Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells
The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amp...
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| Autor*in: |
PEINADO, PALOMA [verfasserIn] MARTÍNEZ-LIARTE, JOSÉ H. [verfasserIn] SOLANO, FRANCISCO [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1992 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Periodontology 2000 - Oxford [u.a.] : Wiley-Blackwell, 1993, 5(1992), 6, Seite 0 |
| Übergeordnetes Werk: |
volume:5 ; year:1992 ; number:6 ; pages:0 |
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| DOI / URN: |
10.1111/j.1600-0749.1992.tb00570.x |
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| 520 | |a The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. | ||
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10.1111/j.1600-0749.1992.tb00570.x doi (DE-627)NLEJ241158567 DE-627 ger DE-627 rakwb PEINADO, PALOMA verfasserin aut Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells Oxford, UK Blackwell Publishing Ltd 1992 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Melanocytes MARTÍNEZ-LIARTE, JOSÉ H. verfasserin aut SOLANO, FRANCISCO verfasserin aut LOZANO, JOSÉ A. oth In Periodontology 2000 Oxford [u.a.] : Wiley-Blackwell, 1993 5(1992), 6, Seite 0 Online-Ressource (DE-627)NLEJ243925956 (DE-600)2027098-7 1600-0757 nnns volume:5 year:1992 number:6 pages:0 http://dx.doi.org/10.1111/j.1600-0749.1992.tb00570.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1992 6 0 |
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10.1111/j.1600-0749.1992.tb00570.x doi (DE-627)NLEJ241158567 DE-627 ger DE-627 rakwb PEINADO, PALOMA verfasserin aut Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells Oxford, UK Blackwell Publishing Ltd 1992 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Melanocytes MARTÍNEZ-LIARTE, JOSÉ H. verfasserin aut SOLANO, FRANCISCO verfasserin aut LOZANO, JOSÉ A. oth In Periodontology 2000 Oxford [u.a.] : Wiley-Blackwell, 1993 5(1992), 6, Seite 0 Online-Ressource (DE-627)NLEJ243925956 (DE-600)2027098-7 1600-0757 nnns volume:5 year:1992 number:6 pages:0 http://dx.doi.org/10.1111/j.1600-0749.1992.tb00570.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1992 6 0 |
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10.1111/j.1600-0749.1992.tb00570.x doi (DE-627)NLEJ241158567 DE-627 ger DE-627 rakwb PEINADO, PALOMA verfasserin aut Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells Oxford, UK Blackwell Publishing Ltd 1992 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Melanocytes MARTÍNEZ-LIARTE, JOSÉ H. verfasserin aut SOLANO, FRANCISCO verfasserin aut LOZANO, JOSÉ A. oth In Periodontology 2000 Oxford [u.a.] : Wiley-Blackwell, 1993 5(1992), 6, Seite 0 Online-Ressource (DE-627)NLEJ243925956 (DE-600)2027098-7 1600-0757 nnns volume:5 year:1992 number:6 pages:0 http://dx.doi.org/10.1111/j.1600-0749.1992.tb00570.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1992 6 0 |
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10.1111/j.1600-0749.1992.tb00570.x doi (DE-627)NLEJ241158567 DE-627 ger DE-627 rakwb PEINADO, PALOMA verfasserin aut Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells Oxford, UK Blackwell Publishing Ltd 1992 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Melanocytes MARTÍNEZ-LIARTE, JOSÉ H. verfasserin aut SOLANO, FRANCISCO verfasserin aut LOZANO, JOSÉ A. oth In Periodontology 2000 Oxford [u.a.] : Wiley-Blackwell, 1993 5(1992), 6, Seite 0 Online-Ressource (DE-627)NLEJ243925956 (DE-600)2027098-7 1600-0757 nnns volume:5 year:1992 number:6 pages:0 http://dx.doi.org/10.1111/j.1600-0749.1992.tb00570.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1992 6 0 |
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10.1111/j.1600-0749.1992.tb00570.x doi (DE-627)NLEJ241158567 DE-627 ger DE-627 rakwb PEINADO, PALOMA verfasserin aut Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells Oxford, UK Blackwell Publishing Ltd 1992 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Melanocytes MARTÍNEZ-LIARTE, JOSÉ H. verfasserin aut SOLANO, FRANCISCO verfasserin aut LOZANO, JOSÉ A. oth In Periodontology 2000 Oxford [u.a.] : Wiley-Blackwell, 1993 5(1992), 6, Seite 0 Online-Ressource (DE-627)NLEJ243925956 (DE-600)2027098-7 1600-0757 nnns volume:5 year:1992 number:6 pages:0 http://dx.doi.org/10.1111/j.1600-0749.1992.tb00570.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 5 1992 6 0 |
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Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells Melanocytes |
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effect of amphotericin b on dopachrome tautomerase activity and other melanogenic parameters in cultured b16/f10 melanoma cells |
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Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells |
| abstract |
The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. |
| abstractGer |
The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. |
| abstract_unstemmed |
The antifungal reagent Fungizone (amphotericin B and deoxycholate) caused an activation in dopachrome tautomerase and dopa oxidase activities of B16/F10 melanoma cells at the routine concentration (2.5 μg/ml) used for preventing molds and yeast growth in cultures of animal cells. However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. The behavior of dopa oxidase was very similar to that reported by Johnson and Bagnara (Pigment Cell Res. 3, 173–175) for tyrosine hydroxylase. |
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Effect of Amphotericin B on Dopachrome Tautomerase Activity and Other Melanogenic Parameters in Cultured B16/F10 Melanoma Cells |
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http://dx.doi.org/10.1111/j.1600-0749.1992.tb00570.x |
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MARTÍNEZ-LIARTE, JOSÉ H. SOLANO, FRANCISCO LOZANO, JOSÉ A. |
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MARTÍNEZ-LIARTE, JOSÉ H. SOLANO, FRANCISCO LOZANO, JOSÉ A. |
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NLEJ243925956 |
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10.1111/j.1600-0749.1992.tb00570.x |
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2024-07-05T22:02:08.675Z |
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However, higher amphotericin B concentrations caused a significant cell death and the inhibition of enzymatic activities. At the optimal concentration of Fungizone, the enzymatic activities and melanin content were augmented as incubation time increased. The detergent sodium deoxycholate alone exerted no effect on these melanogenic parameters, eliminating the possibility that this detergent was partially responsible for melanogenic modifications produced by Fungizone. After withdrawal of Fungizone from the reaction medium, the recovery of melanogenic parameters to normal values was slower for DCT than for tyrosinase. 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