Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265
Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate inte...
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E-Artikel |
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Walter de Gruyter ; 2010 |
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Walter de Gruyter Online Zeitschriften |
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Enthalten in: Clinical chemistry and laboratory medicine - Berlin [u.a.] : De Gruyter, 1998, 48(2010), 10 vom: 7. Juli, Seite 1455-1461 |
| Übergeordnetes Werk: |
volume:48 ; year:2010 ; number:10 ; day:7 ; month:07 ; pages:1455-1461 ; extent:7 |
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| DOI / URN: |
10.1515/CCLM.2010.279 |
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NLEJ246731559 |
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| 520 | |a Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. | ||
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10.1515/CCLM.2010.279 doi artikel_Grundlieferung.pp (DE-627)NLEJ246731559 DE-627 ger DE-627 rakwb Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 Walter de Gruyter 2010 7 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. Walter de Gruyter Online Zeitschriften bilirubin measurement transcutaneous bilirubinometer neonatal jaundice oximetry point-of-care testing Mielsch, Caroline oth Zimmermann, Andrea oth Wagner, Dieter oth Matthes, Bianca oth Schlebusch, Harald oth Luppa, Peter B. oth Enthalten in Clinical chemistry and laboratory medicine Berlin [u.a.] : De Gruyter, 1998 48(2010), 10 vom: 7. Juli, Seite 1455-1461 (DE-627)NLEJ248235222 (DE-600)1492732-9 1437-4331 nnns volume:48 year:2010 number:10 day:7 month:07 pages:1455-1461 extent:7 https://doi.org/10.1515/CCLM.2010.279 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 48 2010 10 7 07 1455-1461 7 |
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10.1515/CCLM.2010.279 doi artikel_Grundlieferung.pp (DE-627)NLEJ246731559 DE-627 ger DE-627 rakwb Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 Walter de Gruyter 2010 7 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. Walter de Gruyter Online Zeitschriften bilirubin measurement transcutaneous bilirubinometer neonatal jaundice oximetry point-of-care testing Mielsch, Caroline oth Zimmermann, Andrea oth Wagner, Dieter oth Matthes, Bianca oth Schlebusch, Harald oth Luppa, Peter B. oth Enthalten in Clinical chemistry and laboratory medicine Berlin [u.a.] : De Gruyter, 1998 48(2010), 10 vom: 7. Juli, Seite 1455-1461 (DE-627)NLEJ248235222 (DE-600)1492732-9 1437-4331 nnns volume:48 year:2010 number:10 day:7 month:07 pages:1455-1461 extent:7 https://doi.org/10.1515/CCLM.2010.279 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 48 2010 10 7 07 1455-1461 7 |
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10.1515/CCLM.2010.279 doi artikel_Grundlieferung.pp (DE-627)NLEJ246731559 DE-627 ger DE-627 rakwb Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 Walter de Gruyter 2010 7 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. Walter de Gruyter Online Zeitschriften bilirubin measurement transcutaneous bilirubinometer neonatal jaundice oximetry point-of-care testing Mielsch, Caroline oth Zimmermann, Andrea oth Wagner, Dieter oth Matthes, Bianca oth Schlebusch, Harald oth Luppa, Peter B. oth Enthalten in Clinical chemistry and laboratory medicine Berlin [u.a.] : De Gruyter, 1998 48(2010), 10 vom: 7. Juli, Seite 1455-1461 (DE-627)NLEJ248235222 (DE-600)1492732-9 1437-4331 nnns volume:48 year:2010 number:10 day:7 month:07 pages:1455-1461 extent:7 https://doi.org/10.1515/CCLM.2010.279 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 48 2010 10 7 07 1455-1461 7 |
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10.1515/CCLM.2010.279 doi artikel_Grundlieferung.pp (DE-627)NLEJ246731559 DE-627 ger DE-627 rakwb Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 Walter de Gruyter 2010 7 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. Walter de Gruyter Online Zeitschriften bilirubin measurement transcutaneous bilirubinometer neonatal jaundice oximetry point-of-care testing Mielsch, Caroline oth Zimmermann, Andrea oth Wagner, Dieter oth Matthes, Bianca oth Schlebusch, Harald oth Luppa, Peter B. oth Enthalten in Clinical chemistry and laboratory medicine Berlin [u.a.] : De Gruyter, 1998 48(2010), 10 vom: 7. Juli, Seite 1455-1461 (DE-627)NLEJ248235222 (DE-600)1492732-9 1437-4331 nnns volume:48 year:2010 number:10 day:7 month:07 pages:1455-1461 extent:7 https://doi.org/10.1515/CCLM.2010.279 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 48 2010 10 7 07 1455-1461 7 |
