Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function
RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a bia...
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THOMAS, STUART P. - B.MED., FRACP [verfasserIn] NICHOLSON, IAN A. - M.B.B.S., FRACS [verfasserIn] NUNN, GRAHAM R. - M.B.B.S., FRACS [verfasserIn] REES, ARIANWEN - B.Sc. TRIEU, LAWRENCE - B.Sc., MED DALY, MICHAEL P.J. - B.ENG., Ph.D. WALLACE, ELISABETH M. - B.Sc. ROSS, DAVID L. - M.B.B.S., FRACP |
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E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 2000 |
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Online-Ressource |
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| Reproduktion: |
2007 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Journal of cardiovascular electrophysiology - Oxford : Wiley-Blackwell, 1990, 11(2000), 1, Seite 0 |
| Übergeordnetes Werk: |
volume:11 ; year:2000 ; number:1 ; pages:0 |
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| DOI / URN: |
10.1111/j.1540-8167.2000.tb00740.x |
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NLEJ243360487 |
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| 245 | 1 | 0 | |a Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function |
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| 520 | |a RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. | ||
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| 700 | 1 | |a NICHOLSON, IAN A. |c M.B.B.S., FRACS |e verfasserin |4 aut | |
| 700 | 1 | |a NUNN, GRAHAM R. |c M.B.B.S., FRACS |e verfasserin |4 aut | |
| 700 | 1 | |a REES, ARIANWEN |c B.Sc. |4 oth | |
| 700 | 1 | |a TRIEU, LAWRENCE |c B.Sc., MED |4 oth | |
| 700 | 1 | |a DALY, MICHAEL P.J. |c B.ENG., Ph.D. |4 oth | |
| 700 | 1 | |a WALLACE, ELISABETH M. |c B.Sc. |4 oth | |
| 700 | 1 | |a ROSS, DAVID L. |c M.B.B.S., FRACP |4 oth | |
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10.1111/j.1540-8167.2000.tb00740.x doi (DE-627)NLEJ243360487 DE-627 ger DE-627 rakwb THOMAS, STUART P. B.MED., FRACP verfasserin aut Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function Oxford, UK Blackwell Publishing Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| ablation NICHOLSON, IAN A. M.B.B.S., FRACS verfasserin aut NUNN, GRAHAM R. M.B.B.S., FRACS verfasserin aut REES, ARIANWEN B.Sc. oth TRIEU, LAWRENCE B.Sc., MED oth DALY, MICHAEL P.J. B.ENG., Ph.D. oth WALLACE, ELISABETH M. B.Sc. oth ROSS, DAVID L. M.B.B.S., FRACP oth In Journal of cardiovascular electrophysiology Oxford : Wiley-Blackwell, 1990 11(2000), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926243 (DE-600)2037519-0 1540-8167 nnns volume:11 year:2000 number:1 pages:0 http://dx.doi.org/10.1111/j.1540-8167.2000.tb00740.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 1 0 |
| spelling |
10.1111/j.1540-8167.2000.tb00740.x doi (DE-627)NLEJ243360487 DE-627 ger DE-627 rakwb THOMAS, STUART P. B.MED., FRACP verfasserin aut Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function Oxford, UK Blackwell Publishing Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| ablation NICHOLSON, IAN A. M.B.B.S., FRACS verfasserin aut NUNN, GRAHAM R. M.B.B.S., FRACS verfasserin aut REES, ARIANWEN B.Sc. oth TRIEU, LAWRENCE B.Sc., MED oth DALY, MICHAEL P.J. B.ENG., Ph.D. oth WALLACE, ELISABETH M. B.Sc. oth ROSS, DAVID L. M.B.B.S., FRACP oth In Journal of cardiovascular electrophysiology Oxford : Wiley-Blackwell, 1990 11(2000), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926243 (DE-600)2037519-0 1540-8167 nnns volume:11 year:2000 number:1 pages:0 http://dx.doi.org/10.1111/j.1540-8167.2000.tb00740.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 1 0 |
| allfields_unstemmed |
10.1111/j.1540-8167.2000.tb00740.x doi (DE-627)NLEJ243360487 DE-627 ger DE-627 rakwb THOMAS, STUART P. B.MED., FRACP verfasserin aut Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function Oxford, UK Blackwell Publishing Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| ablation NICHOLSON, IAN A. M.B.B.S., FRACS verfasserin aut NUNN, GRAHAM R. M.B.B.S., FRACS verfasserin aut REES, ARIANWEN B.Sc. oth TRIEU, LAWRENCE B.Sc., MED oth DALY, MICHAEL P.J. B.ENG., Ph.D. oth WALLACE, ELISABETH M. B.Sc. oth ROSS, DAVID L. M.B.B.S., FRACP oth In Journal of cardiovascular electrophysiology Oxford : Wiley-Blackwell, 1990 11(2000), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926243 (DE-600)2037519-0 1540-8167 nnns volume:11 year:2000 number:1 pages:0 http://dx.doi.org/10.1111/j.1540-8167.2000.tb00740.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 1 0 |
