Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment
Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study a...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hou, Lein-Tuan [verfasserIn] Liu, Cheing-Meei [verfasserIn] Rossomando, Edward F. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|
| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1995 |
|---|
| Schlagwörter: |
|---|
| Umfang: |
Online-Ressource |
|---|
| Reproduktion: |
2005 ; Blackwell Publishing Journal Backfiles 1879-2005 |
|---|---|
| Übergeordnetes Werk: |
In: Journal of clinical periodontology - Oxford [u.a.] : Wiley-Blackwell, 1974, 22(1995), 2, Seite 0 |
| Übergeordnetes Werk: |
volume:22 ; year:1995 ; number:2 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1111/j.1600-051X.1995.tb00128.x |
|---|
| Katalog-ID: |
NLEJ240715802 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ240715802 | ||
| 003 | DE-627 | ||
| 005 | 20230506173911.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 120426s1995 xx |||||o 00| ||und c | ||
| 024 | 7 | |a 10.1111/j.1600-051X.1995.tb00128.x |2 doi | |
| 035 | |a (DE-627)NLEJ240715802 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 100 | 1 | |a Hou, Lein-Tuan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment |
| 264 | 1 | |a Oxford, UK |b Blackwell Publishing Ltd |c 1995 | |
| 300 | |a Online-Ressource | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. | ||
| 533 | |d 2005 |f Blackwell Publishing Journal Backfiles 1879-2005 |7 |2005|||||||||| | ||
| 650 | 4 | |a interleukin-1β | |
| 700 | 1 | |a Liu, Cheing-Meei |e verfasserin |4 aut | |
| 700 | 1 | |a Rossomando, Edward F. |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Journal of clinical periodontology |d Oxford [u.a.] : Wiley-Blackwell, 1974 |g 22(1995), 2, Seite 0 |h Online-Ressource |w (DE-627)NLEJ243927142 |w (DE-600)2026349-1 |x 1600-051X |7 nnns |
| 773 | 1 | 8 | |g volume:22 |g year:1995 |g number:2 |g pages:0 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x |q text/html |x Verlag |z Deutschlandweit zugänglich |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a ZDB-1-DJB | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 22 |j 1995 |e 2 |h 0 | ||
| author_variant |
l t h lth c m l cml e f r ef efr |
|---|---|
| matchkey_str |
article:1600051X:1995----::rvclrnelui1noeaensvrproottsainsntefet |
| hierarchy_sort_str |
1995 |
| publishDate |
1995 |
| allfields |
10.1111/j.1600-051X.1995.tb00128.x doi (DE-627)NLEJ240715802 DE-627 ger DE-627 rakwb Hou, Lein-Tuan verfasserin aut Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment Oxford, UK Blackwell Publishing Ltd 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| interleukin-1β Liu, Cheing-Meei verfasserin aut Rossomando, Edward F. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 22(1995), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:22 year:1995 number:2 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 1995 2 0 |
| spelling |
10.1111/j.1600-051X.1995.tb00128.x doi (DE-627)NLEJ240715802 DE-627 ger DE-627 rakwb Hou, Lein-Tuan verfasserin aut Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment Oxford, UK Blackwell Publishing Ltd 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| interleukin-1β Liu, Cheing-Meei verfasserin aut Rossomando, Edward F. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 22(1995), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:22 year:1995 number:2 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 1995 2 0 |
| allfields_unstemmed |
10.1111/j.1600-051X.1995.tb00128.x doi (DE-627)NLEJ240715802 DE-627 ger DE-627 rakwb Hou, Lein-Tuan verfasserin aut Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment Oxford, UK Blackwell Publishing Ltd 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| interleukin-1β Liu, Cheing-Meei verfasserin aut Rossomando, Edward F. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 22(1995), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:22 year:1995 number:2 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 1995 2 0 |
| allfieldsGer |
10.1111/j.1600-051X.1995.tb00128.x doi (DE-627)NLEJ240715802 DE-627 ger DE-627 rakwb Hou, Lein-Tuan verfasserin aut Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment Oxford, UK Blackwell Publishing Ltd 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| interleukin-1β Liu, Cheing-Meei verfasserin aut Rossomando, Edward F. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 22(1995), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:22 year:1995 number:2 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 1995 2 0 |
| allfieldsSound |
10.1111/j.1600-051X.1995.tb00128.x doi (DE-627)NLEJ240715802 DE-627 ger DE-627 rakwb Hou, Lein-Tuan verfasserin aut Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment Oxford, UK Blackwell Publishing Ltd 1995 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| interleukin-1β Liu, Cheing-Meei verfasserin aut Rossomando, Edward F. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 22(1995), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:22 year:1995 number:2 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 1995 2 0 |
| source |
In Journal of clinical periodontology 22(1995), 2, Seite 0 volume:22 year:1995 number:2 pages:0 |
| sourceStr |
In Journal of clinical periodontology 22(1995), 2, Seite 0 volume:22 year:1995 number:2 pages:0 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
interleukin-1β |
| isfreeaccess_bool |
false |
| container_title |
Journal of clinical periodontology |
| authorswithroles_txt_mv |
Hou, Lein-Tuan @@aut@@ Liu, Cheing-Meei @@aut@@ Rossomando, Edward F. @@aut@@ |
| publishDateDaySort_date |
1995-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ243927142 |
| id |
NLEJ240715802 |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ240715802</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506173911.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1995 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1600-051X.1995.tb00128.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ240715802</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hou, Lein-Tuan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1995</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2005</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2005||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">interleukin-1β</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Liu, Cheing-Meei</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rossomando, Edward F.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of clinical periodontology</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1974</subfield><subfield code="g">22(1995), 2, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243927142</subfield><subfield code="w">(DE-600)2026349-1</subfield><subfield code="x">1600-051X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:22</subfield><subfield code="g">year:1995</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">22</subfield><subfield code="j">1995</subfield><subfield code="e">2</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| series2 |