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10.1515/CCLM.2010.279 doi artikel_Grundlieferung.pp (DE-627)NLEJ246731559 DE-627 ger DE-627 rakwb Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 Walter de Gruyter 2010 7 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. Walter de Gruyter Online Zeitschriften bilirubin measurement transcutaneous bilirubinometer neonatal jaundice oximetry point-of-care testing Mielsch, Caroline oth Zimmermann, Andrea oth Wagner, Dieter oth Matthes, Bianca oth Schlebusch, Harald oth Luppa, Peter B. oth Enthalten in Clinical chemistry and laboratory medicine Berlin [u.a.] : De Gruyter, 1998 48(2010), 10 vom: 7. Juli, Seite 1455-1461 (DE-627)NLEJ248235222 (DE-600)1492732-9 1437-4331 nnns volume:48 year:2010 number:10 day:7 month:07 pages:1455-1461 extent:7 https://doi.org/10.1515/CCLM.2010.279 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 48 2010 10 7 07 1455-1461 7 |
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Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 |
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Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 |
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10.1515/CCLM.2010.279 |
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point-of-care determination of neonatal bilirubin with the blood gas analyzer rapidlab 1265 |
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Point-of-care determination of neonatal bilirubin with the blood gas analyzer RapidLab 1265 |
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Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. |
| abstractGer |
Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. |
| abstract_unstemmed |
Background: The aim of the study was to evaluate the comparability of the new neonatal bilirubin method on the RapidLab 1265 blood gas analyzer. This point-of-care testing (POCT) device has the option for the determination of neonatal bilirubin, making it potentially valuable for use in neonate intensive care units or in outpatient ambulances. Methods: We paired 240 patient samples for intermethod comparisons between the new POCT method and the routine laboratory method (Vitros 350 chemistry system with BuBc slide). In parallel, a transcutaneous jaundice meter (JM-103) was applied to the newborns. Low birthweight and premature neonates were excluded from the trial. The turn-around-time (TAT) for the POCT method was also compared with the routine method, and the practicality of the new analyzer was evaluated for clinical purposes. Results: Bilirubin measurements using the RapidLab 1265 are suitable for the application in newborns. For imprecision, coefficients of variation between 5.6% and 23% were found. The correlation between the Vitros 350 (x) and RapidLab 1265 (y) was y=1.0x–0.1 (r=0.91), with a mean bias of +0.1 mg/dL and a 95% limit of agreement of ±2.5 mg/dL. As in all POCT methods, the TAT was significantly lower than that of the core laboratory. Conclusions: In contrast to the JM-103, the results of the RapidLab 1265 correlated closely with the Vitros 350, although occasional results of both methods were more different than expected. In general, the RapidLab 1265 blood gas analyzer provides clinically useful bilirubin results using neonatal whole blood samples, although imprecision data are higher than for the laboratory method. The POCT device is suitable for neonatal intensive care units after thoroughly training the employees that will use the device. Clin Chem Lab Med 2010;48:1455–61. |
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Mielsch, Caroline Zimmermann, Andrea Wagner, Dieter Matthes, Bianca Schlebusch, Harald Luppa, Peter B. |
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