Cardiac failure in an infant with Chediak–Higashi syndrome: A hypothesis of the effect of diadenosine polyphosphates
A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A,...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ganschow, Rainer [verfasserIn] Grabhorn, Enke [verfasserIn] Lemke, Joachim [verfasserIn] |
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| Format: |
E-Artikel |
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| Erschienen: |
Copenhagen, Denmark: Munksgaard International Publishers ; 2002 |
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| Schlagwörter: |
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| Umfang: |
Online-Ressource |
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| Reproduktion: |
2008 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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| Übergeordnetes Werk: |
In: Pediatric allergy and immunology - Oxford [u.a.] : Wiley-Blackwell, 1990, 13(2002), 4, Seite 0 |
| Übergeordnetes Werk: |
volume:13 ; year:2002 ; number:4 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1034/j.1399-3038.2002.01052.x |
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| 520 | |a A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. | ||
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10.1034/j.1399-3038.2002.01052.x doi (DE-627)NLEJ243881398 DE-627 ger DE-627 rakwb Ganschow, Rainer verfasserin aut Cardiac failure in an infant with Chediak–Higashi syndrome: A hypothesis of the effect of diadenosine polyphosphates Copenhagen, Denmark Munksgaard International Publishers 2002 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| Chediak–Higashi syndrome Grabhorn, Enke verfasserin aut Lemke, Joachim verfasserin aut Lepler, Rudolf oth In Pediatric allergy and immunology Oxford [u.a.] : Wiley-Blackwell, 1990 13(2002), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926308 (DE-600)2008584-9 1399-3038 nnns volume:13 year:2002 number:4 pages:0 http://dx.doi.org/10.1034/j.1399-3038.2002.01052.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 13 2002 4 0 |
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10.1034/j.1399-3038.2002.01052.x doi (DE-627)NLEJ243881398 DE-627 ger DE-627 rakwb Ganschow, Rainer verfasserin aut Cardiac failure in an infant with Chediak–Higashi syndrome: A hypothesis of the effect of diadenosine polyphosphates Copenhagen, Denmark Munksgaard International Publishers 2002 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| Chediak–Higashi syndrome Grabhorn, Enke verfasserin aut Lemke, Joachim verfasserin aut Lepler, Rudolf oth In Pediatric allergy and immunology Oxford [u.a.] : Wiley-Blackwell, 1990 13(2002), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926308 (DE-600)2008584-9 1399-3038 nnns volume:13 year:2002 number:4 pages:0 http://dx.doi.org/10.1034/j.1399-3038.2002.01052.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 13 2002 4 0 |
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10.1034/j.1399-3038.2002.01052.x doi (DE-627)NLEJ243881398 DE-627 ger DE-627 rakwb Ganschow, Rainer verfasserin aut Cardiac failure in an infant with Chediak–Higashi syndrome: A hypothesis of the effect of diadenosine polyphosphates Copenhagen, Denmark Munksgaard International Publishers 2002 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| Chediak–Higashi syndrome Grabhorn, Enke verfasserin aut Lemke, Joachim verfasserin aut Lepler, Rudolf oth In Pediatric allergy and immunology Oxford [u.a.] : Wiley-Blackwell, 1990 13(2002), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926308 (DE-600)2008584-9 1399-3038 nnns volume:13 year:2002 number:4 pages:0 http://dx.doi.org/10.1034/j.1399-3038.2002.01052.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 13 2002 4 0 |
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10.1034/j.1399-3038.2002.01052.x doi (DE-627)NLEJ243881398 DE-627 ger DE-627 rakwb Ganschow, Rainer verfasserin aut Cardiac failure in an infant with Chediak–Higashi syndrome: A hypothesis of the effect of diadenosine polyphosphates Copenhagen, Denmark Munksgaard International Publishers 2002 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| Chediak–Higashi syndrome Grabhorn, Enke verfasserin aut Lemke, Joachim verfasserin aut Lepler, Rudolf oth In Pediatric allergy and immunology Oxford [u.a.] : Wiley-Blackwell, 1990 13(2002), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926308 (DE-600)2008584-9 1399-3038 nnns volume:13 year:2002 number:4 pages:0 http://dx.doi.org/10.1034/j.1399-3038.2002.01052.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 13 2002 4 0 |
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10.1034/j.1399-3038.2002.01052.x doi (DE-627)NLEJ243881398 DE-627 ger DE-627 rakwb Ganschow, Rainer verfasserin aut Cardiac failure in an infant with Chediak–Higashi syndrome: A hypothesis of the effect of diadenosine polyphosphates Copenhagen, Denmark Munksgaard International Publishers 2002 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. 2008 Blackwell Publishing Journal Backfiles 1879-2005 |2008|||||||||| Chediak–Higashi syndrome Grabhorn, Enke verfasserin aut Lemke, Joachim verfasserin aut Lepler, Rudolf oth In Pediatric allergy and immunology Oxford [u.a.] : Wiley-Blackwell, 1990 13(2002), 4, Seite 0 Online-Ressource (DE-627)NLEJ243926308 (DE-600)2008584-9 1399-3038 nnns volume:13 year:2002 number:4 pages:0 http://dx.doi.org/10.1034/j.1399-3038.2002.01052.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 13 2002 4 0 |
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A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. |
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A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. |
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A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ243881398</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20210707190927.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">120427s2002 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1034/j.1399-3038.2002.01052.x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ243881398</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ganschow, Rainer</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Cardiac failure in an infant with Chediak–Higashi syndrome: A hypothesis of the effect of diadenosine polyphosphates</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Copenhagen, Denmark</subfield><subfield code="b">Munksgaard International Publishers</subfield><subfield code="c">2002</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">A 14-week-old boy with undiagnosed Chediak–Higashi syndrome developed fever with a high temperature and acute cardiac failure after having received a scheduled vaccination. We hypothesize that decreased concentrations and receptor binding of serum and tissue diadenosine polyphosphates, such as AP4A, AP5A, or AP6A, which are stored in various tissues and serve as extra-cellular signaling molecules or are secreted by cells in response to physiologically stressful stimuli, lead to the observed severe tachyarrhythmia. Diadenosine polyphosphates normally have a negative chronotropic and inotropic effect. This is the first report of severe cardiac failure in a child with Chediak–Higashi syndrome and we suggest that cardiac arrhythmias should be considered in such children in the event of high fever. Our hypothesis requires further investigation in other patients.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="d">2008</subfield><subfield code="f">Blackwell Publishing Journal Backfiles 1879-2005</subfield><subfield code="7">|2008||||||||||</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chediak–Higashi syndrome</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Grabhorn, Enke</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lemke, Joachim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lepler, Rudolf</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Pediatric allergy and immunology</subfield><subfield code="d">Oxford [u.a.] : Wiley-Blackwell, 1990</subfield><subfield code="g">13(2002), 4, Seite 0</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)NLEJ243926308</subfield><subfield code="w">(DE-600)2008584-9</subfield><subfield code="x">1399-3038</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:13</subfield><subfield code="g">year:2002</subfield><subfield code="g">number:4</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://dx.doi.org/10.1034/j.1399-3038.2002.01052.x</subfield><subfield code="q">text/html</subfield><subfield code="x">Verlag</subfield><subfield code="z">Deutschlandweit zugänglich</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DJB</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">13</subfield><subfield code="j">2002</subfield><subfield code="e">4</subfield><subfield code="h">0</subfield></datafield></record></collection>
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