Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1
Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–...
Ausführliche Beschreibung
Autor*in: |
Morimoto, Y. [verfasserIn] Yoshioka, A. [verfasserIn] Imai, Y. [verfasserIn] |
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E-Artikel |
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Erschienen: |
Oxford, UK: Blackwell Science Ltd ; 2004 |
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Online-Ressource |
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2004 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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Übergeordnetes Werk: |
In: Haemophilia - Oxford [u.a.] : Wiley-Blackwell, 1995, 10(2004), 5, Seite 0 |
Übergeordnetes Werk: |
volume:10 ; year:2004 ; number:5 ; pages:0 |
Links: |
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DOI / URN: |
10.1111/j.1365-2516.2004.00914.x |
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NLEJ242800688 |
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520 | |a Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. | ||
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10.1111/j.1365-2516.2004.00914.x doi (DE-627)NLEJ242800688 DE-627 ger DE-627 rakwb Morimoto, Y. verfasserin aut Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1 Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| congenital α2-plasmin inhibitor deficiency Yoshioka, A. verfasserin aut Imai, Y. verfasserin aut Takahashi, Y. oth Minowa, H. oth Kirita, T. oth In Haemophilia Oxford [u.a.] : Wiley-Blackwell, 1995 10(2004), 5, Seite 0 Online-Ressource (DE-627)NLEJ243925867 (DE-600)2006344-1 1365-2516 nnns volume:10 year:2004 number:5 pages:0 http://dx.doi.org/10.1111/j.1365-2516.2004.00914.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 10 2004 5 0 |
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10.1111/j.1365-2516.2004.00914.x doi (DE-627)NLEJ242800688 DE-627 ger DE-627 rakwb Morimoto, Y. verfasserin aut Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1 Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| congenital α2-plasmin inhibitor deficiency Yoshioka, A. verfasserin aut Imai, Y. verfasserin aut Takahashi, Y. oth Minowa, H. oth Kirita, T. oth In Haemophilia Oxford [u.a.] : Wiley-Blackwell, 1995 10(2004), 5, Seite 0 Online-Ressource (DE-627)NLEJ243925867 (DE-600)2006344-1 1365-2516 nnns volume:10 year:2004 number:5 pages:0 http://dx.doi.org/10.1111/j.1365-2516.2004.00914.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 10 2004 5 0 |
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10.1111/j.1365-2516.2004.00914.x doi (DE-627)NLEJ242800688 DE-627 ger DE-627 rakwb Morimoto, Y. verfasserin aut Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1 Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| congenital α2-plasmin inhibitor deficiency Yoshioka, A. verfasserin aut Imai, Y. verfasserin aut Takahashi, Y. oth Minowa, H. oth Kirita, T. oth In Haemophilia Oxford [u.a.] : Wiley-Blackwell, 1995 10(2004), 5, Seite 0 Online-Ressource (DE-627)NLEJ243925867 (DE-600)2006344-1 1365-2516 nnns volume:10 year:2004 number:5 pages:0 http://dx.doi.org/10.1111/j.1365-2516.2004.00914.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 10 2004 5 0 |
allfieldsGer |
10.1111/j.1365-2516.2004.00914.x doi (DE-627)NLEJ242800688 DE-627 ger DE-627 rakwb Morimoto, Y. verfasserin aut Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1 Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| congenital α2-plasmin inhibitor deficiency Yoshioka, A. verfasserin aut Imai, Y. verfasserin aut Takahashi, Y. oth Minowa, H. oth Kirita, T. oth In Haemophilia Oxford [u.a.] : Wiley-Blackwell, 1995 10(2004), 5, Seite 0 Online-Ressource (DE-627)NLEJ243925867 (DE-600)2006344-1 1365-2516 nnns volume:10 year:2004 number:5 pages:0 http://dx.doi.org/10.1111/j.1365-2516.2004.00914.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 10 2004 5 0 |
allfieldsSound |
10.1111/j.1365-2516.2004.00914.x doi (DE-627)NLEJ242800688 DE-627 ger DE-627 rakwb Morimoto, Y. verfasserin aut Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1 Oxford, UK Blackwell Science Ltd 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| congenital α2-plasmin inhibitor deficiency Yoshioka, A. verfasserin aut Imai, Y. verfasserin aut Takahashi, Y. oth Minowa, H. oth Kirita, T. oth In Haemophilia Oxford [u.a.] : Wiley-Blackwell, 1995 10(2004), 5, Seite 0 Online-Ressource (DE-627)NLEJ243925867 (DE-600)2006344-1 1365-2516 nnns volume:10 year:2004 number:5 pages:0 http://dx.doi.org/10.1111/j.1365-2516.2004.00914.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 10 2004 5 0 |
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Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. 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Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1 |
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Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. |
abstractGer |
Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. |
abstract_unstemmed |
Summary. Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone. |
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title_short |
Haemostatic management of intraoral bleeding in patients with congenital deficiency of α2-plasmin inhibitor or plasminogen activator inhibitor-1 |
url |
http://dx.doi.org/10.1111/j.1365-2516.2004.00914.x |
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Yoshioka, A. Imai, Y. Takahashi, Y. Minowa, H. Kirita, T. |
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