Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial
summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment fo...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
AARAB, G. [verfasserIn] LOBBEZOO, F. [verfasserIn] WICKS, D. J. [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Science Ltd ; 2005 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2005 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Journal of oral rehabilitation - Oxford [u.a.] : Wiley-Blackwell, 1974, 32(2005), 8, Seite 0 |
| Übergeordnetes Werk: |
volume:32 ; year:2005 ; number:8 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1111/j.1365-2842.2005.01467.x |
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NLEJ243041683 |
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| 520 | |a summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. | ||
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10.1111/j.1365-2842.2005.01467.x doi (DE-627)NLEJ243041683 DE-627 ger DE-627 rakwb AARAB, G. verfasserin aut Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial Oxford, UK Blackwell Science Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| obstructive sleep apnoea LOBBEZOO, F. verfasserin aut WICKS, D. J. verfasserin aut HAMBURGER, H. L. oth NAEIJE, M. oth In Journal of oral rehabilitation Oxford [u.a.] : Wiley-Blackwell, 1974 32(2005), 8, Seite 0 Online-Ressource (DE-627)NLEJ243927177 (DE-600)2007587-X 1365-2842 nnns volume:32 year:2005 number:8 pages:0 http://dx.doi.org/10.1111/j.1365-2842.2005.01467.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 2005 8 0 |
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10.1111/j.1365-2842.2005.01467.x doi (DE-627)NLEJ243041683 DE-627 ger DE-627 rakwb AARAB, G. verfasserin aut Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial Oxford, UK Blackwell Science Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| obstructive sleep apnoea LOBBEZOO, F. verfasserin aut WICKS, D. J. verfasserin aut HAMBURGER, H. L. oth NAEIJE, M. oth In Journal of oral rehabilitation Oxford [u.a.] : Wiley-Blackwell, 1974 32(2005), 8, Seite 0 Online-Ressource (DE-627)NLEJ243927177 (DE-600)2007587-X 1365-2842 nnns volume:32 year:2005 number:8 pages:0 http://dx.doi.org/10.1111/j.1365-2842.2005.01467.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 2005 8 0 |
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10.1111/j.1365-2842.2005.01467.x doi (DE-627)NLEJ243041683 DE-627 ger DE-627 rakwb AARAB, G. verfasserin aut Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial Oxford, UK Blackwell Science Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| obstructive sleep apnoea LOBBEZOO, F. verfasserin aut WICKS, D. J. verfasserin aut HAMBURGER, H. L. oth NAEIJE, M. oth In Journal of oral rehabilitation Oxford [u.a.] : Wiley-Blackwell, 1974 32(2005), 8, Seite 0 Online-Ressource (DE-627)NLEJ243927177 (DE-600)2007587-X 1365-2842 nnns volume:32 year:2005 number:8 pages:0 http://dx.doi.org/10.1111/j.1365-2842.2005.01467.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 2005 8 0 |
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10.1111/j.1365-2842.2005.01467.x doi (DE-627)NLEJ243041683 DE-627 ger DE-627 rakwb AARAB, G. verfasserin aut Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial Oxford, UK Blackwell Science Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| obstructive sleep apnoea LOBBEZOO, F. verfasserin aut WICKS, D. J. verfasserin aut HAMBURGER, H. L. oth NAEIJE, M. oth In Journal of oral rehabilitation Oxford [u.a.] : Wiley-Blackwell, 1974 32(2005), 8, Seite 0 Online-Ressource (DE-627)NLEJ243927177 (DE-600)2007587-X 1365-2842 nnns volume:32 year:2005 number:8 pages:0 http://dx.doi.org/10.1111/j.1365-2842.2005.01467.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 2005 8 0 |
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10.1111/j.1365-2842.2005.01467.x doi (DE-627)NLEJ243041683 DE-627 ger DE-627 rakwb AARAB, G. verfasserin aut Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial Oxford, UK Blackwell Science Ltd 2005 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| obstructive sleep apnoea LOBBEZOO, F. verfasserin aut WICKS, D. J. verfasserin aut HAMBURGER, H. L. oth NAEIJE, M. oth In Journal of oral rehabilitation Oxford [u.a.] : Wiley-Blackwell, 1974 32(2005), 8, Seite 0 Online-Ressource (DE-627)NLEJ243927177 (DE-600)2007587-X 1365-2842 nnns volume:32 year:2005 number:8 pages:0 http://dx.doi.org/10.1111/j.1365-2842.2005.01467.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 32 2005 8 0 |
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short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial |
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Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial |
| abstract |
summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. |
| abstractGer |
summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. |
| abstract_unstemmed |
summary Obstructive sleep apnoea (OSA) is a common sleep disorder, which is, among others, associated with snoring. OSA has a considerable impact on a patient's general health and daily life. Nasal continuous positive airway pressure (nCPAP) is frequently used as a ‘gold standard’ treatment for OSA. As an alternative, especially for mild/moderate cases, mandibular advancement devices (MADs) are prescribed increasingly. Their efficacy and effectiveness seem to be acceptable. Although some randomized clinical trials (RCTs) have been published recently, most studies so far are case studies. Therefore, our department is planning a controlled RCT, in which MADs are compared with both nCPAP and a control condition in a parallel design. As a first step, an adjustable MAD was developed with a small, more or less constant vertical dimension at different mandibular positions. To test the device and the experimental procedures, a pilot trial was performed with 10 OSA patients (six mild, four moderate; one women, nine men; mean age = 47·9 ± 9·7 years). They all underwent a polysomnographic recording before as well as 2–14 weeks after insertion of the MAD (adjusted at 50% of the maximal protrusion). The apnoea–hypopnoea index (AHI) was significantly reduced with the MAD in situ (P = 0·017). When analysed as separate groups, the moderate cases showed a significantly larger decrease in AHI than the mild cases (P = 0·012). It was therefore concluded from this pilot study that this MAD might be an effective tool in the treatment of, especially, moderate OSA. |
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| title_short |
Short-term effects of a mandibular advancement device on obstructive sleep apnoea: an open-label pilot trial |
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http://dx.doi.org/10.1111/j.1365-2842.2005.01467.x |
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LOBBEZOO, F. WICKS, D. J. HAMBURGER, H. L. NAEIJE, M. |
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LOBBEZOO, F. WICKS, D. J. HAMBURGER, H. L. NAEIJE, M. |
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| doi_str |
10.1111/j.1365-2842.2005.01467.x |
| up_date |
2024-07-06T04:04:49.104Z |
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