Blackwell Publishing Journal Backfiles 1879-2005 |
| author |
Hou, Lein-Tuan |
| spellingShingle |
Hou, Lein-Tuan misc interleukin-1β Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment |
| authorStr |
Hou, Lein-Tuan |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ243927142 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut |
| collection |
NL |
| publishPlace |
Oxford, UK |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1600-051X |
| topic_title |
Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment interleukin-1β |
| publisher |
Blackwell Publishing Ltd |
| publisherStr |
Blackwell Publishing Ltd |
| topic |
misc interleukin-1β |
| topic_unstemmed |
misc interleukin-1β |
| topic_browse |
misc interleukin-1β |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| hierarchy_parent_title |
Journal of clinical periodontology |
| hierarchy_parent_id |
NLEJ243927142 |
| hierarchy_top_title |
Journal of clinical periodontology |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ243927142 (DE-600)2026349-1 |
| title |
Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment |
| ctrlnum |
(DE-627)NLEJ240715802 |
| title_full |
Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment |
| author_sort |
Hou, Lein-Tuan |
| journal |
Journal of clinical periodontology |
| journalStr |
Journal of clinical periodontology |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
1995 |
| contenttype_str_mv |
zzz |
| container_start_page |
0 |
| author_browse |
Hou, Lein-Tuan Liu, Cheing-Meei Rossomando, Edward F. |
| container_volume |
22 |
| physical |
Online-Ressource |
| format_se |
Elektronische Aufsätze |
| author-letter |
Hou, Lein-Tuan |
| doi_str_mv |
10.1111/j.1600-051X.1995.tb00128.x |
| author2-role |
verfasserin |
| title_sort |
crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase i periodontal treatment |
| title_auth |
Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment |
| abstract |
Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. |
| abstractGer |
Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. |
| abstract_unstemmed |
Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity. |
| collection_details |
GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE |
| container_issue |
2 |
| title_short |
Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment |
| url |
http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x |
| remote_bool |
true |
| author2 |
Liu, Cheing-Meei Rossomando, Edward F. |
| author2Str |
Liu, Cheing-Meei Rossomando, Edward F. |
| ppnlink |
NLEJ243927142 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1111/j.1600-051X.1995.tb00128.x |
| up_date |
2024-07-06T10:42:43.221Z |
| _version_ |
1803826037492023296 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ240715802</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506173911.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1995 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1600-051X.1995.tb00128.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ240715802</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hou, Lein-Tuan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Crevicular interleukin-1β in moderate and severe periodontitis patients and the effect of phase I periodontal treatment</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1995</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Interleukin-1β (IL-1β), a potent stimulator of bone resorption, has been implicated in the pathogenesis of periodontal destruction. However, the relationship between cytokines and periodontal disease has not been studied sufficiently to allow definitive conclusions. The aims of this study are to investigate crevicular IL-1β and the clinical status of patients with periodontitis and the effect of phase I periodontal therapy on levels of IL-1β. For this study, 130 gingival crevicular fluid (GCF) samples were harvested from non-inflamed (15) and diseased sites (115) in 11 patients with periodontitis. The gingival index (GI) and probing depth (PD) of each site was recorded initially and one month after treatment. The amount of IL-1β in the GCF was measured by enzyme-linked immunosorbent assay (ELISA) using an antibody specific for this cytokine. Before treatment, IL-1β was found in 12 of 15 non-inflamed gingival crevices and in 112 of 115 diseased pockets. The amount of IL-1β varied from 4.03 to 511.12 pg/site. The average amount of IL-1/7 from diseased sites was 3-fold greater than that from non-inflamed sites. Both total amount of IL-1β and the GCF volume, but not IL-1β concentration, were found to be correlated, positively, with GI score and PD. After therapy, 63 sites from 7 patients were re-examined, and the amount of 1L-1β in 49 of 63 sites was found to have declined. These data suggest that the amount of Crevicular IL-1β is closely associated with periodontal status. This relationship may be valuable in monitoring periodontal disease activity.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2005</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2005||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">interleukin-1β</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Liu, Cheing-Meei</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rossomando, Edward F.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of clinical periodontology</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1974</subfield><subfield code="g">22(1995), 2, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243927142</subfield><subfield code="w">(DE-600)2026349-1</subfield><subfield code="x">1600-051X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:22</subfield><subfield code="g">year:1995</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1600-051X.1995.tb00128.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">22</subfield><subfield code="j">1995</subfield><subfield code="e">2</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| score |
7.3971157 |