A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid
In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histolog...
Ausführliche Beschreibung
Autor*in: |
Dina, R. [verfasserIn] Capitanio, A. [verfasserIn] Damiani, S. [verfasserIn] |
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E-Artikel |
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Erschienen: |
Oxford, UK: Blackwell Science Ltd ; 2000 |
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Online-Ressource |
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Reproduktion: |
2001 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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Übergeordnetes Werk: |
In: Cytopathology - Oxford : Wiley-Blackwell, 1990, 11(2000), 2, Seite 0 |
Übergeordnetes Werk: |
volume:11 ; year:2000 ; number:2 ; pages:0 |
Links: |
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DOI / URN: |
10.1046/j.1365-2303.2000.00232.x |
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520 | |a In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. | ||
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10.1046/j.1365-2303.2000.00232.x doi (DE-627)NLEJ242489052 DE-627 ger DE-627 rakwb Dina, R. verfasserin aut A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| morphometry Capitanio, A. verfasserin aut Damiani, S. verfasserin aut In Cytopathology Oxford : Wiley-Blackwell, 1990 11(2000), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926294 (DE-600)2020042-0 1365-2303 nnns volume:11 year:2000 number:2 pages:0 http://dx.doi.org/10.1046/j.1365-2303.2000.00232.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 2 0 |
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10.1046/j.1365-2303.2000.00232.x doi (DE-627)NLEJ242489052 DE-627 ger DE-627 rakwb Dina, R. verfasserin aut A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| morphometry Capitanio, A. verfasserin aut Damiani, S. verfasserin aut In Cytopathology Oxford : Wiley-Blackwell, 1990 11(2000), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926294 (DE-600)2020042-0 1365-2303 nnns volume:11 year:2000 number:2 pages:0 http://dx.doi.org/10.1046/j.1365-2303.2000.00232.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 2 0 |
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10.1046/j.1365-2303.2000.00232.x doi (DE-627)NLEJ242489052 DE-627 ger DE-627 rakwb Dina, R. verfasserin aut A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| morphometry Capitanio, A. verfasserin aut Damiani, S. verfasserin aut In Cytopathology Oxford : Wiley-Blackwell, 1990 11(2000), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926294 (DE-600)2020042-0 1365-2303 nnns volume:11 year:2000 number:2 pages:0 http://dx.doi.org/10.1046/j.1365-2303.2000.00232.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 2 0 |
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10.1046/j.1365-2303.2000.00232.x doi (DE-627)NLEJ242489052 DE-627 ger DE-627 rakwb Dina, R. verfasserin aut A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| morphometry Capitanio, A. verfasserin aut Damiani, S. verfasserin aut In Cytopathology Oxford : Wiley-Blackwell, 1990 11(2000), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926294 (DE-600)2020042-0 1365-2303 nnns volume:11 year:2000 number:2 pages:0 http://dx.doi.org/10.1046/j.1365-2303.2000.00232.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 2 0 |
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10.1046/j.1365-2303.2000.00232.x doi (DE-627)NLEJ242489052 DE-627 ger DE-627 rakwb Dina, R. verfasserin aut A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid Oxford, UK Blackwell Science Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. 2001 Blackwell Publishing Journal Backfiles 1879-2005 |2001|||||||||| morphometry Capitanio, A. verfasserin aut Damiani, S. verfasserin aut In Cytopathology Oxford : Wiley-Blackwell, 1990 11(2000), 2, Seite 0 Online-Ressource (DE-627)NLEJ243926294 (DE-600)2020042-0 1365-2303 nnns volume:11 year:2000 number:2 pages:0 http://dx.doi.org/10.1046/j.1365-2303.2000.00232.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 2 0 |
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A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid |
abstract |
In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. |
abstractGer |
In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. |
abstract_unstemmed |
In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. The choice of simple morphometric parameters appears to be helpful in the preoperative distinction between the classical pattern and tall cell variant of papillary carcinoma. |
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Capitanio, A. Damiani, S. |
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NLEJ243926294 |
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doi_str |
10.1046/j.1365-2303.2000.00232.x |
up_date |
2024-07-06T02:10:18.717Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242489052</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707155838.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2000 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1046/j.1365-2303.2000.00232.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242489052</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Dina, R.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">A morphometric analysis of cytological features of tall cell variant and classical papillary carcinoma of the thyroid</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Science Ltd</subfield><subfield code="c">2000</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In order to assess whether morphometric parameters could be of value in distinguishing between tall cell variant and classical pattern of thyroid papillary carcinoma, the fine needle aspiration cytology (FNAC) samples of 14 cases were analysed using Arcimage 5 software on an Acorn computer. Histological examination of the specimens allowed classification of nine of them as classical pattern and the remaining five as tall cell variants. The nuclear diameter (NDD) and standard deviation distribution (NDSDD), the nuclear area (NAD) and standard deviation distribution (NASDD), and the nuclear/cytoplasmic ratio (NCR) were assessed on May-Grunwald-Giemsa stained smears. Statistical analysis was performed by use of one-way analysis of variance (anova) of the two groups as identified by histology. Whilst NDD (P= 0.007), NAD (P= 0.015) and NADSD (P= 0.026) all appeared statistically significant, NDSDD (P= 0.06) and NCR (P= 0.71) were not. The cytological diagnosis of papillary carcinoma is established and reproducible, but morphometric data on the thyroid have so far focused on the differential diagnosis between benign and malignant nodules. 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