A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells
Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Shuman, Sandra [verfasserIn] Hardy, Mattie [verfasserIn] Sobue, Gen [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1988 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Journal of neurochemistry - Oxford : Wiley-Blackwell, 1956, 50(1988), 1, Seite 0 |
| Übergeordnetes Werk: |
volume:50 ; year:1988 ; number:1 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1111/j.1471-4159.1988.tb13248.x |
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| 520 | |a Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. | ||
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10.1111/j.1471-4159.1988.tb13248.x doi (DE-627)NLEJ240283651 DE-627 ger DE-627 rakwb Shuman, Sandra verfasserin aut A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells Oxford, UK Blackwell Publishing Ltd 1988 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Schwann cell Hardy, Mattie verfasserin aut Sobue, Gen verfasserin aut Pleasure, David oth In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 50(1988), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:50 year:1988 number:1 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1988.tb13248.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 50 1988 1 0 |
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10.1111/j.1471-4159.1988.tb13248.x doi (DE-627)NLEJ240283651 DE-627 ger DE-627 rakwb Shuman, Sandra verfasserin aut A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells Oxford, UK Blackwell Publishing Ltd 1988 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Schwann cell Hardy, Mattie verfasserin aut Sobue, Gen verfasserin aut Pleasure, David oth In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 50(1988), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:50 year:1988 number:1 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1988.tb13248.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 50 1988 1 0 |
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10.1111/j.1471-4159.1988.tb13248.x doi (DE-627)NLEJ240283651 DE-627 ger DE-627 rakwb Shuman, Sandra verfasserin aut A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells Oxford, UK Blackwell Publishing Ltd 1988 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Schwann cell Hardy, Mattie verfasserin aut Sobue, Gen verfasserin aut Pleasure, David oth In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 50(1988), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:50 year:1988 number:1 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1988.tb13248.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 50 1988 1 0 |
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10.1111/j.1471-4159.1988.tb13248.x doi (DE-627)NLEJ240283651 DE-627 ger DE-627 rakwb Shuman, Sandra verfasserin aut A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells Oxford, UK Blackwell Publishing Ltd 1988 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Schwann cell Hardy, Mattie verfasserin aut Sobue, Gen verfasserin aut Pleasure, David oth In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 50(1988), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:50 year:1988 number:1 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1988.tb13248.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 50 1988 1 0 |
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10.1111/j.1471-4159.1988.tb13248.x doi (DE-627)NLEJ240283651 DE-627 ger DE-627 rakwb Shuman, Sandra verfasserin aut A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells Oxford, UK Blackwell Publishing Ltd 1988 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Schwann cell Hardy, Mattie verfasserin aut Sobue, Gen verfasserin aut Pleasure, David oth In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 50(1988), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:50 year:1988 number:1 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1988.tb13248.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 50 1988 1 0 |
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A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells |
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Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. |
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Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. |
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Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ240283651</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707105616.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1988 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1471-4159.1988.tb13248.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ240283651</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Shuman, Sandra</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">A Cyclic AMP Analogue Induces Synthesis of a Myelin-Specific Glycoprotein by Cultured Schwann Cells</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1988</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract: Neonatal rat Schwann cells, cultured with agents which increase intracellular cyclic AMP, were prompted to resume synthesis of a 170,000 Mr glycoprotein which is specific to peripheral nervous system myelin and is herein referred to as P170k. We have shown previously that similar treatment induces the synthesis by Schwann cells of the myelin lipid, galactocerebroside. In contrast to P170K and galactocerebroside, syntheses of P0 and myelin basic protein were not induced. Intracellular cyclic AMP is thus likely to be a participant in the complex system regulating myelination.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2006</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2006||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Schwann cell</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hardy, Mattie</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sobue, Gen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pleasure, David</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of neurochemistry</subfield><subfield code="d">Oxford : Wiley-Blackwell, 1956</subfield><subfield code="g">50(1988), 1, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243927584</subfield><subfield code="w">(DE-600)2020528-4</subfield><subfield code="x">1471-4159</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:50</subfield><subfield code="g">year:1988</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1471-4159.1988.tb13248.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">50</subfield><subfield code="j">1988</subfield><subfield code="e">1</subfield><subfield code="h">0</subfield></datafield></record></collection>
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