IONIC PROBES OF MEMBRANE STRUCTURES
In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, p...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Szabo, G. [verfasserIn] Eisenman, G. [verfasserIn] McLaughlin, S. G. A. [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1972 |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Annals of the New York Academy of Sciences - New York Academy of Sciences ; GKD-ID: 363182, Oxford [u.a.] : Wiley-Blackwell, 1877, 195(1972), 1, Seite 0 |
| Übergeordnetes Werk: |
volume:195 ; year:1972 ; number:1 ; pages:0 |
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| DOI / URN: |
10.1111/j.1749-6632.1972.tb54807.x |
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| 520 | |a In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. | ||
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10.1111/j.1749-6632.1972.tb54807.x doi (DE-627)NLEJ24157210X DE-627 ger DE-627 rakwb Szabo, G. verfasserin aut IONIC PROBES OF MEMBRANE STRUCTURES Oxford, UK Blackwell Publishing Ltd 1972 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Eisenman, G. verfasserin aut McLaughlin, S. G. A. verfasserin aut Krasne, S. oth In New York Academy of Sciences ; GKD-ID: 363182 Annals of the New York Academy of Sciences Oxford [u.a.] : Wiley-Blackwell, 1877 195(1972), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927878 (DE-600)2071584-5 1749-6632 nnns volume:195 year:1972 number:1 pages:0 http://dx.doi.org/10.1111/j.1749-6632.1972.tb54807.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 195 1972 1 0 |
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10.1111/j.1749-6632.1972.tb54807.x doi (DE-627)NLEJ24157210X DE-627 ger DE-627 rakwb Szabo, G. verfasserin aut IONIC PROBES OF MEMBRANE STRUCTURES Oxford, UK Blackwell Publishing Ltd 1972 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Eisenman, G. verfasserin aut McLaughlin, S. G. A. verfasserin aut Krasne, S. oth In New York Academy of Sciences ; GKD-ID: 363182 Annals of the New York Academy of Sciences Oxford [u.a.] : Wiley-Blackwell, 1877 195(1972), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927878 (DE-600)2071584-5 1749-6632 nnns volume:195 year:1972 number:1 pages:0 http://dx.doi.org/10.1111/j.1749-6632.1972.tb54807.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 195 1972 1 0 |
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10.1111/j.1749-6632.1972.tb54807.x doi (DE-627)NLEJ24157210X DE-627 ger DE-627 rakwb Szabo, G. verfasserin aut IONIC PROBES OF MEMBRANE STRUCTURES Oxford, UK Blackwell Publishing Ltd 1972 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Eisenman, G. verfasserin aut McLaughlin, S. G. A. verfasserin aut Krasne, S. oth In New York Academy of Sciences ; GKD-ID: 363182 Annals of the New York Academy of Sciences Oxford [u.a.] : Wiley-Blackwell, 1877 195(1972), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927878 (DE-600)2071584-5 1749-6632 nnns volume:195 year:1972 number:1 pages:0 http://dx.doi.org/10.1111/j.1749-6632.1972.tb54807.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 195 1972 1 0 |
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10.1111/j.1749-6632.1972.tb54807.x doi (DE-627)NLEJ24157210X DE-627 ger DE-627 rakwb Szabo, G. verfasserin aut IONIC PROBES OF MEMBRANE STRUCTURES Oxford, UK Blackwell Publishing Ltd 1972 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Eisenman, G. verfasserin aut McLaughlin, S. G. A. verfasserin aut Krasne, S. oth In New York Academy of Sciences ; GKD-ID: 363182 Annals of the New York Academy of Sciences Oxford [u.a.] : Wiley-Blackwell, 1877 195(1972), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927878 (DE-600)2071584-5 1749-6632 nnns volume:195 year:1972 number:1 pages:0 http://dx.doi.org/10.1111/j.1749-6632.1972.tb54807.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 195 1972 1 0 |
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10.1111/j.1749-6632.1972.tb54807.x doi (DE-627)NLEJ24157210X DE-627 ger DE-627 rakwb Szabo, G. verfasserin aut IONIC PROBES OF MEMBRANE STRUCTURES Oxford, UK Blackwell Publishing Ltd 1972 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| Eisenman, G. verfasserin aut McLaughlin, S. G. A. verfasserin aut Krasne, S. oth In New York Academy of Sciences ; GKD-ID: 363182 Annals of the New York Academy of Sciences Oxford [u.a.] : Wiley-Blackwell, 1877 195(1972), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927878 (DE-600)2071584-5 1749-6632 nnns volume:195 year:1972 number:1 pages:0 http://dx.doi.org/10.1111/j.1749-6632.1972.tb54807.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 195 1972 1 0 |
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In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. |
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In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. |
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In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ24157210X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707135335.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120426s1972 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1749-6632.1972.tb54807.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ24157210X</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Szabo, G.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">IONIC PROBES OF MEMBRANE STRUCTURES</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1972</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In this paper we have examined the possibility of identifying those membrane structural variables (polar head groups and the nature of hydrocarbon tails) that modulate membrane ionic permeability. Altering the bilayer lipid composition produces variations in physical parameters (surface potential, partition coefficient, and mobility) governing the conductance mediated by neutral carriers of anions and cations. Specifically, the effects of the charged polar head groups are shown to be understandable in terms of the surface potential they produce through the formation of a diffuse double layer, whereas the effects of the viscosity may be demonstrated by “freezing” the membrane. The effects of membrane composition on membrane conductance are illustrated by a third, less well understood, example of how cholesterol alters bilayer conductances. The results indicate the possibility of using positive and negative permeant species as probes of membrane structures.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2006</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2006||||||||||</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Eisenman, G.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">McLaughlin, S. G. A.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Krasne, S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="a">New York Academy of Sciences ; GKD-ID: 363182</subfield><subfield code="t">Annals of the New York Academy of Sciences</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1877</subfield><subfield code="g">195(1972), 1, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243927878</subfield><subfield code="w">(DE-600)2071584-5</subfield><subfield code="x">1749-6632</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:195</subfield><subfield code="g">year:1972</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1749-6632.1972.tb54807.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">195</subfield><subfield code="j">1972</subfield><subfield code="e">1</subfield><subfield code="h">0</subfield></datafield></record></collection>
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