Environmental enrichment enhances auditory takeover of the occipital cortex in anophthalmic mice
Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to...
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| Autor*in: |
Piché, Mathieu [verfasserIn] Robert, Stéphane [verfasserIn] Miceli, Dom [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Science Ltd ; 2004 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2004 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: European journal of neuroscience - Oxford [u.a.] : Blackwell, 1989, 20(2004), 12, Seite 0 |
| Übergeordnetes Werk: |
volume:20 ; year:2004 ; number:12 ; pages:0 |
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| DOI / URN: |
10.1111/j.1460-9568.2004.03823.x |
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| 520 | |a Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. | ||
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10.1111/j.1460-9568.2004.03823.x doi (DE-627)NLEJ242417094 DE-627 ger DE-627 rakwb Piché, Mathieu verfasserin aut Environmental enrichment enhances auditory takeover of the occipital cortex in anophthalmic mice Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| cross-modal compensation Robert, Stéphane verfasserin aut Miceli, Dom verfasserin aut Bronchti, Gilles oth In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 20(2004), 12, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:20 year:2004 number:12 pages:0 http://dx.doi.org/10.1111/j.1460-9568.2004.03823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 12 0 |
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10.1111/j.1460-9568.2004.03823.x doi (DE-627)NLEJ242417094 DE-627 ger DE-627 rakwb Piché, Mathieu verfasserin aut Environmental enrichment enhances auditory takeover of the occipital cortex in anophthalmic mice Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| cross-modal compensation Robert, Stéphane verfasserin aut Miceli, Dom verfasserin aut Bronchti, Gilles oth In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 20(2004), 12, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:20 year:2004 number:12 pages:0 http://dx.doi.org/10.1111/j.1460-9568.2004.03823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 12 0 |
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10.1111/j.1460-9568.2004.03823.x doi (DE-627)NLEJ242417094 DE-627 ger DE-627 rakwb Piché, Mathieu verfasserin aut Environmental enrichment enhances auditory takeover of the occipital cortex in anophthalmic mice Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| cross-modal compensation Robert, Stéphane verfasserin aut Miceli, Dom verfasserin aut Bronchti, Gilles oth In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 20(2004), 12, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:20 year:2004 number:12 pages:0 http://dx.doi.org/10.1111/j.1460-9568.2004.03823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 12 0 |
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10.1111/j.1460-9568.2004.03823.x doi (DE-627)NLEJ242417094 DE-627 ger DE-627 rakwb Piché, Mathieu verfasserin aut Environmental enrichment enhances auditory takeover of the occipital cortex in anophthalmic mice Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| cross-modal compensation Robert, Stéphane verfasserin aut Miceli, Dom verfasserin aut Bronchti, Gilles oth In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 20(2004), 12, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:20 year:2004 number:12 pages:0 http://dx.doi.org/10.1111/j.1460-9568.2004.03823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 12 0 |
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10.1111/j.1460-9568.2004.03823.x doi (DE-627)NLEJ242417094 DE-627 ger DE-627 rakwb Piché, Mathieu verfasserin aut Environmental enrichment enhances auditory takeover of the occipital cortex in anophthalmic mice Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| cross-modal compensation Robert, Stéphane verfasserin aut Miceli, Dom verfasserin aut Bronchti, Gilles oth In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 20(2004), 12, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:20 year:2004 number:12 pages:0 http://dx.doi.org/10.1111/j.1460-9568.2004.03823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 20 2004 12 0 |
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Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. |
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Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. |
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Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. The present study used c-Fos immunohistochemistry and dextran–biotin neuronal tracing to examine the reorganization of sensory modalities in the brain of anophthalmic mutant mice (ZRDCT/An) raised in either enriched or standard environments. Auditory stimulation was found to elicit strong neuronal activation in thalamic and cortical structures that are normally visual. An important finding was that the latter auditory-evoked cortical activity was considerably enhanced in blind mice raised in the enriched environment. The axonal tracing study demonstrated auditory inputs from the inferior colliculus to the visual thalamus. This animal model will be useful for understanding neuronal mechanisms underlying some cross-modal sensory phenomena observed in blind or deaf humans. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242417094</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707154748.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2004 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1460-9568.2004.03823.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242417094</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Piché, Mathieu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Environmental enrichment enhances auditory takeover of the occipital cortex in anophthalmic mice</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Science Ltd</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Enrichment of the environment is an effective means of enhancing neuronal development and plasticity but its effect on the cross-modal compensation resulting from sensory deprivation has never been investigated. 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