Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates
We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. W...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Tehovnik, Edward J. [verfasserIn] Slocum, Warren M. [verfasserIn] Schiller, Peter H. [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Science Ltd ; 1999 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2008 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: European journal of neuroscience - Oxford [u.a.] : Blackwell, 1989, 11(1999), 7, Seite 0 |
| Übergeordnetes Werk: |
volume:11 ; year:1999 ; number:7 ; pages:0 |
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| DOI / URN: |
10.1046/j.1460-9568.1999.00665.x |
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| 520 | |a We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. | ||
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10.1046/j.1460-9568.1999.00665.x doi (DE-627)NLEJ242444261 DE-627 ger DE-627 rakwb Tehovnik, Edward J. verfasserin aut Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates Oxford, UK Blackwell Science Ltd 1999 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| behavioural state Slocum, Warren M. verfasserin aut Schiller, Peter H. verfasserin aut In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 11(1999), 7, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:11 year:1999 number:7 pages:0 http://dx.doi.org/10.1046/j.1460-9568.1999.00665.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 1999 7 0 |
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10.1046/j.1460-9568.1999.00665.x doi (DE-627)NLEJ242444261 DE-627 ger DE-627 rakwb Tehovnik, Edward J. verfasserin aut Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates Oxford, UK Blackwell Science Ltd 1999 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| behavioural state Slocum, Warren M. verfasserin aut Schiller, Peter H. verfasserin aut In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 11(1999), 7, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:11 year:1999 number:7 pages:0 http://dx.doi.org/10.1046/j.1460-9568.1999.00665.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 1999 7 0 |
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10.1046/j.1460-9568.1999.00665.x doi (DE-627)NLEJ242444261 DE-627 ger DE-627 rakwb Tehovnik, Edward J. verfasserin aut Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates Oxford, UK Blackwell Science Ltd 1999 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| behavioural state Slocum, Warren M. verfasserin aut Schiller, Peter H. verfasserin aut In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 11(1999), 7, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:11 year:1999 number:7 pages:0 http://dx.doi.org/10.1046/j.1460-9568.1999.00665.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 1999 7 0 |
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10.1046/j.1460-9568.1999.00665.x doi (DE-627)NLEJ242444261 DE-627 ger DE-627 rakwb Tehovnik, Edward J. verfasserin aut Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates Oxford, UK Blackwell Science Ltd 1999 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| behavioural state Slocum, Warren M. verfasserin aut Schiller, Peter H. verfasserin aut In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 11(1999), 7, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:11 year:1999 number:7 pages:0 http://dx.doi.org/10.1046/j.1460-9568.1999.00665.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 1999 7 0 |
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10.1046/j.1460-9568.1999.00665.x doi (DE-627)NLEJ242444261 DE-627 ger DE-627 rakwb Tehovnik, Edward J. verfasserin aut Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates Oxford, UK Blackwell Science Ltd 1999 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| behavioural state Slocum, Warren M. verfasserin aut Schiller, Peter H. verfasserin aut In European journal of neuroscience Oxford [u.a.] : Blackwell, 1989 11(1999), 7, Seite 0 Online-Ressource (DE-627)NLEJ243926383 (DE-600)2005178-5 1460-9568 nnns volume:11 year:1999 number:7 pages:0 http://dx.doi.org/10.1046/j.1460-9568.1999.00665.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 1999 7 0 |
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Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates |
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We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. |
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We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. |
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We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242444261</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707155204.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s1999 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1460-9568.1999.00665.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242444261</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Tehovnik, Edward J.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Science Ltd</subfield><subfield code="c">1999</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">We assessed the effects of varying the time at which electrical stimulation was delivered to the dorsomedial frontal cortex (DMFC) and the frontal eye fields (FEF) relative to the onset of a visual target. Monkeys were required to fixate the visual target to obtain a drop of apple juice as reward. We found that the probability of eliciting saccades increased with increases in the delay of electrical stimulation relative to target onset. Also, the current threshold to evoke saccades decreased as electrical stimulation was delivered later following target onset. There were major differences in the magnitude of this effect with stimulation of the DMFC versus the FEF. The current threshold to evoke saccades from the DMFC was 16 times greater when electrical stimulation was delivered 200 ms after target onset as compared to when it was delayed 200 ms after target offset. In contrast, the current threshold to evoke saccades from the FEFs was only three times greater when stimulation was delivered under similar conditions. These results suggest that the FEF are more closely connected with the saccade generator for the execution of saccadic eye movements than is the DMFC, even though both regions have direct projections to brainstem oculomotor centres.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2008</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2008||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">behavioural state</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Slocum, Warren M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schiller, Peter H.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">European journal of neuroscience</subfield><subfield code="d">Oxford [u.a.] : Blackwell, 1989</subfield><subfield code="g">11(1999), 7, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926383</subfield><subfield code="w">(DE-600)2005178-5</subfield><subfield code="x">1460-9568</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:11</subfield><subfield code="g">year:1999</subfield><subfield code="g">number:7</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1046/j.1460-9568.1999.00665.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">11</subfield><subfield code="j">1999</subfield><subfield code="e">7</subfield><subfield code="h">0</subfield></datafield></record></collection>
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