Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability
Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patien...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Buhner, S. [verfasserIn] Reese, I. [verfasserIn] Kuehl, F. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|
| Erschienen: |
Oxford, UK: Munksgaard International Publishers ; 2004 |
|---|
| Schlagwörter: |
|---|
| Umfang: |
Online-Ressource |
|---|
| Reproduktion: |
2004 ; Blackwell Publishing Journal Backfiles 1879-2005 |
|---|---|
| Übergeordnetes Werk: |
In: Allergy - Oxford : Blackwell Munksgaard, 1978, 59(2004), 10, Seite 0 |
| Übergeordnetes Werk: |
volume:59 ; year:2004 ; number:10 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1111/j.1398-9995.2004.00631.x |
|---|
| Katalog-ID: |
NLEJ242291295 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLEJ242291295 | ||
| 003 | DE-627 | ||
| 005 | 20230506164744.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 120427s2004 xx |||||o 00| ||und c | ||
| 024 | 7 | |a 10.1111/j.1398-9995.2004.00631.x |2 doi | |
| 035 | |a (DE-627)NLEJ242291295 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 100 | 1 | |a Buhner, S. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability |
| 264 | 1 | |a Oxford, UK |b Munksgaard International Publishers |c 2004 | |
| 300 | |a Online-Ressource | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. | ||
| 533 | |d 2004 |f Blackwell Publishing Journal Backfiles 1879-2005 |7 |2004|||||||||| | ||
| 650 | 4 | |a food additives | |
| 700 | 1 | |a Reese, I. |e verfasserin |4 aut | |
| 700 | 1 | |a Kuehl, F. |e verfasserin |4 aut | |
| 700 | 1 | |a Lochs, H. |4 oth | |
| 700 | 1 | |a Zuberbier, T. |4 oth | |
| 773 | 0 | 8 | |i In |t Allergy |d Oxford : Blackwell Munksgaard, 1978 |g 59(2004), 10, Seite 0 |h Online-Ressource |w (DE-627)NLEJ243926979 |w (DE-600)2003114-2 |x 1398-9995 |7 nnns |
| 773 | 1 | 8 | |g volume:59 |g year:2004 |g number:10 |g pages:0 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x |q text/html |x Verlag |z Deutschlandweit zugänglich |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a ZDB-1-DJB | ||
| 912 | |a GBV_NL_ARTICLE | ||
| 951 | |a AR | ||
| 952 | |d 59 |j 2004 |e 10 |h 0 | ||
| author_variant |
s b sb i r ir f k fk |
|---|---|
| matchkey_str |
article:13989995:2004----::suolegcecinicrncriaiaesoitdihleeg |
| hierarchy_sort_str |
2004 |
| publishDate |
2004 |
| allfields |
10.1111/j.1398-9995.2004.00631.x doi (DE-627)NLEJ242291295 DE-627 ger DE-627 rakwb Buhner, S. verfasserin aut Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability Oxford, UK Munksgaard International Publishers 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| food additives Reese, I. verfasserin aut Kuehl, F. verfasserin aut Lochs, H. oth Zuberbier, T. oth In Allergy Oxford : Blackwell Munksgaard, 1978 59(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:59 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 2004 10 0 |
| spelling |
10.1111/j.1398-9995.2004.00631.x doi (DE-627)NLEJ242291295 DE-627 ger DE-627 rakwb Buhner, S. verfasserin aut Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability Oxford, UK Munksgaard International Publishers 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| food additives Reese, I. verfasserin aut Kuehl, F. verfasserin aut Lochs, H. oth Zuberbier, T. oth In Allergy Oxford : Blackwell Munksgaard, 1978 59(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:59 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 2004 10 0 |
| allfields_unstemmed |
10.1111/j.1398-9995.2004.00631.x doi (DE-627)NLEJ242291295 DE-627 ger DE-627 rakwb Buhner, S. verfasserin aut Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability Oxford, UK Munksgaard International Publishers 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| food additives Reese, I. verfasserin aut Kuehl, F. verfasserin aut Lochs, H. oth Zuberbier, T. oth In Allergy Oxford : Blackwell Munksgaard, 1978 59(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:59 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 2004 10 0 |
| allfieldsGer |
10.1111/j.1398-9995.2004.00631.x doi (DE-627)NLEJ242291295 DE-627 ger DE-627 rakwb Buhner, S. verfasserin aut Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability Oxford, UK Munksgaard International Publishers 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| food additives Reese, I. verfasserin aut Kuehl, F. verfasserin aut Lochs, H. oth Zuberbier, T. oth In Allergy Oxford : Blackwell Munksgaard, 1978 59(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:59 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 2004 10 0 |
| allfieldsSound |
10.1111/j.1398-9995.2004.00631.x doi (DE-627)NLEJ242291295 DE-627 ger DE-627 rakwb Buhner, S. verfasserin aut Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability Oxford, UK Munksgaard International Publishers 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| food additives Reese, I. verfasserin aut Kuehl, F. verfasserin aut Lochs, H. oth Zuberbier, T. oth In Allergy Oxford : Blackwell Munksgaard, 1978 59(2004), 10, Seite 0 Online-Ressource (DE-627)NLEJ243926979 (DE-600)2003114-2 1398-9995 nnns volume:59 year:2004 number:10 pages:0 http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 59 2004 10 0 |
| source |
In Allergy 59(2004), 10, Seite 0 volume:59 year:2004 number:10 pages:0 |
| sourceStr |
In Allergy 59(2004), 10, Seite 0 volume:59 year:2004 number:10 pages:0 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
food additives |
| isfreeaccess_bool |
false |
| container_title |
Allergy |
| authorswithroles_txt_mv |
Buhner, S. @@aut@@ Reese, I. @@aut@@ Kuehl, F. @@aut@@ Lochs, H. @@oth@@ Zuberbier, T. @@oth@@ |
| publishDateDaySort_date |
2004-01-01T00:00:00Z |
| hierarchy_top_id |
NLEJ243926979 |
| id |
