Sex Differences in Cytosolic Androgen Receptors in Gonadectomized Male and Female Rats
The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue sampl...
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Gespeichert in:
| Autor*in: |
McGinnis, Marilyn Y. [verfasserIn] Katz, Sarah E. [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford: Blackwell Science Ltd ; 1996 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2003 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Journal of neuroendocrinology - Oxford [u.a.] : Wiley-Blackwell, 1989, 8(1996), 3, Seite 0 |
| Übergeordnetes Werk: |
volume:8 ; year:1996 ; number:3 ; pages:0 |
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| DOI / URN: |
10.1046/j.1365-2826.1996.04494.x |
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| 520 | |a The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. | ||
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10.1046/j.1365-2826.1996.04494.x doi (DE-627)NLEJ240214765 DE-627 ger DE-627 rakwb McGinnis, Marilyn Y. verfasserin aut Sex Differences in Cytosolic Androgen Receptors in Gonadectomized Male and Female Rats Oxford Blackwell Science Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Sex differences Katz, Sarah E. verfasserin aut In Journal of neuroendocrinology Oxford [u.a.] : Wiley-Blackwell, 1989 8(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926375 (DE-600)2007386-0 1365-2826 nnns volume:8 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2826.1996.04494.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 8 1996 3 0 |
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10.1046/j.1365-2826.1996.04494.x doi (DE-627)NLEJ240214765 DE-627 ger DE-627 rakwb McGinnis, Marilyn Y. verfasserin aut Sex Differences in Cytosolic Androgen Receptors in Gonadectomized Male and Female Rats Oxford Blackwell Science Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Sex differences Katz, Sarah E. verfasserin aut In Journal of neuroendocrinology Oxford [u.a.] : Wiley-Blackwell, 1989 8(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926375 (DE-600)2007386-0 1365-2826 nnns volume:8 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2826.1996.04494.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 8 1996 3 0 |
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10.1046/j.1365-2826.1996.04494.x doi (DE-627)NLEJ240214765 DE-627 ger DE-627 rakwb McGinnis, Marilyn Y. verfasserin aut Sex Differences in Cytosolic Androgen Receptors in Gonadectomized Male and Female Rats Oxford Blackwell Science Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Sex differences Katz, Sarah E. verfasserin aut In Journal of neuroendocrinology Oxford [u.a.] : Wiley-Blackwell, 1989 8(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926375 (DE-600)2007386-0 1365-2826 nnns volume:8 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2826.1996.04494.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 8 1996 3 0 |
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10.1046/j.1365-2826.1996.04494.x doi (DE-627)NLEJ240214765 DE-627 ger DE-627 rakwb McGinnis, Marilyn Y. verfasserin aut Sex Differences in Cytosolic Androgen Receptors in Gonadectomized Male and Female Rats Oxford Blackwell Science Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Sex differences Katz, Sarah E. verfasserin aut In Journal of neuroendocrinology Oxford [u.a.] : Wiley-Blackwell, 1989 8(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926375 (DE-600)2007386-0 1365-2826 nnns volume:8 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2826.1996.04494.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 8 1996 3 0 |
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10.1046/j.1365-2826.1996.04494.x doi (DE-627)NLEJ240214765 DE-627 ger DE-627 rakwb McGinnis, Marilyn Y. verfasserin aut Sex Differences in Cytosolic Androgen Receptors in Gonadectomized Male and Female Rats Oxford Blackwell Science Ltd 1996 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Sex differences Katz, Sarah E. verfasserin aut In Journal of neuroendocrinology Oxford [u.a.] : Wiley-Blackwell, 1989 8(1996), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926375 (DE-600)2007386-0 1365-2826 nnns volume:8 year:1996 number:3 pages:0 http://dx.doi.org/10.1046/j.1365-2826.1996.04494.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 8 1996 3 0 |
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The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. |
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The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. |
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The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ240214765</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707104515.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1996 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1365-2826.1996.04494.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ240214765</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">McGinnis, Marilyn Y.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Sex Differences in Cytosolic Androgen Receptors in Gonadectomized Male and Female Rats</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford</subfield><subfield code="b">Blackwell Science Ltd</subfield><subfield code="c">1996</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The purpose of this experiment was to determine if there are sex differences in cytosolic androgen receptors (AR) in individual brain nuclei. Bilateral 500 μ diameter samples from 300 μ thick frozen brain sections were micropunched from males and females 2–3 weeks following gonadectomy. Tissue samples were taken from 12 brain nuclei: lateral septum, bed nucleus of the stria terminalis, medial preoptic nucleus, anterior hypothalamic area, arcuate nucleus, corticomedial nucleus of the amygdala, lateral preoptic area, parietal cortex, medial nucleus of the amygdala, dorsomedial nucleus of the hypothalamus, ventromedial nucleus of the hypothalamus, and dorsal hippocampus. Cytosolic ARs were higher in males than in females in each of these 12 areas, but this sex difference was significant only in the first 6. Sex differences in ARs were found in brain regions involved in the neuromodulation of androgen dependent responses. These data suggest that behavioral differences in male reproductive responses may be the result of a sexually dimorphic distribution of androgen receptor containing neurons.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2003</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2003||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sex differences</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Katz, Sarah E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of neuroendocrinology</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1989</subfield><subfield code="g">8(1996), 3, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926375</subfield><subfield code="w">(DE-600)2007386-0</subfield><subfield code="x">1365-2826</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:8</subfield><subfield code="g">year:1996</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1046/j.1365-2826.1996.04494.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">8</subfield><subfield code="j">1996</subfield><subfield code="e">3</subfield><subfield code="h">0</subfield></datafield></record></collection>
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7.4003353 |