Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases
We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of d...
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| Autor*in: |
Morimitsu, Y. [verfasserIn] Hisaoka, M. [verfasserIn] Okamoto, S. [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, U.K. and Cambridge, USA: Blackwell Science Ltd ; 1998 |
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Online-Ressource |
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2002 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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In: Histopathology - Oxford [u.a.] : Wiley-Blackwell, 1977, 32(1998), 6, Seite 0 |
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volume:32 ; year:1998 ; number:6 ; pages:0 |
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| DOI / URN: |
10.1046/j.1365-2559.1998.00428.x |
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| 245 | 1 | 0 | |a Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases |
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| 520 | |a We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. | ||
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10.1046/j.1365-2559.1998.00428.x doi (DE-627)NLEJ24277444X DE-627 ger DE-627 rakwb Morimitsu, Y. verfasserin aut Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases Oxford, U.K. and Cambridge, USA Blackwell Science Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| dermatofibrosarcoma protuberans Hisaoka, M. verfasserin aut Okamoto, S. verfasserin aut Hashimoto, H. oth Ushijima, M. oth In Histopathology Oxford [u.a.] : Wiley-Blackwell, 1977 32(1998), 6, Seite 0 Online-Ressource (DE-627)NLEJ243927045 (DE-600)2006447-0 1365-2559 nnns volume:32 year:1998 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2559.1998.00428.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 1998 6 0 |
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10.1046/j.1365-2559.1998.00428.x doi (DE-627)NLEJ24277444X DE-627 ger DE-627 rakwb Morimitsu, Y. verfasserin aut Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases Oxford, U.K. and Cambridge, USA Blackwell Science Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| dermatofibrosarcoma protuberans Hisaoka, M. verfasserin aut Okamoto, S. verfasserin aut Hashimoto, H. oth Ushijima, M. oth In Histopathology Oxford [u.a.] : Wiley-Blackwell, 1977 32(1998), 6, Seite 0 Online-Ressource (DE-627)NLEJ243927045 (DE-600)2006447-0 1365-2559 nnns volume:32 year:1998 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2559.1998.00428.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 1998 6 0 |
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10.1046/j.1365-2559.1998.00428.x doi (DE-627)NLEJ24277444X DE-627 ger DE-627 rakwb Morimitsu, Y. verfasserin aut Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases Oxford, U.K. and Cambridge, USA Blackwell Science Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| dermatofibrosarcoma protuberans Hisaoka, M. verfasserin aut Okamoto, S. verfasserin aut Hashimoto, H. oth Ushijima, M. oth In Histopathology Oxford [u.a.] : Wiley-Blackwell, 1977 32(1998), 6, Seite 0 Online-Ressource (DE-627)NLEJ243927045 (DE-600)2006447-0 1365-2559 nnns volume:32 year:1998 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2559.1998.00428.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 1998 6 0 |
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10.1046/j.1365-2559.1998.00428.x doi (DE-627)NLEJ24277444X DE-627 ger DE-627 rakwb Morimitsu, Y. verfasserin aut Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases Oxford, U.K. and Cambridge, USA Blackwell Science Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| dermatofibrosarcoma protuberans Hisaoka, M. verfasserin aut Okamoto, S. verfasserin aut Hashimoto, H. oth Ushijima, M. oth In Histopathology Oxford [u.a.] : Wiley-Blackwell, 1977 32(1998), 6, Seite 0 Online-Ressource (DE-627)NLEJ243927045 (DE-600)2006447-0 1365-2559 nnns volume:32 year:1998 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2559.1998.00428.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 1998 6 0 |
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10.1046/j.1365-2559.1998.00428.x doi (DE-627)NLEJ24277444X DE-627 ger DE-627 rakwb Morimitsu, Y. verfasserin aut Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases Oxford, U.K. and Cambridge, USA Blackwell Science Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. 2002 Blackwell Publishing Journal Backfiles 1879-2005 |2002|||||||||| dermatofibrosarcoma protuberans Hisaoka, M. verfasserin aut Okamoto, S. verfasserin aut Hashimoto, H. oth Ushijima, M. oth In Histopathology Oxford [u.a.] : Wiley-Blackwell, 1977 32(1998), 6, Seite 0 Online-Ressource (DE-627)NLEJ243927045 (DE-600)2006447-0 1365-2559 nnns volume:32 year:1998 number:6 pages:0 http://dx.doi.org/10.1046/j.1365-2559.1998.00428.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 1998 6 0 |
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Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases |
| abstract |
We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. |
| abstractGer |
We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. |
| abstract_unstemmed |
We describe three examples of dermatofibrosarcoma protuberans which demonstrated focal myofibroblastic differentiation, and discuss the nature of myofibroblastic differentiation.<section xml:id="abs1-2"><title type="main">Methods and resultsWe studied three cases of dermatofibrosarcoma protuberans, two of which had fibrosarcomatous portions containing myoid areas, and one which showed myoid areas in ordinary dermatofibrosarcoma protuberans. Myoid areas were recognized histologically as randomly distributed, scattered bundles or small nodules of spindle cells with deeply eosinophilic cytoplasm. Myofibroblastic differentiation was demonstrated immunohistochemically by positive staining for smooth muscle actin and muscle-specific actin, and ultrastructurally by the presence of microfilament bundles with focal dense bodies and pinocytic vesicles. The myoid areas occasionally contained intraneoplastic blood vessels.<section xml:id="abs1-3"><title type="main">ConclusionThe presence of myoid areas may be related to reactive hyperplasia of stroma, and its relation to the histogenesis of dermatofibrosarcoma protuberans is uncertain. |
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Dermatofibrosarcoma protuberans and its fibrosarcomatous variant with areas of myoid differentiation: a report of three cases |
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