Distribution and Properties of Thiol S-Methyltransferase in Rat Brain
Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hiemke, Christoph [verfasserIn] Ghraf, Rüdiger [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1983 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Journal of neurochemistry - Oxford : Wiley-Blackwell, 1956, 40(1983), 2, Seite 0 |
| Übergeordnetes Werk: |
volume:40 ; year:1983 ; number:2 ; pages:0 |
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| DOI / URN: |
10.1111/j.1471-4159.1983.tb11325.x |
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| 520 | |a Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. | ||
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10.1111/j.1471-4159.1983.tb11325.x doi (DE-627)NLEJ240311817 DE-627 ger DE-627 rakwb Hiemke, Christoph verfasserin aut Distribution and Properties of Thiol S-Methyltransferase in Rat Brain Oxford, UK Blackwell Publishing Ltd 1983 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Thiol S-methyltransferase Ghraf, Rüdiger verfasserin aut In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 40(1983), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:40 year:1983 number:2 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1983.tb11325.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 40 1983 2 0 |
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10.1111/j.1471-4159.1983.tb11325.x doi (DE-627)NLEJ240311817 DE-627 ger DE-627 rakwb Hiemke, Christoph verfasserin aut Distribution and Properties of Thiol S-Methyltransferase in Rat Brain Oxford, UK Blackwell Publishing Ltd 1983 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Thiol S-methyltransferase Ghraf, Rüdiger verfasserin aut In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 40(1983), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:40 year:1983 number:2 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1983.tb11325.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 40 1983 2 0 |
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10.1111/j.1471-4159.1983.tb11325.x doi (DE-627)NLEJ240311817 DE-627 ger DE-627 rakwb Hiemke, Christoph verfasserin aut Distribution and Properties of Thiol S-Methyltransferase in Rat Brain Oxford, UK Blackwell Publishing Ltd 1983 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Thiol S-methyltransferase Ghraf, Rüdiger verfasserin aut In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 40(1983), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:40 year:1983 number:2 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1983.tb11325.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 40 1983 2 0 |
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10.1111/j.1471-4159.1983.tb11325.x doi (DE-627)NLEJ240311817 DE-627 ger DE-627 rakwb Hiemke, Christoph verfasserin aut Distribution and Properties of Thiol S-Methyltransferase in Rat Brain Oxford, UK Blackwell Publishing Ltd 1983 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Thiol S-methyltransferase Ghraf, Rüdiger verfasserin aut In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 40(1983), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:40 year:1983 number:2 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1983.tb11325.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 40 1983 2 0 |
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10.1111/j.1471-4159.1983.tb11325.x doi (DE-627)NLEJ240311817 DE-627 ger DE-627 rakwb Hiemke, Christoph verfasserin aut Distribution and Properties of Thiol S-Methyltransferase in Rat Brain Oxford, UK Blackwell Publishing Ltd 1983 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Thiol S-methyltransferase Ghraf, Rüdiger verfasserin aut In Journal of neurochemistry Oxford : Wiley-Blackwell, 1956 40(1983), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927584 (DE-600)2020528-4 1471-4159 nnns volume:40 year:1983 number:2 pages:0 http://dx.doi.org/10.1111/j.1471-4159.1983.tb11325.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 40 1983 2 0 |
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Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. |
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Abstract: Microsomal thiol S-methyltransferase (TMT) of rat brain catalysed the methylation of dithiothreitol (Km= 84 μM) and other thiol compounds using S-adenosylmethionine as methyl donor (Km= 3.7 μM). With increasing polarity of thiol substrates there was a decrease in the maximal velocities of reaction and an increase in the apparent Km values. TMT was found to be unevenly distributed amongst various brain regions, with highest activities in the medulla oblongata and the hippocampus. |
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