| allfieldsGer |
10.1111/j.1540-8167.2000.tb00740.x doi (DE-627)NLEJ243360487 DE-627 ger DE-627 rakwb THOMAS, STUART P. B.MED., FRACP verfasserin aut Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function Oxford, UK Blackwell Publishing Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| ablation NICHOLSON, IAN A. M.B.B.S., FRACS verfasserin aut NUNN, GRAHAM R. M.B.B.S., FRACS verfasserin aut REES, ARIANWEN B.Sc. oth TRIEU, LAWRENCE B.Sc., MED oth DALY, MICHAEL P.J. B.ENG., Ph.D. oth WALLACE, ELISABETH M. B.Sc. oth ROSS, DAVID L. M.B.B.S., FRACP oth In Journal of cardiovascular electrophysiology Oxford : Wiley-Blackwell, 1990 11(2000), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926243 (DE-600)2037519-0 1540-8167 nnns volume:11 year:2000 number:1 pages:0 http://dx.doi.org/10.1111/j.1540-8167.2000.tb00740.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 1 0 |
| allfieldsSound |
10.1111/j.1540-8167.2000.tb00740.x doi (DE-627)NLEJ243360487 DE-627 ger DE-627 rakwb THOMAS, STUART P. B.MED., FRACP verfasserin aut Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function Oxford, UK Blackwell Publishing Ltd 2000 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. 2007 Blackwell Publishing Journal Backfiles 1879-2005 |2007|||||||||| ablation NICHOLSON, IAN A. M.B.B.S., FRACS verfasserin aut NUNN, GRAHAM R. M.B.B.S., FRACS verfasserin aut REES, ARIANWEN B.Sc. oth TRIEU, LAWRENCE B.Sc., MED oth DALY, MICHAEL P.J. B.ENG., Ph.D. oth WALLACE, ELISABETH M. B.Sc. oth ROSS, DAVID L. M.B.B.S., FRACP oth In Journal of cardiovascular electrophysiology Oxford : Wiley-Blackwell, 1990 11(2000), 1, Seite 0 Online-Ressource (DE-627)NLEJ243926243 (DE-600)2037519-0 1540-8167 nnns volume:11 year:2000 number:1 pages:0 http://dx.doi.org/10.1111/j.1540-8167.2000.tb00740.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 11 2000 1 0 |
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THOMAS, STUART P. @@aut@@ NICHOLSON, IAN A. @@aut@@ NUNN, GRAHAM R. @@aut@@ REES, ARIANWEN @@oth@@ TRIEU, LAWRENCE @@oth@@ DALY, MICHAEL P.J. @@oth@@ WALLACE, ELISABETH M. @@oth@@ ROSS, DAVID L. @@oth@@ |
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Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. 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Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function ablation |
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effect of atrial radiofrequency ablation designed to cure atrial fibrillation on atrial mechanical function |
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Effect of Atrial Radiofrequency Ablation Designed to Cure Atrial Fibrillation on Atrial Mechanical Function |
| abstract |
RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. |
| abstractGer |
RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. |
| abstract_unstemmed |
RF Ablation for AF and Atrial Contractile Function. Introduction: The effects of linear radiofrequency lesions in the atria for cure of atrial fibrillation on atrial contraction have not previously been quantified. Methods and Results: Atrial function was measured before and 30 ± 24 days after a biatrial ablation procedure designed to cure atrial fibrillation in eight dogs and after a sham procedure in three dogs. Atrial mechanical function was assessed using Doppler diastolic blood flow velocities, atrial systolic pressure wave amplitude, and assessment of atrial contribution to cardiac output estimated by comparison of AV sequential pacing to ventricular pacing at the same heart rate. The mitral Doppler A/E velocity ratio was 1.03 ± 0.45 before and 0.72 ± 0.43 after ablation (P = 0.048). The tricuspid A/E ratio was 0.88 ± 0.17 before and 0.71 ± 0.12 after ablation (P = 0.04). The estimated atrial contribution to cardiac output was 18%± 9% before and 5%± 4% after ablation (P < 0.01). The left atrial systolic pressure wave amplitude was 2.8 ± 1.5 mmHg before and 1.7 ± 1.0 mmHg after ablation (P = 0.1). These changes were not observed in control dogs. Lesions covered 25%± 6% of tbe atrial endocardia) surface. Conclusion: Multiple linear radiofrequency lesions in the atria designed to cure atrial fibrillation may impair atrial contractility. Reduced atrial function is partly due to loss of atrial myocardial mass, but regional delays in atrial activation and splinting of the atria by scarring also may contribute. |
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