The Effects of Piracetam Upon Visual Event-Related Potentials in Dyslexic Children
Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-match...
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Oxford, UK: Blackwell Publishing Ltd ; 1987 |
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Online-Ressource |
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2007 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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In: Psychophysiology - Malden, Mass. [u.a.] : Wiley-Blackwell, 1964, 24(1987), 5, Seite 0 |
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volume:24 ; year:1987 ; number:5 ; pages:0 |
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10.1111/j.1469-8986.1987.tb00328.x |
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| 520 | |a Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. | ||
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10.1111/j.1469-8986.1987.tb00328.x doi (DE-627)NLEJ240911962 DE-627 ger DE-627 rakwb The Effects of Piracetam Upon Visual Event-Related Potentials in Dyslexic Children Oxford, UK Blackwell Publishing Ltd 1987 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| Piracetam Conners, C.K. oth Reader, M. oth Reiss, A. oth Caldwell, J. oth Caldwell, L. oth Adesman, A. oth Maver, L. oth Berg, M. oth Clymer, R. oth Erwin, R. oth In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 24(1987), 5, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:24 year:1987 number:5 pages:0 http://dx.doi.org/10.1111/j.1469-8986.1987.tb00328.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 24 1987 5 0 |
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10.1111/j.1469-8986.1987.tb00328.x doi (DE-627)NLEJ240911962 DE-627 ger DE-627 rakwb The Effects of Piracetam Upon Visual Event-Related Potentials in Dyslexic Children Oxford, UK Blackwell Publishing Ltd 1987 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| Piracetam Conners, C.K. oth Reader, M. oth Reiss, A. oth Caldwell, J. oth Caldwell, L. oth Adesman, A. oth Maver, L. oth Berg, M. oth Clymer, R. oth Erwin, R. oth In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 24(1987), 5, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:24 year:1987 number:5 pages:0 http://dx.doi.org/10.1111/j.1469-8986.1987.tb00328.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 24 1987 5 0 |
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10.1111/j.1469-8986.1987.tb00328.x doi (DE-627)NLEJ240911962 DE-627 ger DE-627 rakwb The Effects of Piracetam Upon Visual Event-Related Potentials in Dyslexic Children Oxford, UK Blackwell Publishing Ltd 1987 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| Piracetam Conners, C.K. oth Reader, M. oth Reiss, A. oth Caldwell, J. oth Caldwell, L. oth Adesman, A. oth Maver, L. oth Berg, M. oth Clymer, R. oth Erwin, R. oth In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 24(1987), 5, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:24 year:1987 number:5 pages:0 http://dx.doi.org/10.1111/j.1469-8986.1987.tb00328.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 24 1987 5 0 |
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10.1111/j.1469-8986.1987.tb00328.x doi (DE-627)NLEJ240911962 DE-627 ger DE-627 rakwb The Effects of Piracetam Upon Visual Event-Related Potentials in Dyslexic Children Oxford, UK Blackwell Publishing Ltd 1987 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| Piracetam Conners, C.K. oth Reader, M. oth Reiss, A. oth Caldwell, J. oth Caldwell, L. oth Adesman, A. oth Maver, L. oth Berg, M. oth Clymer, R. oth Erwin, R. oth In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 24(1987), 5, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:24 year:1987 number:5 pages:0 http://dx.doi.org/10.1111/j.1469-8986.1987.tb00328.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 24 1987 5 0 |
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10.1111/j.1469-8986.1987.tb00328.x doi (DE-627)NLEJ240911962 DE-627 ger DE-627 rakwb The Effects of Piracetam Upon Visual Event-Related Potentials in Dyslexic Children Oxford, UK Blackwell Publishing Ltd 1987 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| Piracetam Conners, C.K. oth Reader, M. oth Reiss, A. oth Caldwell, J. oth Caldwell, L. oth Adesman, A. oth Maver, L. oth Berg, M. oth Clymer, R. oth Erwin, R. oth In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 24(1987), 5, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:24 year:1987 number:5 pages:0 http://dx.doi.org/10.1111/j.1469-8986.1987.tb00328.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 24 1987 5 0 |
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the effects of piracetam upon visual event-related potentials in dyslexic children |
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The Effects of Piracetam Upon Visual Event-Related Potentials in Dyslexic Children |
| abstract |
Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. |
| abstractGer |
Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. |
| abstract_unstemmed |
Twenty-nine dyslexic children (mean age 10 yrs) were randomly assigned to piracetam (3.3 gr/d) or matching placebo in a 36-week double-Mind study. Event-related potentials (ERPs) were obtained at the end of treatment from a vigilance paradigm which required a response to letter-matches or form-matches. The drug group showed a significant advantage in letter-bits compared with placebo, and a reduced variance in reaction time. The drug increased the amplitude of three factors from a principal components analysis of ERPs, and was interpreted as increasing a processing negativity when stimuli were letters. Effects upon the prestimulus baseline for letter-hits were interpreted as faster termination of a CNV under drug for letter-pairs. Latency of early N100 components were faster under drug, suggesting improved feature analysis. It is concluded that piracetam enhances feature analysis and increases attentional resources among dyslexics when the stimuli are recognized as having linguistic significance. |
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Conners, C.K. Reader, M. Reiss, A. Caldwell, J. Caldwell, L. Adesman, A. Maver, L. Berg, M. Clymer, R. Erwin, R. |
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Conners, C.K. Reader, M. Reiss, A. Caldwell, J. Caldwell, L. Adesman, A. Maver, L. Berg, M. Clymer, R. Erwin, R. |
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10.1111/j.1469-8986.1987.tb00328.x |
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2024-07-06T11:08:43.825Z |
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