Irritation and cytotoxic potential of denture adhesives
Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Al, Ronald H. [verfasserIn] Dahl, Jon E. [verfasserIn] Morisbak, Else [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 2005 |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2005 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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In: Gerodontology - [S.l.] : Wiley-Blackwell, 1982, 22(2005), 3, Seite 0 |
| Übergeordnetes Werk: |
volume:22 ; year:2005 ; number:3 ; pages:0 |
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| DOI / URN: |
10.1111/j.1741-2358.2005.00073.x |
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NLEJ242836607 |
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| 245 | 1 | 0 | |a Irritation and cytotoxic potential of denture adhesives |
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| 520 | |a Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. | ||
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10.1111/j.1741-2358.2005.00073.x doi (DE-627)NLEJ242836607 DE-627 ger DE-627 rakwb Al, Ronald H. verfasserin aut Irritation and cytotoxic potential of denture adhesives Oxford, UK Blackwell Publishing Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| biocompatibility Dahl, Jon E. verfasserin aut Morisbak, Else verfasserin aut Polyzois, Gregory L. oth In Gerodontology [S.l.] : Wiley-Blackwell, 1982 22(2005), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926790 (DE-600)2133401-8 1741-2358 nnns volume:22 year:2005 number:3 pages:0 http://dx.doi.org/10.1111/j.1741-2358.2005.00073.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 2005 3 0 |
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10.1111/j.1741-2358.2005.00073.x doi (DE-627)NLEJ242836607 DE-627 ger DE-627 rakwb Al, Ronald H. verfasserin aut Irritation and cytotoxic potential of denture adhesives Oxford, UK Blackwell Publishing Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| biocompatibility Dahl, Jon E. verfasserin aut Morisbak, Else verfasserin aut Polyzois, Gregory L. oth In Gerodontology [S.l.] : Wiley-Blackwell, 1982 22(2005), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926790 (DE-600)2133401-8 1741-2358 nnns volume:22 year:2005 number:3 pages:0 http://dx.doi.org/10.1111/j.1741-2358.2005.00073.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 2005 3 0 |
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10.1111/j.1741-2358.2005.00073.x doi (DE-627)NLEJ242836607 DE-627 ger DE-627 rakwb Al, Ronald H. verfasserin aut Irritation and cytotoxic potential of denture adhesives Oxford, UK Blackwell Publishing Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| biocompatibility Dahl, Jon E. verfasserin aut Morisbak, Else verfasserin aut Polyzois, Gregory L. oth In Gerodontology [S.l.] : Wiley-Blackwell, 1982 22(2005), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926790 (DE-600)2133401-8 1741-2358 nnns volume:22 year:2005 number:3 pages:0 http://dx.doi.org/10.1111/j.1741-2358.2005.00073.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 2005 3 0 |
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10.1111/j.1741-2358.2005.00073.x doi (DE-627)NLEJ242836607 DE-627 ger DE-627 rakwb Al, Ronald H. verfasserin aut Irritation and cytotoxic potential of denture adhesives Oxford, UK Blackwell Publishing Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| biocompatibility Dahl, Jon E. verfasserin aut Morisbak, Else verfasserin aut Polyzois, Gregory L. oth In Gerodontology [S.l.] : Wiley-Blackwell, 1982 22(2005), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926790 (DE-600)2133401-8 1741-2358 nnns volume:22 year:2005 number:3 pages:0 http://dx.doi.org/10.1111/j.1741-2358.2005.00073.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 2005 3 0 |
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10.1111/j.1741-2358.2005.00073.x doi (DE-627)NLEJ242836607 DE-627 ger DE-627 rakwb Al, Ronald H. verfasserin aut Irritation and cytotoxic potential of denture adhesives Oxford, UK Blackwell Publishing Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| biocompatibility Dahl, Jon E. verfasserin aut Morisbak, Else verfasserin aut Polyzois, Gregory L. oth In Gerodontology [S.l.] : Wiley-Blackwell, 1982 22(2005), 3, Seite 0 Online-Ressource (DE-627)NLEJ243926790 (DE-600)2133401-8 1741-2358 nnns volume:22 year:2005 number:3 pages:0 http://dx.doi.org/10.1111/j.1741-2358.2005.00073.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 22 2005 3 0 |
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Irritation and cytotoxic potential of denture adhesives |
| abstract |
Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. |
| abstractGer |
Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. |
| abstract_unstemmed |
Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers. |
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Irritation and cytotoxic potential of denture adhesives |
| url |
http://dx.doi.org/10.1111/j.1741-2358.2005.00073.x |
| remote_bool |
true |
| author2 |
Dahl, Jon E. Morisbak, Else Polyzois, Gregory L. |
| author2Str |
Dahl, Jon E. Morisbak, Else Polyzois, Gregory L. |
| ppnlink |
NLEJ243926790 |
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z |
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false |
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false |
| author2_role |
oth |
| doi_str |
10.1111/j.1741-2358.2005.00073.x |
| up_date |
2024-07-06T03:21:18.838Z |
| _version_ |
1803798266603634688 |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ242836607</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707164753.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2005 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1741-2358.2005.00073.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ242836607</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Al, Ronald H.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Irritation and cytotoxic potential of denture adhesives</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing Ltd</subfield><subfield code="c">2005</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective: The present study aimed to examine the in vitro biocompatibility of denture adhesives.Background: Denture adhesives absorb water to become viscous and sticky, and by this process, other constituents like colouring, flavouring, wetting and preserving agents may be released. Some of these constituents may induce adverse reactions among users of denture adhesives.Materials and methods: Five commercially available denture adhesives; three different creams, a powder, and a cushion were included in the study. The irritation and cytotoxic potential was evaluated using the Hen's Egg Test Chorioallantoic Membrane (HET-CAM) method and three cell culture methods; filter diffusion, dimethylthiazol diphenyltetrazolium bromide (MTT) assay and agar diffusion.Results: None of the tested denture adhesives showed a noteworthy acute irritation as evaluated by the HET-CAM method. None of the tested denture adhesives induced cytotoxicity in the filter diffusion test. One of the denture adhesives induced a severe cytotoxic reaction in both the MTT and agar diffusion assays. These tests employ longer exposure times than in both the filter diffusion and the HET-CAM test.Conclusion: Denture adhesives are commonly used throughout the day, and our results raise the concern that denture adhesives may contribute to mucosal inflammation in denture wearers.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2005</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2005||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">biocompatibility</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dahl, Jon E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Morisbak, Else</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Polyzois, Gregory L.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Gerodontology</subfield><subfield code="d">[S.l.] : Wiley-Blackwell, 1982</subfield><subfield code="g">22(2005), 3, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926790</subfield><subfield code="w">(DE-600)2133401-8</subfield><subfield code="x">1741-2358</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:22</subfield><subfield code="g">year:2005</subfield><subfield code="g">number:3</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1741-2358.2005.00073.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">22</subfield><subfield code="j">2005</subfield><subfield code="e">3</subfield><subfield code="h">0</subfield></datafield></record></collection>
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7.3973093 |