Local delivery of chemotherapeutic agents in periodontal therapy: Has its time arrived?
Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigatio...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Finkelman, Richard D. [verfasserIn] Williams, Ray C. [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1998 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2005 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Journal of clinical periodontology - Oxford [u.a.] : Wiley-Blackwell, 1974, 25(1998), 11, Seite 0 |
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volume:25 ; year:1998 ; number:11 ; pages:0 |
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| DOI / URN: |
10.1111/j.1600-051X.1998.tb02395.x |
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| 520 | |a Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. | ||
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10.1111/j.1600-051X.1998.tb02395.x doi (DE-627)NLEJ243332610 DE-627 ger DE-627 rakwb Finkelman, Richard D. verfasserin aut Local delivery of chemotherapeutic agents in periodontal therapy: Has its time arrived? Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| anti-infective agents Williams, Ray C. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 25(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:25 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1998.tb02395.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 25 1998 11 0 |
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10.1111/j.1600-051X.1998.tb02395.x doi (DE-627)NLEJ243332610 DE-627 ger DE-627 rakwb Finkelman, Richard D. verfasserin aut Local delivery of chemotherapeutic agents in periodontal therapy: Has its time arrived? Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| anti-infective agents Williams, Ray C. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 25(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:25 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1998.tb02395.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 25 1998 11 0 |
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10.1111/j.1600-051X.1998.tb02395.x doi (DE-627)NLEJ243332610 DE-627 ger DE-627 rakwb Finkelman, Richard D. verfasserin aut Local delivery of chemotherapeutic agents in periodontal therapy: Has its time arrived? Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| anti-infective agents Williams, Ray C. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 25(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:25 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1998.tb02395.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 25 1998 11 0 |
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10.1111/j.1600-051X.1998.tb02395.x doi (DE-627)NLEJ243332610 DE-627 ger DE-627 rakwb Finkelman, Richard D. verfasserin aut Local delivery of chemotherapeutic agents in periodontal therapy: Has its time arrived? Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| anti-infective agents Williams, Ray C. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 25(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:25 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1998.tb02395.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 25 1998 11 0 |
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10.1111/j.1600-051X.1998.tb02395.x doi (DE-627)NLEJ243332610 DE-627 ger DE-627 rakwb Finkelman, Richard D. verfasserin aut Local delivery of chemotherapeutic agents in periodontal therapy: Has its time arrived? Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. 2005 Blackwell Publishing Journal Backfiles 1879-2005 |2005|||||||||| anti-infective agents Williams, Ray C. verfasserin aut In Journal of clinical periodontology Oxford [u.a.] : Wiley-Blackwell, 1974 25(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243927142 (DE-600)2026349-1 1600-051X nnns volume:25 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1600-051X.1998.tb02395.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 25 1998 11 0 |
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Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. |
| abstractGer |
Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. |
| abstract_unstemmed |
Abstract. The concept of locally-delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally-delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives from sustained-release technology to maintain an effective concentration of drug within the periodontal pocket for a clinically relevant length of time. Studied drugs have mainly been antimicrobials, both antibiotics and antiseptics. Most agents have been tested as adjuncts to scaling and root planing: a few have been studied as stand-alone monotherapies. Collectively, the data indicate that the use of locally-delivered antimicrobials as adjuncts results in a significant increase in the reduction of probing depth compared with scaling and root planing alone. In other trials, results in reducing probing depth following the use of stand-alone locally-delivered antimicrobials have been equivalent to those of scaling and root planing over a specified time. This Symposium was organized to present the current slate-of-the-art with regard to the use of locally delivered antimicrobials in the treatment of periodontal disease, 5 experts in the field who have had considerable experience in studying locally-delivered antimicrobials presented data. These speakers reviewed the clinical findings regarding efficacy of 5 different antimicrobial agents. An ensuing panel discussion was to consider treatment recommendations for locally-delivered antimicrobials. |
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Local delivery of chemotherapeutic agents in periodontal therapy: Has its time arrived? |
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