Intravenous challenge with heparins in patients with delayed-type skin reactions after subcutaneous administration of the drug
Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation i...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Trautmann, Axel [verfasserIn] Brôcker, Eva-B. [verfasserIn] Klein, C. Eberhard [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|
| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1998 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2007 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Contact dermatitis - Oxford [u.a.] : Wiley-Blackwell, 1975, 39(1998), 1, Seite 0 |
| Übergeordnetes Werk: |
volume:39 ; year:1998 ; number:1 ; pages:0 |
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| DOI / URN: |
10.1111/j.1600-0536.1998.tb05823.x |
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| 520 | |a Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. | ||
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10.1111/j.1600-0536.1998.tb05823.x doi (DE-627)NLEJ24254438X DE-627 ger DE-627 rakwb Trautmann, Axel verfasserin aut Intravenous challenge with heparins in patients with delayed-type skin reactions after subcutaneous administration of the drug Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| heparin Brôcker, Eva-B. verfasserin aut Klein, C. Eberhard verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 39(1998), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:39 year:1998 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1998.tb05823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 39 1998 1 0 |
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10.1111/j.1600-0536.1998.tb05823.x doi (DE-627)NLEJ24254438X DE-627 ger DE-627 rakwb Trautmann, Axel verfasserin aut Intravenous challenge with heparins in patients with delayed-type skin reactions after subcutaneous administration of the drug Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| heparin Brôcker, Eva-B. verfasserin aut Klein, C. Eberhard verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 39(1998), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:39 year:1998 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1998.tb05823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 39 1998 1 0 |
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10.1111/j.1600-0536.1998.tb05823.x doi (DE-627)NLEJ24254438X DE-627 ger DE-627 rakwb Trautmann, Axel verfasserin aut Intravenous challenge with heparins in patients with delayed-type skin reactions after subcutaneous administration of the drug Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| heparin Brôcker, Eva-B. verfasserin aut Klein, C. Eberhard verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 39(1998), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:39 year:1998 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1998.tb05823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 39 1998 1 0 |
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10.1111/j.1600-0536.1998.tb05823.x doi (DE-627)NLEJ24254438X DE-627 ger DE-627 rakwb Trautmann, Axel verfasserin aut Intravenous challenge with heparins in patients with delayed-type skin reactions after subcutaneous administration of the drug Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| heparin Brôcker, Eva-B. verfasserin aut Klein, C. Eberhard verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 39(1998), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:39 year:1998 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1998.tb05823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 39 1998 1 0 |
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10.1111/j.1600-0536.1998.tb05823.x doi (DE-627)NLEJ24254438X DE-627 ger DE-627 rakwb Trautmann, Axel verfasserin aut Intravenous challenge with heparins in patients with delayed-type skin reactions after subcutaneous administration of the drug Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| heparin Brôcker, Eva-B. verfasserin aut Klein, C. Eberhard verfasserin aut In Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 39(1998), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927118 (DE-600)2027120-7 1600-0536 nnns volume:39 year:1998 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0536.1998.tb05823.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 39 1998 1 0 |
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| abstract |
Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. |
| abstractGer |
Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. |
| abstract_unstemmed |
Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ24254438X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230505183708.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s1998 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1600-0536.1998.tb05823.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ24254438X</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Trautmann, Axel</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Intravenous challenge with heparins in patients with delayed-type skin reactions after subcutaneous administration of the drug</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">1998</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Delayed-phase reactions after subcutaneous (s.c.) injection of high- or low-molecular-weight heparins are not rare. They present as indurated s.c. swelling with overlying erythema/eczema, causing burning or itching (1). Occasionally, an exanthematous reaction supervenes. If further anticoagulation is necessary, cross-reactivity with other anticoagulants (heparinoids), such as dermatan sulfate (OrgaranTM) or sodium pentosan polysulfate (FibrezymTM), is common (2). Even after the introduction of the new anticoagulant lepirudin (RefludanTM), heparins remain the drugs of choice, particularly for intravenous (i.v.) anticoagulation. The most important differential diagnosis from delayed-type reactions after s.c. heparin is the initial stage of heparin-induced skin necrosis, which may be a sign of heparin-induced thrombocytopenia (HIT). Cutaneous necrosis is characterized by a well-defined eschar surrounded by an inflammatory halo, and can occur either at the injection site or at distant sites.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2007</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2007||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">heparin</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brôcker, Eva-B.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Klein, C. 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7.399967 |