressource (DE-627)NLEJ243927053 (DE-600)1501716-3 1574-6968 nnns volume:59 year:1989 number:1/2 pages:0 http://dx.doi.org/10.1111/j.1574-6968.1989.tb03118.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 1989 1/2 0 |
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10.1111/j.1574-6968.1989.tb03118.x doi (DE-627)NLEJ239744845 DE-627 ger DE-627 rakwb Novotná, Jana verfasserin aut Spectrophotometric identification of 8-hydroxy-5-deazaflavin: NADPH oxidoreductase activity in streptomycetes producing tetracyclines Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| 8-Hydroxy-5-deazaflavin Neužil, Jiří verfasserin aut Hoš?álek, Zdeněk verfasserin aut In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS microbiology letters Oxford [u.a.] : Wiley-Blackwell, 1977 59(1989), 1/2, Seite 0 Online-Ressource (DE-627)NLEJ243927053 (DE-600)1501716-3 1574-6968 nnns volume:59 year:1989 number:1/2 pages:0 http://dx.doi.org/10.1111/j.1574-6968.1989.tb03118.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 1989 1/2 0 |
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10.1111/j.1574-6968.1989.tb03118.x doi (DE-627)NLEJ239744845 DE-627 ger DE-627 rakwb Novotná, Jana verfasserin aut Spectrophotometric identification of 8-hydroxy-5-deazaflavin: NADPH oxidoreductase activity in streptomycetes producing tetracyclines Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| 8-Hydroxy-5-deazaflavin Neužil, Jiří verfasserin aut Hoš?álek, Zdeněk verfasserin aut In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS microbiology letters Oxford [u.a.] : Wiley-Blackwell, 1977 59(1989), 1/2, Seite 0 Online-Ressource (DE-627)NLEJ243927053 (DE-600)1501716-3 1574-6968 nnns volume:59 year:1989 number:1/2 pages:0 http://dx.doi.org/10.1111/j.1574-6968.1989.tb03118.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 1989 1/2 0 |
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10.1111/j.1574-6968.1989.tb03118.x doi (DE-627)NLEJ239744845 DE-627 ger DE-627 rakwb Novotná, Jana verfasserin aut Spectrophotometric identification of 8-hydroxy-5-deazaflavin: NADPH oxidoreductase activity in streptomycetes producing tetracyclines Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| 8-Hydroxy-5-deazaflavin Neužil, Jiří verfasserin aut Hoš?álek, Zdeněk verfasserin aut In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS microbiology letters Oxford [u.a.] : Wiley-Blackwell, 1977 59(1989), 1/2, Seite 0 Online-Ressource (DE-627)NLEJ243927053 (DE-600)1501716-3 1574-6968 nnns volume:59 year:1989 number:1/2 pages:0 http://dx.doi.org/10.1111/j.1574-6968.1989.tb03118.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 1989 1/2 0 |
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10.1111/j.1574-6968.1989.tb03118.x doi (DE-627)NLEJ239744845 DE-627 ger DE-627 rakwb Novotná, Jana verfasserin aut Spectrophotometric identification of 8-hydroxy-5-deazaflavin: NADPH oxidoreductase activity in streptomycetes producing tetracyclines Oxford, UK Blackwell Publishing Ltd 1989 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| 8-Hydroxy-5-deazaflavin Neužil, Jiří verfasserin aut Hoš?álek, Zdeněk verfasserin aut In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS microbiology letters Oxford [u.a.] : Wiley-Blackwell, 1977 59(1989), 1/2, Seite 0 Online-Ressource (DE-627)NLEJ243927053 (DE-600)1501716-3 1574-6968 nnns volume:59 year:1989 number:1/2 pages:0 http://dx.doi.org/10.1111/j.1574-6968.1989.tb03118.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 1989 1/2 0 |
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Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. |
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Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. |
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Abstract Cell-free extracts of vegetative mycelia of Streptomyces aureofaciens and Streptomyces rimosus were found to reduce streptomycete-origin 8-hydroxy-5-deazaisoalloxazine derivatives (SF420) using NADPH as a dnor of hydrogen and electrons. 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F0) also was a substrate, although with a lower reaction rate than that for SF420. NADH could not substitute for NADPH. The F420-reductase activity was also observed in homogenates of S. aureofaciens spores. |
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