Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy
Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can...
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| Autor*in: |
Haller, J.C. [verfasserIn] Cairnduff, F. [verfasserIn] Slack, G. [verfasserIn] |
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E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Science Ltd ; 2000 |
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Online-Ressource |
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2001 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: British journal of dermatology - Oxford : Wiley-Blackwell, 1892, 143(2000), 6, Seite 0 |
| Übergeordnetes Werk: |
volume:143 ; year:2000 ; number:6 ; pages:0 |
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| DOI / URN: |
10.1046/j.1365-2133.2000.04000.x |
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| 520 | |a Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. | ||
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10.1046/j.1365-2133.2000.04000.x doi (DE-627)NLEJ242133509 DE-627 ger DE-627 rakwb Haller, J.C. verfasserin aut Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| ALA Cairnduff, F. verfasserin aut Slack, G. verfasserin aut Schofield, J. oth Whitehurst, C. oth Tunstall, R. oth Brown, S.B. oth Roberts, D.J.H. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 143(2000), 6, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:143 year:2000 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2133.2000.04000.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 143 2000 6 0 |
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10.1046/j.1365-2133.2000.04000.x doi (DE-627)NLEJ242133509 DE-627 ger DE-627 rakwb Haller, J.C. verfasserin aut Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| ALA Cairnduff, F. verfasserin aut Slack, G. verfasserin aut Schofield, J. oth Whitehurst, C. oth Tunstall, R. oth Brown, S.B. oth Roberts, D.J.H. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 143(2000), 6, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:143 year:2000 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2133.2000.04000.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 143 2000 6 0 |
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10.1046/j.1365-2133.2000.04000.x doi (DE-627)NLEJ242133509 DE-627 ger DE-627 rakwb Haller, J.C. verfasserin aut Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| ALA Cairnduff, F. verfasserin aut Slack, G. verfasserin aut Schofield, J. oth Whitehurst, C. oth Tunstall, R. oth Brown, S.B. oth Roberts, D.J.H. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 143(2000), 6, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:143 year:2000 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2133.2000.04000.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 143 2000 6 0 |
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10.1046/j.1365-2133.2000.04000.x doi (DE-627)NLEJ242133509 DE-627 ger DE-627 rakwb Haller, J.C. verfasserin aut Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| ALA Cairnduff, F. verfasserin aut Slack, G. verfasserin aut Schofield, J. oth Whitehurst, C. oth Tunstall, R. oth Brown, S.B. oth Roberts, D.J.H. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 143(2000), 6, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:143 year:2000 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2133.2000.04000.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 143 2000 6 0 |
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10.1046/j.1365-2133.2000.04000.x doi (DE-627)NLEJ242133509 DE-627 ger DE-627 rakwb Haller, J.C. verfasserin aut Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| ALA Cairnduff, F. verfasserin aut Slack, G. verfasserin aut Schofield, J. oth Whitehurst, C. oth Tunstall, R. oth Brown, S.B. oth Roberts, D.J.H. oth In British journal of dermatology Oxford : Wiley-Blackwell, 1892 143(2000), 6, Seite 0 Online-Ressource (DE-627)NLEJ24392786X (DE-600)2004086-6 1365-2133 nnns volume:143 year:2000 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2133.2000.04000.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 143 2000 6 0 |
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Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy |
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Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. |
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Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. |
| abstract_unstemmed |
Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. Conclusions We consider routine double treatments with ALA–PDT to be an effective approach to the management of sBCC, particularly those located in anatomically difficult, or cosmetically sensitive, sites. |
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Cairnduff, F. Slack, G. Schofield, J. Whitehurst, C. Tunstall, R. Brown, S.B. Roberts, D.J.H. |
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Cairnduff, F. Slack, G. Schofield, J. Whitehurst, C. Tunstall, R. Brown, S.B. Roberts, D.J.H. |
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10.1046/j.1365-2133.2000.04000.x |
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2024-07-06T00:57:23.610Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242133509</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707150624.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2000 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1365-2133.2000.04000.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242133509</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Haller, J.C.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Science Ltd</subfield><subfield code="c">2000</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Superficial basal cell carcinomas of the skin (sBCC) often respond poorly to single-treatment aminolaevulinic acid-based photodynamic therapy (ALA–PDT), with a number of reports indicating a relapse rate of 50% or more. Objectives To determine whether a second treatment at seven days can improve the response. Methods Twenty-six lesions were treated twice with ALA–PDT, with an interval of 7 days between the two treatment sessions. Results We observed a complete response rate of 100% 1 month after treatment. Only one lesion relapsed (16 months post-PDT), a relapse rate of 4% (median follow up 27 months; range 15–45 months). Cosmetic results were excellent. 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