Risk factors for fetal-to-maternal transfusion in Rh D-negative women – results of a prospective study on 942 pregnant women
Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal t...
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Walter de Gruyter ; 2005 |
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Copyright © 2004 by Walter de Gruyter GmbH & Co. KG |
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In: 32(2005), 3 vom: 01. Juni, Seite 254-257 volume:32 ; year:2005 ; number:3 ; day:01 ; month:06 ; pages:254-257 ; extent:4 |
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10.1515/JPM.2004.047 |
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| 520 | |a Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. | ||
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| 700 | 1 | |a Dudenhausen, J.W. |4 oth | |
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10.1515/JPM.2004.047 doi artikel_Grundlieferung.pp (DE-627)NLEJ247138835 DE-627 ger DE-627 rakwb Risk factors for fetal-to-maternal transfusion in Rh D-negative women – results of a prospective study on 942 pregnant women Walter de Gruyter 2005 4 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Walter de Gruyter Online Zeitschriften David, M. oth Smidt, J. oth Chen, F.C.K. oth Stein, U. oth Dudenhausen, J.W. oth In 32(2005), 3 vom: 01. Juni, Seite 254-257 volume:32 year:2005 number:3 day:01 month:06 pages:254-257 extent:4 https://doi.org/10.1515/JPM.2004.047 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 32 2005 3 01 06 254-257 4 |
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10.1515/JPM.2004.047 doi artikel_Grundlieferung.pp (DE-627)NLEJ247138835 DE-627 ger DE-627 rakwb Risk factors for fetal-to-maternal transfusion in Rh D-negative women – results of a prospective study on 942 pregnant women Walter de Gruyter 2005 4 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Walter de Gruyter Online Zeitschriften David, M. oth Smidt, J. oth Chen, F.C.K. oth Stein, U. oth Dudenhausen, J.W. oth In 32(2005), 3 vom: 01. Juni, Seite 254-257 volume:32 year:2005 number:3 day:01 month:06 pages:254-257 extent:4 https://doi.org/10.1515/JPM.2004.047 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 32 2005 3 01 06 254-257 4 |
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10.1515/JPM.2004.047 doi artikel_Grundlieferung.pp (DE-627)NLEJ247138835 DE-627 ger DE-627 rakwb Risk factors for fetal-to-maternal transfusion in Rh D-negative women – results of a prospective study on 942 pregnant women Walter de Gruyter 2005 4 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Walter de Gruyter Online Zeitschriften David, M. oth Smidt, J. oth Chen, F.C.K. oth Stein, U. oth Dudenhausen, J.W. oth In 32(2005), 3 vom: 01. Juni, Seite 254-257 volume:32 year:2005 number:3 day:01 month:06 pages:254-257 extent:4 https://doi.org/10.1515/JPM.2004.047 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 32 2005 3 01 06 254-257 4 |
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10.1515/JPM.2004.047 doi artikel_Grundlieferung.pp (DE-627)NLEJ247138835 DE-627 ger DE-627 rakwb Risk factors for fetal-to-maternal transfusion in Rh D-negative women – results of a prospective study on 942 pregnant women Walter de Gruyter 2005 4 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Walter de Gruyter Online Zeitschriften David, M. oth Smidt, J. oth Chen, F.C.K. oth Stein, U. oth Dudenhausen, J.W. oth In 32(2005), 3 vom: 01. Juni, Seite 254-257 volume:32 year:2005 number:3 day:01 month:06 pages:254-257 extent:4 https://doi.org/10.1515/JPM.2004.047 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 32 2005 3 01 06 254-257 4 |
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10.1515/JPM.2004.047 doi artikel_Grundlieferung.pp (DE-627)NLEJ247138835 DE-627 ger DE-627 rakwb Risk factors for fetal-to-maternal transfusion in Rh D-negative women – results of a prospective study on 942 pregnant women Walter de Gruyter 2005 4 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Copyright © 2004 by Walter de Gruyter GmbH & Co. KG Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Walter de Gruyter Online Zeitschriften David, M. oth Smidt, J. oth Chen, F.C.K. oth Stein, U. oth Dudenhausen, J.W. oth In 32(2005), 3 vom: 01. Juni, Seite 254-257 volume:32 year:2005 number:3 day:01 month:06 pages:254-257 extent:4 https://doi.org/10.1515/JPM.2004.047 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 32 2005 3 01 06 254-257 4 |
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Risk factors for fetal-to-maternal transfusion in Rh D-negative women – results of a prospective study on 942 pregnant women |
| abstract |
Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Copyright © 2004 by Walter de Gruyter GmbH & Co. KG |
| abstractGer |
Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Copyright © 2004 by Walter de Gruyter GmbH & Co. KG |
| abstract_unstemmed |
Aims: To investigate the incidence of severe fetal-to-maternaltransfusion after delivery and to identify riskfactors. Material and methods: In a prospective study at theDepartment of Obstetrics, Charité, Campus Virchow-Klinikum, Berlin, Germany, we analyzed the incidence ofsevere fetal-to-maternal transfusion (>10 ml) and fetalto-maternal hemorrhage (>25 ml) in Rh D-negative pregnantwomen after delivery of Rh D-positive infants. 942women were included in the study and Kleihauer-Betketests were performed. The results were compared toperinatal data. Results: Fetal-to-maternal hemorrhage occurred in 13cases out of 942 (incidence of 1.3%) and severe fetalto-maternal transfusion in 61 cases (6.5%). In all of thecases with fetal-to-maternal hemorrhage, mothers werecompatible with their infants in ABO-system. The incidenceof fetal-to-maternal transfusion and its severeform was significantly higher in twin pregnancies (7/21cases and 5/21 cases respectively, 33.3% and 23.8%)than in singleton pregnancies (22.5% and 5.9%,P<0.001). All other factors, such as maternal age, parity,ethnicity, mode of delivery, presentation, duration of firstand second stage of labor, CTG, or Apgar score were notassociated with an increased risk of severe fetal-tomaternal transfusion. Conclusions: Twin pregnancy is the only independentrisk factor for severe fetal-to-maternal transfusion. ABO-incompatibilitybetween mother and infant seems to beprotective against Rh D-alloimmunization. Copyright © 2004 by Walter de Gruyter GmbH & Co. KG |
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