A comparison of several methods used to quantify prepulse inhibition of eyeblink responding
Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reacti...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Blumenthal, Terry D. [verfasserIn] Elden, Aake [verfasserIn] Flaten, Magne Arve [verfasserIn] |
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E-Artikel |
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| Erschienen: |
Oxford, UK: Blackwell Publishing ; 2004 |
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| Umfang: |
Online-Ressource |
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2003 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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In: Psychophysiology - Malden, Mass. [u.a.] : Wiley-Blackwell, 1964, 41(2004), 2, Seite 0 |
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volume:41 ; year:2004 ; number:2 ; pages:0 |
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| DOI / URN: |
10.1111/j.1469-8986.2003.00144.x |
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| 520 | |a Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. | ||
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10.1111/j.1469-8986.2003.00144.x doi (DE-627)NLEJ243762321 DE-627 ger DE-627 rakwb Blumenthal, Terry D. verfasserin aut A comparison of several methods used to quantify prepulse inhibition of eyeblink responding Oxford, UK Blackwell Publishing 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| PPI Elden, Aake verfasserin aut Flaten, Magne Arve verfasserin aut In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 41(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:41 year:2004 number:2 pages:0 http://dx.doi.org/10.1111/j.1469-8986.2003.00144.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 41 2004 2 0 |
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10.1111/j.1469-8986.2003.00144.x doi (DE-627)NLEJ243762321 DE-627 ger DE-627 rakwb Blumenthal, Terry D. verfasserin aut A comparison of several methods used to quantify prepulse inhibition of eyeblink responding Oxford, UK Blackwell Publishing 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| PPI Elden, Aake verfasserin aut Flaten, Magne Arve verfasserin aut In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 41(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:41 year:2004 number:2 pages:0 http://dx.doi.org/10.1111/j.1469-8986.2003.00144.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 41 2004 2 0 |
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10.1111/j.1469-8986.2003.00144.x doi (DE-627)NLEJ243762321 DE-627 ger DE-627 rakwb Blumenthal, Terry D. verfasserin aut A comparison of several methods used to quantify prepulse inhibition of eyeblink responding Oxford, UK Blackwell Publishing 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| PPI Elden, Aake verfasserin aut Flaten, Magne Arve verfasserin aut In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 41(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:41 year:2004 number:2 pages:0 http://dx.doi.org/10.1111/j.1469-8986.2003.00144.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 41 2004 2 0 |
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10.1111/j.1469-8986.2003.00144.x doi (DE-627)NLEJ243762321 DE-627 ger DE-627 rakwb Blumenthal, Terry D. verfasserin aut A comparison of several methods used to quantify prepulse inhibition of eyeblink responding Oxford, UK Blackwell Publishing 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| PPI Elden, Aake verfasserin aut Flaten, Magne Arve verfasserin aut In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 41(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:41 year:2004 number:2 pages:0 http://dx.doi.org/10.1111/j.1469-8986.2003.00144.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 41 2004 2 0 |
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10.1111/j.1469-8986.2003.00144.x doi (DE-627)NLEJ243762321 DE-627 ger DE-627 rakwb Blumenthal, Terry D. verfasserin aut A comparison of several methods used to quantify prepulse inhibition of eyeblink responding Oxford, UK Blackwell Publishing 2004 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. 2003 Blackwell Publishing Journal Backfiles 1879-2005 |2003|||||||||| PPI Elden, Aake verfasserin aut Flaten, Magne Arve verfasserin aut In Psychophysiology Malden, Mass. [u.a.] : Wiley-Blackwell, 1964 41(2004), 2, Seite 0 Online-Ressource (DE-627)NLEJ243927487 (DE-600)1484299-3 1469-8986 nnns volume:41 year:2004 number:2 pages:0 http://dx.doi.org/10.1111/j.1469-8986.2003.00144.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 41 2004 2 0 |
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Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. |
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Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. |
| abstract_unstemmed |
Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. Proportion of difference was the method least affected by differences in control reactivity, and is the preferred method to use when quantifying PPI, both from a practical and a neurophysiological perspective. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ243762321</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707185403.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2004 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1111/j.1469-8986.2003.00144.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ243762321</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Blumenthal, Terry D.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">A comparison of several methods used to quantify prepulse inhibition of eyeblink responding</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford, UK</subfield><subfield code="b">Blackwell Publishing</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Several methods of quantifying prepulse inhibition (PPI) of eyeblink responding were compared in adult volunteers. Blink-eliciting stimuli were noise bursts at 85 or 100 dB, and prepulses were also noise bursts, at 55 or 70 dB and lead intervals of 60 or 120 ms. PPI was evaluated by comparing reactivity on prepulse and control trials within participants using the following methods: (1) difference between reactivity on prepulse and control trials; (2) reactivity on prepulse trials divided by that on control trials (proportion of control); (3) difference between reactivity on prepulse and control trials, divided by that on control trials (proportion of the difference from control); (4) range correction (maximum minus minimum reactivity, divided by the range of reactivity), across all control and prepulse trials; (5) z scores across all prepulse and control trials. Prepulses inhibited eyeblink response magnitude in all cases. 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