Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition
Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by...
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E-Artikel |
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| Erschienen: |
Walter de Gruyter ; 2008 2008 |
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| Schlagwörter: |
Microbial invasion of the amniotic cavity (MIAC) pre-B cell colony-enhancing factor (PBEF) |
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| Anmerkung: |
©2008 by Walter de Gruyter Berlin New York |
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| Umfang: |
12 |
| Reproduktion: |
Walter de Gruyter Online Zeitschriften |
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| Übergeordnetes Werk: |
Enthalten in: Journal of perinatal medicine - Berlin [u.a.] : de Gruyter, 1973, 36(2008 2008), 6 vom: 04 04., Seite 485-496 |
| Übergeordnetes Werk: |
volume:36 ; year:2008 2008 ; number:6 ; day:04 04 ; month:07 ; pages:485-496 ; extent:12 |
| Links: |
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| DOI / URN: |
10.1515/JPM.2008.084 |
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| Katalog-ID: |
NLEJ247143537 |
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| 245 | 1 | 0 | |a Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition |
| 264 | 1 | |b Walter de Gruyter |c 2008 2008 | |
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| 500 | |a ©2008 by Walter de Gruyter Berlin New York | ||
| 520 | |a Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. | ||
| 533 | |f Walter de Gruyter Online Zeitschriften | ||
| 650 | 4 | |a Microbial invasion of the amniotic cavity (MIAC) | |
| 650 | 4 | |a pre-B cell colony-enhancing factor (PBEF) | |
| 650 | 4 | |a preterm labor | |
| 650 | 4 | |a preterm prelabor rupture of membranes (preterm PROM) | |
| 650 | 4 | |a visfatin | |
| 700 | 1 | |a Mazaki-Tovi, Shali |4 oth | |
| 700 | 1 | |a Romero, Roberto |4 oth | |
| 700 | 1 | |a Kusanovic, Juan Pedro |4 oth | |
| 700 | 1 | |a Erez, Offer |4 oth | |
| 700 | 1 | |a Gotsch, Francesca |4 oth | |
| 700 | 1 | |a Mittal, Pooja |4 oth | |
| 700 | 1 | |a Than, Nandor Gabor |4 oth | |
| 700 | 1 | |a Nhan-Chang, Chia-Lang |4 oth | |
| 700 | 1 | |a Hamill, Neil |4 oth | |
| 700 | 1 | |a Vaisbuch, Edi |4 oth | |
| 700 | 1 | |a Chaiworapongsa, Tinnakorn |4 oth | |
| 700 | 1 | |a Edwin, Samuel S. |4 oth | |
| 700 | 1 | |a Nien, Jyh Kae |4 oth | |
| 700 | 1 | |a Gomez, Ricardo |4 oth | |
| 700 | 1 | |a Espinoza, Jimmy |4 oth | |
| 700 | 1 | |a Kendal-Wright, Claire |4 oth | |
| 700 | 1 | |a Hassan, Sonia S. |4 oth | |
| 700 | 1 | |a Bryant-Greenwood, Gillian |4 oth | |
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10.1515/JPM.2008.084 doi artikel_Grundlieferung.pp (DE-627)NLEJ247143537 DE-627 ger DE-627 rakwb Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition Walter de Gruyter 2008 2008 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ©2008 by Walter de Gruyter Berlin New York Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. Walter de Gruyter Online Zeitschriften Microbial invasion of the amniotic cavity (MIAC) pre-B cell colony-enhancing factor (PBEF) preterm labor preterm prelabor rupture of membranes (preterm PROM) visfatin Mazaki-Tovi, Shali oth Romero, Roberto oth Kusanovic, Juan Pedro oth Erez, Offer oth Gotsch, Francesca oth Mittal, Pooja oth Than, Nandor Gabor oth Nhan-Chang, Chia-Lang oth Hamill, Neil oth Vaisbuch, Edi oth Chaiworapongsa, Tinnakorn oth Edwin, Samuel S. oth Nien, Jyh Kae oth Gomez, Ricardo oth Espinoza, Jimmy oth Kendal-Wright, Claire oth Hassan, Sonia S. oth Bryant-Greenwood, Gillian oth Enthalten in Journal of perinatal medicine Berlin [u.a.] : de Gruyter, 1973 36(2008 2008), 6 vom: 04 04., Seite 485-496 (DE-627)NLEJ248236229 (DE-600)1467968-1 16193997 nnns volume:36 year:2008 2008 number:6 day:04 04 month:07 pages:485-496 extent:12 https://doi.org/10.1515/JPM.2008.084 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 36 2008 2008 6 04 04 07 07 485-496 12 |
| spelling |
