Buprenorphine in pregnant opioid-dependent women: first results of a prospective study
Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pre...
Ausführliche Beschreibung
Autor*in: |
Lacroix, I. [verfasserIn] Berrebi, A. [verfasserIn] Chaumerliac, C. [verfasserIn] |
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E-Artikel |
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Erschienen: |
Oxford, UK: Blackwell Science Ltd ; 2004 |
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Online-Ressource |
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2003 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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In: Addiction - Oxford [u.a.] : Wiley-Blackwell, 1993, 99(2004), 2, Seite 0 |
Übergeordnetes Werk: |
volume:99 ; year:2004 ; number:2 ; pages:0 |
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DOI / URN: |
10.1046/j.1360-0443.2003.00600.x |
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NLEJ242338917 |
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520 | |a Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. | ||
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10.1046/j.1360-0443.2003.00600.x doi (DE-627)NLEJ242338917 DE-627 ger DE-627 rakwb Lacroix, I. verfasserin aut Buprenorphine in pregnant opioid-dependent women: first results of a prospective study Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Buprenorphine Berrebi, A. verfasserin aut Chaumerliac, C. verfasserin aut Lapeyre-Mestre, M. oth Montastruc, J. L. oth Damase-Michel, C. oth In Addiction Oxford [u.a.] : Wiley-Blackwell, 1993 99(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926006 (DE-600)2002997-4 1360-0443 nnns volume:99 year:2004 number:2 pages:0 http://dx.doi.org/10.1046/j.1360-0443.2003.00600.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 99 2004 2 0 |
spelling |
10.1046/j.1360-0443.2003.00600.x doi (DE-627)NLEJ242338917 DE-627 ger DE-627 rakwb Lacroix, I. verfasserin aut Buprenorphine in pregnant opioid-dependent women: first results of a prospective study Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Buprenorphine Berrebi, A. verfasserin aut Chaumerliac, C. verfasserin aut Lapeyre-Mestre, M. oth Montastruc, J. L. oth Damase-Michel, C. oth In Addiction Oxford [u.a.] : Wiley-Blackwell, 1993 99(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926006 (DE-600)2002997-4 1360-0443 nnns volume:99 year:2004 number:2 pages:0 http://dx.doi.org/10.1046/j.1360-0443.2003.00600.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 99 2004 2 0 |
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10.1046/j.1360-0443.2003.00600.x doi (DE-627)NLEJ242338917 DE-627 ger DE-627 rakwb Lacroix, I. verfasserin aut Buprenorphine in pregnant opioid-dependent women: first results of a prospective study Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Buprenorphine Berrebi, A. verfasserin aut Chaumerliac, C. verfasserin aut Lapeyre-Mestre, M. oth Montastruc, J. L. oth Damase-Michel, C. oth In Addiction Oxford [u.a.] : Wiley-Blackwell, 1993 99(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926006 (DE-600)2002997-4 1360-0443 nnns volume:99 year:2004 number:2 pages:0 http://dx.doi.org/10.1046/j.1360-0443.2003.00600.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 99 2004 2 0 |
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10.1046/j.1360-0443.2003.00600.x doi (DE-627)NLEJ242338917 DE-627 ger DE-627 rakwb Lacroix, I. verfasserin aut Buprenorphine in pregnant opioid-dependent women: first results of a prospective study Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Buprenorphine Berrebi, A. verfasserin aut Chaumerliac, C. verfasserin aut Lapeyre-Mestre, M. oth Montastruc, J. L. oth Damase-Michel, C. oth In Addiction Oxford [u.a.] : Wiley-Blackwell, 1993 99(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926006 (DE-600)2002997-4 1360-0443 nnns volume:99 year:2004 number:2 pages:0 http://dx.doi.org/10.1046/j.1360-0443.2003.00600.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 99 2004 2 0 |
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10.1046/j.1360-0443.2003.00600.x doi (DE-627)NLEJ242338917 DE-627 ger DE-627 rakwb Lacroix, I. verfasserin aut Buprenorphine in pregnant opioid-dependent women: first results of a prospective study Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| Buprenorphine Berrebi, A. verfasserin aut Chaumerliac, C. verfasserin aut Lapeyre-Mestre, M. oth Montastruc, J. L. oth Damase-Michel, C. oth In Addiction Oxford [u.a.] : Wiley-Blackwell, 1993 99(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926006 (DE-600)2002997-4 1360-0443 nnns volume:99 year:2004 number:2 pages:0 http://dx.doi.org/10.1046/j.1360-0443.2003.00600.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 99 2004 2 0 |
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Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. |
abstractGer |
Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. |
abstract_unstemmed |
Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. However, further data from the comparative prospective study are required to determine whether buprenorphine can be considered as a good alternative to methadone treatment in pregnant women. |
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Buprenorphine in pregnant opioid-dependent women: first results of a prospective study |
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http://dx.doi.org/10.1046/j.1360-0443.2003.00600.x |
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Berrebi, A. Chaumerliac, C. Lapeyre-Mestre, M. Montastruc, J. L. Damase-Michel, C. |
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Berrebi, A. Chaumerliac, C. Lapeyre-Mestre, M. Montastruc, J. L. Damase-Michel, C. |
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NLEJ243926006 |
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doi_str |
10.1046/j.1360-0443.2003.00600.x |
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2024-07-06T01:38:53.396Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242338917</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505195427.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2004 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1360-0443.2003.00600.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242338917</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Lacroix, I.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Buprenorphine in pregnant opioid-dependent women: first results of a prospective study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Science Ltd</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Aim To report results on the prospective follow-up of 34 pregnant women exposed to buprenorphine maintenance for opiate dependence.Design and setting Prospective multicentre study: all pregnant women receiving buprenorphine as maintenance therapy were included as early as possible during their pregnancy.Participants The pregnant women were recruited from opiate maintenance therapy centres, general practitioner-networks involved in addiction, maternity hospitals and centres for drug information during pregnancy.Measurements Women: drugs and medications consumed, medical and obstetrical events; offspring: withdrawal syndrome, malformation, neonatal disease.Findings The buprenorphine-exposed pregnancies resulted in 31 live births, one stillbirth, one spontaneous abortion and one voluntary termination. A neonatal withdrawal syndrome was observed in 13 cases (41.9%) and eight of these babies required opiate treatment. Two neonates had a malformation: a premature ductus arteriosus stricture and a tragus appendix.Conclusion Taken together with other prospective studies, no alarming results were observed concerning pregnancy outcomes. 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