NLEJ242291295 |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242291295</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506164744.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2004 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1398-9995.2004.00631.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242291295</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Buhner, S.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Munksgaard International Publishers</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2004</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2004||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">food additives</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Reese, I.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kuehl, F.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lochs, H.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zuberbier, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Allergy</subfield><subfield code="d">Oxford : Blackwell Munksgaard, 1978</subfield><subfield code="g">59(2004), 10, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926979</subfield><subfield code="w">(DE-600)2003114-2</subfield><subfield code="x">1398-9995</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:59</subfield><subfield code="g">year:2004</subfield><subfield code="g">number:10</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">59</subfield><subfield code="j">2004</subfield><subfield code="e">10</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| series2 |
Blackwell Publishing Journal Backfiles 1879-2005 |
| author |
Buhner, S. |
| spellingShingle |
Buhner, S. misc food additives Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability |
| authorStr |
Buhner, S. |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)NLEJ243926979 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut |
| collection |
NL |
| publishPlace |
Oxford, UK |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1398-9995 |
| topic_title |
Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability food additives |
| publisher |
Munksgaard International Publishers |
| publisherStr |
Munksgaard International Publishers |
| topic |
misc food additives |
| topic_unstemmed |
misc food additives |
| topic_browse |
misc food additives |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
h l hl t z tz |
| hierarchy_parent_title |
Allergy |
| hierarchy_parent_id |
NLEJ243926979 |
| hierarchy_top_title |
Allergy |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)NLEJ243926979 (DE-600)2003114-2 |
| title |
Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability |
| ctrlnum |
(DE-627)NLEJ242291295 |
| title_full |
Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability |
| author_sort |
Buhner, S. |
| journal |
Allergy |
| journalStr |
Allergy |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2004 |
| contenttype_str_mv |
zzz |
| container_start_page |
0 |
| author_browse |
Buhner, S. Reese, I. Kuehl, F. |
| container_volume |
59 |
| physical |
Online-Ressource |
| format_se |
Elektronische Aufsätze |
| author-letter |
Buhner, S. |
| doi_str_mv |
10.1111/j.1398-9995.2004.00631.x |
| author2-role |
verfasserin |
| title_sort |
pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability |
| title_auth |
Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability |
| abstract |
Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. |
| abstractGer |
Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. |
| abstract_unstemmed |
Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection. |
| collection_details |
GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE |
| container_issue |
10 |
| title_short |
Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability |
| url |
http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x |
| remote_bool |
true |
| author2 |
Reese, I. Kuehl, F. Lochs, H. Zuberbier, T. |
| author2Str |
Reese, I. Kuehl, F. Lochs, H. Zuberbier, T. |
| ppnlink |
NLEJ243926979 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth |
| doi_str |
10.1111/j.1398-9995.2004.00631.x |
| up_date |
2024-07-06T01:29:13.684Z |
| _version_ |
1803791214769602561 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242291295</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506164744.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2004 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1398-9995.2004.00631.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242291295</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Buhner, S.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Munksgaard International Publishers</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: In a subgroup of patients with chronic urticaria (CU) the disease is caused by pseudoallergic reactions to food. The aim of this study was to investigate whether disturbances of the gastrointestinal barrier function play a role in the pathomechanism of the disease.Methods: In 55 patients with CU gastrointestinal permeability was measured with an in vivo triple-sugar-test before and after 24 days of a diet low in pseudoallergens. Sucrose served as marker for gastroduodenal permeability, lactulose/mannitol ratio for intestinal permeability.Results: Basal gastroduodenal and intestinal permeability were significantly higher in patients with urticaria as compared to controls. In 29 of the 55 patients skin symptoms decreased or completely disappeared during the diet (responders). Compared to nonresponders (n = 26), responders had a significantly higher gastroduodenal permeability before treatment (0.36 ± 0.04 vs 0.15 ± 0.01% sucrose; P < 0.001), which decreased after the diet (0.17 ± 0.02; P < 0.001). The number of patients with Helicobacter pylori infections did not differ between the two groups.Conclusions: The results indicate that in a subgroup of patients with CU and pseudoallergy an impaired gastroduodenal barrier function may be of pathophysiological importance. The underlying mechanisms seem to be independent of H. pylori infection.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2004</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2004||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">food additives</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Reese, I.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kuehl, F.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lochs, H.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zuberbier, T.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Allergy</subfield><subfield code="d">Oxford : Blackwell Munksgaard, 1978</subfield><subfield code="g">59(2004), 10, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926979</subfield><subfield code="w">(DE-600)2003114-2</subfield><subfield code="x">1398-9995</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:59</subfield><subfield code="g">year:2004</subfield><subfield code="g">number:10</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1398-9995.2004.00631.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">59</subfield><subfield code="j">2004</subfield><subfield code="e">10</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| score |
7.4012384 |