T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients
Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the...
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Gespeichert in:
| Autor*in: |
Lolli, Francesco [verfasserIn] Sundqvist, Vivi-Anne [verfasserIn] Castagna, Antonella [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1993 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: FEMS immunology and medical microbiology - Federation of European Microbiological Societies ; GKD-ID: 114439X, Oxford [u.a.] : Wiley-Blackwell, 1993, 7(1993), 1, Seite 0 |
| Übergeordnetes Werk: |
volume:7 ; year:1993 ; number:1 ; pages:0 |
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| DOI / URN: |
10.1111/j.1574-695X.1993.tb00381.x |
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| 520 | |a Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. | ||
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| 700 | 1 | |a Sundqvist, Vivi-Anne |e verfasserin |4 aut | |
| 700 | 1 | |a Castagna, Antonella |e verfasserin |4 aut | |
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| 700 | 1 | |a Olsson, Tomas |4 oth | |
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10.1111/j.1574-695X.1993.tb00381.x doi (DE-627)NLEJ23981410X DE-627 ger DE-627 rakwb Lolli, Francesco verfasserin aut T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients Oxford, UK Blackwell Publishing Ltd 1993 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Cytomegalovirus Sundqvist, Vivi-Anne verfasserin aut Castagna, Antonella verfasserin aut Ljungman, Per oth Linde, Annika oth Andersson, Gudrun oth Olsson, Tomas oth Wahren, Britta oth In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS immunology and medical microbiology Oxford [u.a.] : Wiley-Blackwell, 1993 7(1993), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926014 (DE-600)1500464-8 1574-695X nnns volume:7 year:1993 number:1 pages:0 http://dx.doi.org/10.1111/j.1574-695X.1993.tb00381.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 7 1993 1 0 |
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10.1111/j.1574-695X.1993.tb00381.x doi (DE-627)NLEJ23981410X DE-627 ger DE-627 rakwb Lolli, Francesco verfasserin aut T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients Oxford, UK Blackwell Publishing Ltd 1993 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Cytomegalovirus Sundqvist, Vivi-Anne verfasserin aut Castagna, Antonella verfasserin aut Ljungman, Per oth Linde, Annika oth Andersson, Gudrun oth Olsson, Tomas oth Wahren, Britta oth In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS immunology and medical microbiology Oxford [u.a.] : Wiley-Blackwell, 1993 7(1993), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926014 (DE-600)1500464-8 1574-695X nnns volume:7 year:1993 number:1 pages:0 http://dx.doi.org/10.1111/j.1574-695X.1993.tb00381.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 7 1993 1 0 |
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10.1111/j.1574-695X.1993.tb00381.x doi (DE-627)NLEJ23981410X DE-627 ger DE-627 rakwb Lolli, Francesco verfasserin aut T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients Oxford, UK Blackwell Publishing Ltd 1993 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Cytomegalovirus Sundqvist, Vivi-Anne verfasserin aut Castagna, Antonella verfasserin aut Ljungman, Per oth Linde, Annika oth Andersson, Gudrun oth Olsson, Tomas oth Wahren, Britta oth In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS immunology and medical microbiology Oxford [u.a.] : Wiley-Blackwell, 1993 7(1993), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926014 (DE-600)1500464-8 1574-695X nnns volume:7 year:1993 number:1 pages:0 http://dx.doi.org/10.1111/j.1574-695X.1993.tb00381.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 7 1993 1 0 |
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10.1111/j.1574-695X.1993.tb00381.x doi (DE-627)NLEJ23981410X DE-627 ger DE-627 rakwb Lolli, Francesco verfasserin aut T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients Oxford, UK Blackwell Publishing Ltd 1993 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Cytomegalovirus Sundqvist, Vivi-Anne verfasserin aut Castagna, Antonella verfasserin aut Ljungman, Per oth Linde, Annika oth Andersson, Gudrun oth Olsson, Tomas oth Wahren, Britta oth In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS immunology and medical microbiology Oxford [u.a.] : Wiley-Blackwell, 1993 7(1993), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926014 (DE-600)1500464-8 1574-695X nnns volume:7 year:1993 number:1 pages:0 http://dx.doi.org/10.1111/j.1574-695X.1993.tb00381.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 7 1993 1 0 |
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10.1111/j.1574-695X.1993.tb00381.x doi (DE-627)NLEJ23981410X DE-627 ger DE-627 rakwb Lolli, Francesco verfasserin aut T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients Oxford, UK Blackwell Publishing Ltd 1993 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Cytomegalovirus Sundqvist, Vivi-Anne verfasserin aut Castagna, Antonella verfasserin aut Ljungman, Per oth Linde, Annika oth Andersson, Gudrun oth Olsson, Tomas oth Wahren, Britta oth In Federation of European Microbiological Societies ; GKD-ID: 114439X FEMS immunology and medical microbiology Oxford [u.a.] : Wiley-Blackwell, 1993 7(1993), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926014 (DE-600)1500464-8 1574-695X nnns volume:7 year:1993 number:1 pages:0 http://dx.doi.org/10.1111/j.1574-695X.1993.tb00381.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 7 1993 1 0 |
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t and b cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients |
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T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients |
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Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. |
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Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. |
| abstract_unstemmed |
Abstract We measured the production of interferon-gamma (IFN-γ) from single T cells and the T cell proliferative response to different cytomegalovirus (CMV) antigens in healthy blood donors and bone marrow transplant recipients. The antigens consisted of a CMV nuclear antigen (CMV na) containing the pp65-kDa matrix protein and the immediate early antigens but lacking CMV glycoproteins, and an antigen comprising native CMV glycoproteins (CMV gp). We also measured the IgG antibodies to CMV na and CMV gp. The T cells reacted to CMV na in CMV seropositive blood donors both with the production of IFN-γ and with proliferation, while bone marrow transplant recipients had a deficient T cell response. After stimulation with CMV gp, no T cell response could be observed in CMV seropositive subjects. IgG antibodies to CMV na coexisted in plasma with similar levels of antibodies to CMV gp. |
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T and B cell responses to cytomegalovirus antigens in healthy blood donors and bone marrow transplant recipients |
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Sundqvist, Vivi-Anne Castagna, Antonella Ljungman, Per Linde, Annika Andersson, Gudrun Olsson, Tomas Wahren, Britta |
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Sundqvist, Vivi-Anne Castagna, Antonella Ljungman, Per Linde, Annika Andersson, Gudrun Olsson, Tomas Wahren, Britta |
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10.1111/j.1574-695X.1993.tb00381.x |
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2024-07-06T08:26:12.401Z |
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