10.1515/JPM.2008.084 doi artikel_Grundlieferung.pp (DE-627)NLEJ247143537 DE-627 ger DE-627 rakwb Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition Walter de Gruyter 2008 2008 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ©2008 by Walter de Gruyter Berlin New York Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. Walter de Gruyter Online Zeitschriften Microbial invasion of the amniotic cavity (MIAC) pre-B cell colony-enhancing factor (PBEF) preterm labor preterm prelabor rupture of membranes (preterm PROM) visfatin Mazaki-Tovi, Shali oth Romero, Roberto oth Kusanovic, Juan Pedro oth Erez, Offer oth Gotsch, Francesca oth Mittal, Pooja oth Than, Nandor Gabor oth Nhan-Chang, Chia-Lang oth Hamill, Neil oth Vaisbuch, Edi oth Chaiworapongsa, Tinnakorn oth Edwin, Samuel S. oth Nien, Jyh Kae oth Gomez, Ricardo oth Espinoza, Jimmy oth Kendal-Wright, Claire oth Hassan, Sonia S. oth Bryant-Greenwood, Gillian oth Enthalten in Journal of perinatal medicine Berlin [u.a.] : de Gruyter, 1973 36(2008 2008), 6 vom: 04 04., Seite 485-496 (DE-627)NLEJ248236229 (DE-600)1467968-1 16193997 nnns volume:36 year:2008 2008 number:6 day:04 04 month:07 pages:485-496 extent:12 https://doi.org/10.1515/JPM.2008.084 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 36 2008 2008 6 04 04 07 07 485-496 12 |
| allfields_unstemmed |
10.1515/JPM.2008.084 doi artikel_Grundlieferung.pp (DE-627)NLEJ247143537 DE-627 ger DE-627 rakwb Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition Walter de Gruyter 2008 2008 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ©2008 by Walter de Gruyter Berlin New York Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. Walter de Gruyter Online Zeitschriften Microbial invasion of the amniotic cavity (MIAC) pre-B cell colony-enhancing factor (PBEF) preterm labor preterm prelabor rupture of membranes (preterm PROM) visfatin Mazaki-Tovi, Shali oth Romero, Roberto oth Kusanovic, Juan Pedro oth Erez, Offer oth Gotsch, Francesca oth Mittal, Pooja oth Than, Nandor Gabor oth Nhan-Chang, Chia-Lang oth Hamill, Neil oth Vaisbuch, Edi oth Chaiworapongsa, Tinnakorn oth Edwin, Samuel S. oth Nien, Jyh Kae oth Gomez, Ricardo oth Espinoza, Jimmy oth Kendal-Wright, Claire oth Hassan, Sonia S. oth Bryant-Greenwood, Gillian oth Enthalten in Journal of perinatal medicine Berlin [u.a.] : de Gruyter, 1973 36(2008 2008), 6 vom: 04 04., Seite 485-496 (DE-627)NLEJ248236229 (DE-600)1467968-1 16193997 nnns volume:36 year:2008 2008 number:6 day:04 04 month:07 pages:485-496 extent:12 https://doi.org/10.1515/JPM.2008.084 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 36 2008 2008 6 04 04 07 07 485-496 12 |
| allfieldsGer |
10.1515/JPM.2008.084 doi artikel_Grundlieferung.pp (DE-627)NLEJ247143537 DE-627 ger DE-627 rakwb Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition Walter de Gruyter 2008 2008 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ©2008 by Walter de Gruyter Berlin New York Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. Walter de Gruyter Online Zeitschriften Microbial invasion of the amniotic cavity (MIAC) pre-B cell colony-enhancing factor (PBEF) preterm labor preterm prelabor rupture of membranes (preterm PROM) visfatin Mazaki-Tovi, Shali oth Romero, Roberto oth Kusanovic, Juan Pedro oth Erez, Offer oth Gotsch, Francesca oth Mittal, Pooja oth Than, Nandor Gabor oth Nhan-Chang, Chia-Lang oth Hamill, Neil oth Vaisbuch, Edi oth Chaiworapongsa, Tinnakorn oth Edwin, Samuel S. oth Nien, Jyh Kae oth Gomez, Ricardo oth Espinoza, Jimmy oth Kendal-Wright, Claire oth Hassan, Sonia S. oth Bryant-Greenwood, Gillian oth Enthalten in Journal of perinatal medicine Berlin [u.a.] : de Gruyter, 1973 36(2008 2008), 6 vom: 04 04., Seite 485-496 (DE-627)NLEJ248236229 (DE-600)1467968-1 16193997 nnns volume:36 year:2008 2008 number:6 day:04 04 month:07 pages:485-496 extent:12 https://doi.org/10.1515/JPM.2008.084 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 36 2008 2008 6 04 04 07 07 485-496 12 |
| allfieldsSound |
