Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts
Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of f...
Ausführliche Beschreibung
Autor*in: |
Bubien, J. K. [verfasserIn] Meade, T. L. [verfasserIn] |
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E-Artikel |
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Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1986 |
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Online-Ressource |
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Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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Übergeordnetes Werk: |
In: Journal of fish biology - Oxford [u.a.] : Wiley-Blackwell, 1969, 28(1986), 1, Seite 0 |
Übergeordnetes Werk: |
volume:28 ; year:1986 ; number:1 ; pages:0 |
Links: |
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DOI / URN: |
10.1111/j.1095-8649.1986.tb05140.x |
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520 | |a Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. | ||
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10.1111/j.1095-8649.1986.tb05140.x doi (DE-627)NLEJ24061318X DE-627 ger DE-627 rakwb Bubien, J. K. verfasserin aut Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts Oxford, UK Blackwell Publishing Ltd 1986 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Meade, T. L. verfasserin aut In Journal of fish biology Oxford [u.a.] : Wiley-Blackwell, 1969 28(1986), 1, Seite 0 Online-Ressource (DE-627)NLEJ24392741X (DE-600)1471958-7 1095-8649 nnns volume:28 year:1986 number:1 pages:0 http://dx.doi.org/10.1111/j.1095-8649.1986.tb05140.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 28 1986 1 0 |
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10.1111/j.1095-8649.1986.tb05140.x doi (DE-627)NLEJ24061318X DE-627 ger DE-627 rakwb Bubien, J. K. verfasserin aut Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts Oxford, UK Blackwell Publishing Ltd 1986 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Meade, T. L. verfasserin aut In Journal of fish biology Oxford [u.a.] : Wiley-Blackwell, 1969 28(1986), 1, Seite 0 Online-Ressource (DE-627)NLEJ24392741X (DE-600)1471958-7 1095-8649 nnns volume:28 year:1986 number:1 pages:0 http://dx.doi.org/10.1111/j.1095-8649.1986.tb05140.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 28 1986 1 0 |
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10.1111/j.1095-8649.1986.tb05140.x doi (DE-627)NLEJ24061318X DE-627 ger DE-627 rakwb Bubien, J. K. verfasserin aut Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts Oxford, UK Blackwell Publishing Ltd 1986 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Meade, T. L. verfasserin aut In Journal of fish biology Oxford [u.a.] : Wiley-Blackwell, 1969 28(1986), 1, Seite 0 Online-Ressource (DE-627)NLEJ24392741X (DE-600)1471958-7 1095-8649 nnns volume:28 year:1986 number:1 pages:0 http://dx.doi.org/10.1111/j.1095-8649.1986.tb05140.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 28 1986 1 0 |
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10.1111/j.1095-8649.1986.tb05140.x doi (DE-627)NLEJ24061318X DE-627 ger DE-627 rakwb Bubien, J. K. verfasserin aut Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts Oxford, UK Blackwell Publishing Ltd 1986 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Meade, T. L. verfasserin aut In Journal of fish biology Oxford [u.a.] : Wiley-Blackwell, 1969 28(1986), 1, Seite 0 Online-Ressource (DE-627)NLEJ24392741X (DE-600)1471958-7 1095-8649 nnns volume:28 year:1986 number:1 pages:0 http://dx.doi.org/10.1111/j.1095-8649.1986.tb05140.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 28 1986 1 0 |
allfieldsSound |
10.1111/j.1095-8649.1986.tb05140.x doi (DE-627)NLEJ24061318X DE-627 ger DE-627 rakwb Bubien, J. K. verfasserin aut Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts Oxford, UK Blackwell Publishing Ltd 1986 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Meade, T. L. verfasserin aut In Journal of fish biology Oxford [u.a.] : Wiley-Blackwell, 1969 28(1986), 1, Seite 0 Online-Ressource (DE-627)NLEJ24392741X (DE-600)1471958-7 1095-8649 nnns volume:28 year:1986 number:1 pages:0 http://dx.doi.org/10.1111/j.1095-8649.1986.tb05140.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 28 1986 1 0 |
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electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, salvelinus fontinalis, hearts |
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Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts |
abstract |
Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. |
abstractGer |
Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. |
abstract_unstemmed |
Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ24061318X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707114538.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1986 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1095-8649.1986.tb05140.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ24061318X</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Bubien, J. K.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Electrophysiological abnormalities produced by ammonium in isolated perfused brook trout, Salvelinus fontinalis, hearts</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1986</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Electrocardiographic (ECG) abnormalities and arrhythmias have been observed in hyperammonemic patients and in animals injected with ammonium salts. Ammonium is excreted directly into the environment by fish, and it is a potent fish toxin, but the effects of ammonium on the cardiovascular system of fish are unknown. This study investigated the cardiotoxic effects of ammonium on isolated perfused fish hearts. These were compared with ammonium-induced cardiac electrophysiological abnormalities observed in humans and other experimental animals. Isolated perfused fish hearts exhibit ammonium-induced cardiac abnormalities similar to the ammonium-induced abnormalities seen in the hearts of higher vertebrates. Therefore, we conclude that the myocardium of ammonotelic species does not possess a specialized ammonium detoxification mechanism, and that ammonium is cardiotoxic to salmonid fish.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2006</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2006||||||||||</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Meade, T. L.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of fish biology</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1969</subfield><subfield code="g">28(1986), 1, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ24392741X</subfield><subfield code="w">(DE-600)1471958-7</subfield><subfield code="x">1095-8649</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:28</subfield><subfield code="g">year:1986</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1095-8649.1986.tb05140.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">28</subfield><subfield code="j">1986</subfield><subfield code="e">1</subfield><subfield code="h">0</subfield></datafield></record></collection>
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