QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy
This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients wi...
Ausführliche Beschreibung
Autor*in: |
MEZILIS, NICK E. [verfasserIn] PARTHENAKIS, FRAGISKOS I. [verfasserIn] KANAKARAKI, MARINA K. [verfasserIn] |
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E-Artikel |
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Erschienen: |
Oxford, UK: Blackwell Publishing Ltd ; 1998 |
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Umfang: |
Online-Ressource |
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Reproduktion: |
2006 ; Blackwell Publishing Journal Backfiles 1879-2005 |
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Übergeordnetes Werk: |
In: Pacing and clinical electrophysiology - New York, NY [u.a.] : Wiley-Blackwell, 1978, 21(1998), 11, Seite 0 |
Übergeordnetes Werk: |
volume:21 ; year:1998 ; number:11 ; pages:0 |
Links: |
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DOI / URN: |
10.1111/j.1540-8159.1998.tb01187.x |
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520 | |a This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. | ||
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10.1111/j.1540-8159.1998.tb01187.x doi (DE-627)NLEJ243919239 DE-627 ger DE-627 rakwb MEZILIS, NICK E. verfasserin aut QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| hypertrophic cardiomyopathy PARTHENAKIS, FRAGISKOS I. verfasserin aut KANAKARAKI, MARINA K. verfasserin aut KANOUPAKIS, EMMANOUEL M. oth VARDAS, PANOS E. oth In Pacing and clinical electrophysiology New York, NY [u.a.] : Wiley-Blackwell, 1978 21(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243926928 (DE-600)2037547-5 1540-8159 nnns volume:21 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1540-8159.1998.tb01187.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 21 1998 11 0 |
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10.1111/j.1540-8159.1998.tb01187.x doi (DE-627)NLEJ243919239 DE-627 ger DE-627 rakwb MEZILIS, NICK E. verfasserin aut QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| hypertrophic cardiomyopathy PARTHENAKIS, FRAGISKOS I. verfasserin aut KANAKARAKI, MARINA K. verfasserin aut KANOUPAKIS, EMMANOUEL M. oth VARDAS, PANOS E. oth In Pacing and clinical electrophysiology New York, NY [u.a.] : Wiley-Blackwell, 1978 21(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243926928 (DE-600)2037547-5 1540-8159 nnns volume:21 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1540-8159.1998.tb01187.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 21 1998 11 0 |
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10.1111/j.1540-8159.1998.tb01187.x doi (DE-627)NLEJ243919239 DE-627 ger DE-627 rakwb MEZILIS, NICK E. verfasserin aut QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| hypertrophic cardiomyopathy PARTHENAKIS, FRAGISKOS I. verfasserin aut KANAKARAKI, MARINA K. verfasserin aut KANOUPAKIS, EMMANOUEL M. oth VARDAS, PANOS E. oth In Pacing and clinical electrophysiology New York, NY [u.a.] : Wiley-Blackwell, 1978 21(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243926928 (DE-600)2037547-5 1540-8159 nnns volume:21 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1540-8159.1998.tb01187.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 21 1998 11 0 |
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10.1111/j.1540-8159.1998.tb01187.x doi (DE-627)NLEJ243919239 DE-627 ger DE-627 rakwb MEZILIS, NICK E. verfasserin aut QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| hypertrophic cardiomyopathy PARTHENAKIS, FRAGISKOS I. verfasserin aut KANAKARAKI, MARINA K. verfasserin aut KANOUPAKIS, EMMANOUEL M. oth VARDAS, PANOS E. oth In Pacing and clinical electrophysiology New York, NY [u.a.] : Wiley-Blackwell, 1978 21(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243926928 (DE-600)2037547-5 1540-8159 nnns volume:21 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1540-8159.1998.tb01187.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 21 1998 11 0 |
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10.1111/j.1540-8159.1998.tb01187.x doi (DE-627)NLEJ243919239 DE-627 ger DE-627 rakwb MEZILIS, NICK E. verfasserin aut QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy Oxford, UK Blackwell Publishing Ltd 1998 Online-Ressource nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. 2006 Blackwell Publishing Journal Backfiles 1879-2005 |2006|||||||||| hypertrophic cardiomyopathy PARTHENAKIS, FRAGISKOS I. verfasserin aut KANAKARAKI, MARINA K. verfasserin aut KANOUPAKIS, EMMANOUEL M. oth VARDAS, PANOS E. oth In Pacing and clinical electrophysiology New York, NY [u.a.] : Wiley-Blackwell, 1978 21(1998), 11, Seite 0 Online-Ressource (DE-627)NLEJ243926928 (DE-600)2037547-5 1540-8159 nnns volume:21 year:1998 number:11 pages:0 http://dx.doi.org/10.1111/j.1540-8159.1998.tb01187.x text/html Verlag Deutschlandweit zugänglich Volltext GBV_USEFLAG_U ZDB-1-DJB GBV_NL_ARTICLE AR 21 1998 11 0 |
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qt variability before and after episodes of nonsustained ventricular tachycardia in patients with hypertrophic cardiomyopathy |
title_auth |
QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy |
abstract |
This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. |
abstractGer |
This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. |
abstract_unstemmed |
This study examined the changes in QT dynamics occurring during 5-minute intervals sampled immediately before and 1 hour after episodes of nonsustained ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM). Twenty-four hour Holter recordings were performed in 10 patients with HCM in the absence of antiarrhythmic medications and processed by the ELA Medical QT analysis software. All sinus complexes were averaged over 30-second segments and 2,880 templates were created. For each template, a mean corrected QTec (time interval between the onset of QRS and the end of the T wave) and QTac (time interval between the onset of the QRS and the peak of the T wave) were calculated, with their standard deviations (SDQTe and SDQTa) taken as indices of QT variability. The slopes of the regression line for the QTe and QTa against the corresponding RR also were calculated. Forty 5-minute segments were analyzed immediately before (sample A) and 1 hour after (sample B) 20 episodes of nonsustained VT. QTac was significantly longer in group A than in group R (321 ± 20 vs 312 ± 22, P < 0.0001) and SDQTa was significantly lower (2.8 ± 1.2 vs 4.7 ± 3.7, P < 0.03). There were no significant differences in QTec, SDQTe, QTe/RR and QTa/RR before and after the episodes. Our data indicate that in patients with HCM, the averaged QTac is significantly longer and the QTa variability significantly lower before episodes of nonsustained VT. |
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11 |
title_short |
QT Variability Before and After Episodes of Nonsustained Ventricular Tachycardia in Patients with Hypertrophic Cardiomyopathy |
url |
http://dx.doi.org/10.1111/j.1540-8159.1998.tb01187.x |
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author2 |
PARTHENAKIS, FRAGISKOS I. KANAKARAKI, MARINA K. KANOUPAKIS, EMMANOUEL M. VARDAS, PANOS E. |
author2Str |
PARTHENAKIS, FRAGISKOS I. KANAKARAKI, MARINA K. KANOUPAKIS, EMMANOUEL M. VARDAS, PANOS E. |
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NLEJ243926928 |
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doi_str |
10.1111/j.1540-8159.1998.tb01187.x |
up_date |
2024-07-06T06:56:56.505Z |
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7.400016 |