MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement
Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement a...
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Gespeichert in:
| Autor*in: |
Tiilikainen, P. [verfasserIn] Pirttiniemi, P. [verfasserIn] Kainulainen, T. [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Munksgaard International Publishers ; 2005 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2004 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Journal of oral pathology & medicine - Oxford [u.a.] : Wiley-Blackwell, 1972, 34(2005), 1, Seite 0 |
| Übergeordnetes Werk: |
volume:34 ; year:2005 ; number:1 ; pages:0 |
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| DOI / URN: |
10.1111/j.1600-0714.2004.00262.x |
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NLEJ243033877 |
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| 245 | 1 | 0 | |a MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement |
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| 520 | |a Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. | ||
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| 700 | 1 | |a Raustia, A. |4 oth | |
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10.1111/j.1600-0714.2004.00262.x doi (DE-627)NLEJ243033877 DE-627 ger DE-627 rakwb Tiilikainen, P. verfasserin aut MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement Oxford, UK Munksgaard International Publishers 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| internal derangement Pirttiniemi, P. verfasserin aut Kainulainen, T. verfasserin aut Pernu, H. oth Raustia, A. oth In Journal of oral pathology & medicine Oxford [u.a.] : Wiley-Blackwell, 1972 34(2005), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927231 (DE-600)2026385-5 1600-0714 nnns volume:34 year:2005 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0714.2004.00262.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 34 2005 1 0 |
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10.1111/j.1600-0714.2004.00262.x doi (DE-627)NLEJ243033877 DE-627 ger DE-627 rakwb Tiilikainen, P. verfasserin aut MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement Oxford, UK Munksgaard International Publishers 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| internal derangement Pirttiniemi, P. verfasserin aut Kainulainen, T. verfasserin aut Pernu, H. oth Raustia, A. oth In Journal of oral pathology & medicine Oxford [u.a.] : Wiley-Blackwell, 1972 34(2005), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927231 (DE-600)2026385-5 1600-0714 nnns volume:34 year:2005 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0714.2004.00262.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 34 2005 1 0 |
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10.1111/j.1600-0714.2004.00262.x doi (DE-627)NLEJ243033877 DE-627 ger DE-627 rakwb Tiilikainen, P. verfasserin aut MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement Oxford, UK Munksgaard International Publishers 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| internal derangement Pirttiniemi, P. verfasserin aut Kainulainen, T. verfasserin aut Pernu, H. oth Raustia, A. oth In Journal of oral pathology & medicine Oxford [u.a.] : Wiley-Blackwell, 1972 34(2005), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927231 (DE-600)2026385-5 1600-0714 nnns volume:34 year:2005 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0714.2004.00262.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 34 2005 1 0 |
| allfieldsGer |
10.1111/j.1600-0714.2004.00262.x doi (DE-627)NLEJ243033877 DE-627 ger DE-627 rakwb Tiilikainen, P. verfasserin aut MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement Oxford, UK Munksgaard International Publishers 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| internal derangement Pirttiniemi, P. verfasserin aut Kainulainen, T. verfasserin aut Pernu, H. oth Raustia, A. oth In Journal of oral pathology & medicine Oxford [u.a.] : Wiley-Blackwell, 1972 34(2005), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927231 (DE-600)2026385-5 1600-0714 nnns volume:34 year:2005 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0714.2004.00262.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 34 2005 1 0 |
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10.1111/j.1600-0714.2004.00262.x doi (DE-627)NLEJ243033877 DE-627 ger DE-627 rakwb Tiilikainen, P. verfasserin aut MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement Oxford, UK Munksgaard International Publishers 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. 2004 Blackwell Publishing Journal Backfiles 1879-2005 |2004|||||||||| internal derangement Pirttiniemi, P. verfasserin aut Kainulainen, T. verfasserin aut Pernu, H. oth Raustia, A. oth In Journal of oral pathology & medicine Oxford [u.a.] : Wiley-Blackwell, 1972 34(2005), 1, Seite 0 Online-Ressource (DE-627)NLEJ243927231 (DE-600)2026385-5 1600-0714 nnns volume:34 year:2005 number:1 pages:0 http://dx.doi.org/10.1111/j.1600-0714.2004.00262.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 34 2005 1 0 |
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The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2004</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2004||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">internal derangement</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pirttiniemi, P.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kainulainen, T.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pernu, H.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Raustia, A.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of oral pathology & medicine</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1972</subfield><subfield code="g">34(2005), 1, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243927231</subfield><subfield code="w">(DE-600)2026385-5</subfield><subfield code="x">1600-0714</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:34</subfield><subfield code="g">year:2005</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1111/j.1600-0714.2004.00262.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">34</subfield><subfield code="j">2005</subfield><subfield code="e">1</subfield><subfield code="h">0</subfield></datafield></record></collection>
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MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement |
| abstract |
Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. |
| abstractGer |
Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. |
| abstract_unstemmed |
Background: Internal derangement is one of the most common disorder of the temporomandibular joint (TMJ). The aim of this study was to investigate the associations of matrix metalloproteinase (MMP)-3 and -8 expression in articular condylar surface with different stages of TMJ internal derangement according to Wilkes (Minn Med, 1978; 61: 645–52) and osteoarthrosis (OA) according to Dijkgraaf et al. (J Oral Maxillofac Surg, 1995; 53: 1182–92).Methods: The study was based on 54 condylar specimens obtained during TMJ surgery. Immunohistochemistry using antibodies specific to MMP-3 and -8, represented in cartilage destruction, was carried out.Results: In all tissue specimens, MMP-3 expression was intense in the surface layer but showed less intensive staining in the deeper layers. Some MMP-8 expression was also seen. The severity of TMJ internal derangement, however, did not seem to have a statistically significant correlation (P < 0.05) with the expression of these enzymes.Conclusion: The study confirms that distinct expression of MMP-3 and -8 is found in the condylar surface of TMJs with internal derangement. |
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MMP-3 and -8 expression is found in the condylar surface of temporomandibular joints with internal derangement |
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Pirttiniemi, P. Kainulainen, T. Pernu, H. Raustia, A. |
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