Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease?
Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux...
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Oxford, UK: Blackwell Science Ltd ; 2004 |
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Online-Ressource |
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2004 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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In: Alimentary pharmacology & therapeutics - Oxford : Blackwell Science, 1987, 20(2004), 10, Seite 0 |
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volume:20 ; year:2004 ; number:10 ; pages:0 |
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DOI / URN: |
10.1111/j.1365-2036.2004.02257.x |
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NLEJ242198228 |
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520 | |a Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. | ||
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10.1111/j.1365-2036.2004.02257.x doi (DE-627)NLEJ242198228 DE-627 ger DE-627 rakwb Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Fallone, C. A. oth Guyatt, G. H. oth Armstrong, D. oth Wiklund, I. oth Degl'Innocenti, A. oth Heels-Ansdell, D. oth Barkun, A. N. oth Chiba, N. oth Zanten, S. J. O. V. oth El-Dika, S. oth Austin, P. oth Tanser, L. oth Schünemann, H. J. oth In Alimentary pharmacology & therapeutics Oxford : Blackwell Science, 1987 20(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926529 (DE-600)2003094-0 1365-2036 nnns volume:20 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1365-2036.2004.02257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 10 0 |
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10.1111/j.1365-2036.2004.02257.x doi (DE-627)NLEJ242198228 DE-627 ger DE-627 rakwb Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Fallone, C. A. oth Guyatt, G. H. oth Armstrong, D. oth Wiklund, I. oth Degl'Innocenti, A. oth Heels-Ansdell, D. oth Barkun, A. N. oth Chiba, N. oth Zanten, S. J. O. V. oth El-Dika, S. oth Austin, P. oth Tanser, L. oth Schünemann, H. J. oth In Alimentary pharmacology & therapeutics Oxford : Blackwell Science, 1987 20(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926529 (DE-600)2003094-0 1365-2036 nnns volume:20 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1365-2036.2004.02257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 10 0 |
allfields_unstemmed |
10.1111/j.1365-2036.2004.02257.x doi (DE-627)NLEJ242198228 DE-627 ger DE-627 rakwb Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Fallone, C. A. oth Guyatt, G. H. oth Armstrong, D. oth Wiklund, I. oth Degl'Innocenti, A. oth Heels-Ansdell, D. oth Barkun, A. N. oth Chiba, N. oth Zanten, S. J. O. V. oth El-Dika, S. oth Austin, P. oth Tanser, L. oth Schünemann, H. J. oth In Alimentary pharmacology & therapeutics Oxford : Blackwell Science, 1987 20(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926529 (DE-600)2003094-0 1365-2036 nnns volume:20 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1365-2036.2004.02257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 10 0 |
allfieldsGer |
10.1111/j.1365-2036.2004.02257.x doi (DE-627)NLEJ242198228 DE-627 ger DE-627 rakwb Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Fallone, C. A. oth Guyatt, G. H. oth Armstrong, D. oth Wiklund, I. oth Degl'Innocenti, A. oth Heels-Ansdell, D. oth Barkun, A. N. oth Chiba, N. oth Zanten, S. J. O. V. oth El-Dika, S. oth Austin, P. oth Tanser, L. oth Schünemann, H. J. oth In Alimentary pharmacology & therapeutics Oxford : Blackwell Science, 1987 20(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926529 (DE-600)2003094-0 1365-2036 nnns volume:20 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1365-2036.2004.02257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 10 0 |
allfieldsSound |
10.1111/j.1365-2036.2004.02257.x doi (DE-627)NLEJ242198228 DE-627 ger DE-627 rakwb Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Fallone, C. A. oth Guyatt, G. H. oth Armstrong, D. oth Wiklund, I. oth Degl'Innocenti, A. oth Heels-Ansdell, D. oth Barkun, A. N. oth Chiba, N. oth Zanten, S. J. O. V. oth El-Dika, S. oth Austin, P. oth Tanser, L. oth Schünemann, H. J. oth In Alimentary pharmacology & therapeutics Oxford : Blackwell Science, 1987 20(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926529 (DE-600)2003094-0 1365-2036 nnns volume:20 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1365-2036.2004.02257.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 10 0 |
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10.1111/j.1365-2036.2004.02257.x |
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do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? |
title_auth |
Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? |
abstract |
Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. |
abstractGer |
Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. |
abstract_unstemmed |
Background : The accuracy of physicians’ assessment of the severity of gastro-oesophageal reflux disease is unclear.Aim : To correlate physician and patient assessment of gastro-oesophageal reflux disease severity and its response to treatment.Methods : Adult uninvestigated gastro-oesophageal reflux disease patients (n = 217) completed symptom and health-related quality of life questionnaires at baseline and after treatment with esomeprazole 40 mg p.o. daily. Pearson coefficients quantified correlations between physician assessments and patient responses.Results : At baseline, the strongest correlations were heartburn severity (0.31), overall symptom severity (0.44) and a domain of the quality of life in reflux and dyspepsia questionnaire (0.31) (P < 0.001). Correlations of change with treatment were greater than baseline correlations: heartburn (0.39), overall symptoms (0.50) and global rate of change – stomach problems (0.72, all P < 0.001). The mean difference between the physicians’ assessment of change and the patients’ global rating of change was 0.20 (95% confidence intervals: 0.10–0.29) with physicians overestimating benefit.Conclusions : Correlations were often significant, although weak to moderate and better with symptom severity than with health-related quality of life instruments as well as with change after therapy than at baseline. Increasing attention to health-related quality of life may help physicians better understand patients’ experience. In clinical trials, treatment success should be assessed by the patient as well as the physician. |
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Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease? |
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Fallone, C. A. Guyatt, G. H. Armstrong, D. Wiklund, I. Degl'Innocenti, A. Heels-Ansdell, D. Barkun, A. N. Chiba, N. Zanten, S. J. O. V. El-Dika, S. Austin, P. Tanser, L. Schünemann, H. J. |
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Fallone, C. A. Guyatt, G. H. Armstrong, D. Wiklund, I. Degl'Innocenti, A. Heels-Ansdell, D. Barkun, A. N. Chiba, N. Zanten, S. J. O. V. El-Dika, S. Austin, P. Tanser, L. Schünemann, H. J. |
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