Neurosteroidogenesis in Oligodendrocytes and Purkinje Neurones of Cerebellar Cortex of Dogs
The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 1...
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Yarim, M. [verfasserIn] Kabakci, N. [verfasserIn] |
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E-Artikel |
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Berlin, Germany: Blackwell Verlag GmbH ; 2004 |
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2004 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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In: Anatomia, histologia, embryologia - Oxford : Blackwell Science, 1972, 33(2004), 3, Seite 0 |
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volume:33 ; year:2004 ; number:3 ; pages:0 |
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10.1111/j.1439-0264.2004.00525.x |
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| 520 | |a The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. | ||
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10.1111/j.1439-0264.2004.00525.x doi (DE-627)NLEJ242326706 DE-627 ger DE-627 rakwb Yarim, M. verfasserin aut Neurosteroidogenesis in Oligodendrocytes and Purkinje Neurones of Cerebellar Cortex of Dogs Berlin, Germany Blackwell Verlag GmbH 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Kabakci, N. verfasserin aut In Anatomia, histologia, embryologia Oxford : Blackwell Science, 1972 33(2004), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927258 (DE-600)2019889-9 1439-0264 nnns volume:33 year:2004 number:3 pages:0 http://dx.doi.org/10.1111/j.1439-0264.2004.00525.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 33 2004 3 0 |
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10.1111/j.1439-0264.2004.00525.x doi (DE-627)NLEJ242326706 DE-627 ger DE-627 rakwb Yarim, M. verfasserin aut Neurosteroidogenesis in Oligodendrocytes and Purkinje Neurones of Cerebellar Cortex of Dogs Berlin, Germany Blackwell Verlag GmbH 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Kabakci, N. verfasserin aut In Anatomia, histologia, embryologia Oxford : Blackwell Science, 1972 33(2004), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927258 (DE-600)2019889-9 1439-0264 nnns volume:33 year:2004 number:3 pages:0 http://dx.doi.org/10.1111/j.1439-0264.2004.00525.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 33 2004 3 0 |
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10.1111/j.1439-0264.2004.00525.x doi (DE-627)NLEJ242326706 DE-627 ger DE-627 rakwb Yarim, M. verfasserin aut Neurosteroidogenesis in Oligodendrocytes and Purkinje Neurones of Cerebellar Cortex of Dogs Berlin, Germany Blackwell Verlag GmbH 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Kabakci, N. verfasserin aut In Anatomia, histologia, embryologia Oxford : Blackwell Science, 1972 33(2004), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927258 (DE-600)2019889-9 1439-0264 nnns volume:33 year:2004 number:3 pages:0 http://dx.doi.org/10.1111/j.1439-0264.2004.00525.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 33 2004 3 0 |
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10.1111/j.1439-0264.2004.00525.x doi (DE-627)NLEJ242326706 DE-627 ger DE-627 rakwb Yarim, M. verfasserin aut Neurosteroidogenesis in Oligodendrocytes and Purkinje Neurones of Cerebellar Cortex of Dogs Berlin, Germany Blackwell Verlag GmbH 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Kabakci, N. verfasserin aut In Anatomia, histologia, embryologia Oxford : Blackwell Science, 1972 33(2004), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927258 (DE-600)2019889-9 1439-0264 nnns volume:33 year:2004 number:3 pages:0 http://dx.doi.org/10.1111/j.1439-0264.2004.00525.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 33 2004 3 0 |
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10.1111/j.1439-0264.2004.00525.x doi (DE-627)NLEJ242326706 DE-627 ger DE-627 rakwb Yarim, M. verfasserin aut Neurosteroidogenesis in Oligodendrocytes and Purkinje Neurones of Cerebellar Cortex of Dogs Berlin, Germany Blackwell Verlag GmbH 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| Kabakci, N. verfasserin aut In Anatomia, histologia, embryologia Oxford : Blackwell Science, 1972 33(2004), 3, Seite 0 Online-Ressource (DE-627)NLEJ243927258 (DE-600)2019889-9 1439-0264 nnns volume:33 year:2004 number:3 pages:0 http://dx.doi.org/10.1111/j.1439-0264.2004.00525.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 33 2004 3 0 |
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The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. |
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The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. |
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The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. This result suggests that endogenous progesterone synthesized de novo in the Purkinje neurone can promote myeline protein synthesis in oligodentrocytes. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242326706</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707153425.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2004 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1439-0264.2004.00525.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242326706</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Yarim, M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Neurosteroidogenesis in Oligodendrocytes and Purkinje Neurones of Cerebellar Cortex of Dogs</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Berlin, Germany</subfield><subfield code="b">Blackwell Verlag GmbH</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The cerebellum is a steroidogenic organ that expresses steroidogenic enzymes and produces neurosteroids. Purkinje neurones appear to be the most active steroidogenic cells in the cerebellar cortex. These neurones express 3β-hydroxysteroid dehydrogenase (3β-HSD), P450 side-chain cleavage (P450scc), 17α-hydroxylase/c17, 20lyase (P450c17), P450 aromatase (P450arom) and produce pregnenolone, progesterone, dehydroepiandrosterone, androstenedion, oestradion and oestrone. Oligodendrocytes are predominantly the producer of myeline protein. The oligodendrocytes were identified by immunohistochemistry using a monoclonal antibody against myeline 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), a myeline specific enzyme. In this study we have examined the distribution of 3β-HSD and CNPase by immunohistochemistry using monoclonal antibody in canine cerebellar cortex. The localization of oligodendrocytes within the cerebellar cortex was determined to be close to Purkinje neurones. 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