10.1515/JPM.2008.084 doi artikel_Grundlieferung.pp (DE-627)NLEJ247143537 DE-627 ger DE-627 rakwb Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition Walter de Gruyter 2008 2008 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ©2008 by Walter de Gruyter Berlin New York Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. Walter de Gruyter Online Zeitschriften Microbial invasion of the amniotic cavity (MIAC) pre-B cell colony-enhancing factor (PBEF) preterm labor preterm prelabor rupture of membranes (preterm PROM) visfatin Mazaki-Tovi, Shali oth Romero, Roberto oth Kusanovic, Juan Pedro oth Erez, Offer oth Gotsch, Francesca oth Mittal, Pooja oth Than, Nandor Gabor oth Nhan-Chang, Chia-Lang oth Hamill, Neil oth Vaisbuch, Edi oth Chaiworapongsa, Tinnakorn oth Edwin, Samuel S. oth Nien, Jyh Kae oth Gomez, Ricardo oth Espinoza, Jimmy oth Kendal-Wright, Claire oth Hassan, Sonia S. oth Bryant-Greenwood, Gillian oth Enthalten in Journal of perinatal medicine Berlin [u.a.] : de Gruyter, 1973 36(2008 2008), 6 vom: 04 04., Seite 485-496 (DE-627)NLEJ248236229 (DE-600)1467968-1 16193997 nnns volume:36 year:2008 2008 number:6 day:04 04 month:07 pages:485-496 extent:12 https://doi.org/10.1515/JPM.2008.084 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 36 2008 2008 6 04 04 07 07 485-496 12 |
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Mazaki-Tovi, Shali @@oth@@ Romero, Roberto @@oth@@ Kusanovic, Juan Pedro @@oth@@ Erez, Offer @@oth@@ Gotsch, Francesca @@oth@@ Mittal, Pooja @@oth@@ Than, Nandor Gabor @@oth@@ Nhan-Chang, Chia-Lang @@oth@@ Hamill, Neil @@oth@@ Vaisbuch, Edi @@oth@@ Chaiworapongsa, Tinnakorn @@oth@@ Edwin, Samuel S. @@oth@@ Nien, Jyh Kae @@oth@@ Gomez, Ricardo @@oth@@ Espinoza, Jimmy @@oth@@ Kendal-Wright, Claire @@oth@@ Hassan, Sonia S. @@oth@@ Bryant-Greenwood, Gillian @@oth@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ247143537</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506082210.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220814s2008 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1515/JPM.2008.084</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">artikel_Grundlieferung.pp</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ247143537</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="b">Walter de Gruyter</subfield><subfield code="c">2008 2008</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">©2008 by Walter de Gruyter Berlin New York</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Walter de Gruyter Online Zeitschriften</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbial invasion of the amniotic cavity (MIAC)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">pre-B cell colony-enhancing factor (PBEF)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">preterm labor</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">preterm prelabor rupture of membranes (preterm PROM)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield 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Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition Microbial invasion of the amniotic cavity (MIAC) pre-B cell colony-enhancing factor (PBEF) preterm labor preterm prelabor rupture of membranes (preterm PROM) visfatin |
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misc Microbial invasion of the amniotic cavity (MIAC) misc pre-B cell colony-enhancing factor (PBEF) misc preterm labor misc preterm prelabor rupture of membranes (preterm PROM) misc visfatin |
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misc Microbial invasion of the amniotic cavity (MIAC) misc pre-B cell colony-enhancing factor (PBEF) misc preterm labor misc preterm prelabor rupture of membranes (preterm PROM) misc visfatin Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition |
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misc Microbial invasion of the amniotic cavity (MIAC) misc pre-B cell colony-enhancing factor (PBEF) misc preterm labor misc preterm prelabor rupture of membranes (preterm PROM) misc visfatin |
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misc Microbial invasion of the amniotic cavity (MIAC) misc pre-B cell colony-enhancing factor (PBEF) misc preterm labor misc preterm prelabor rupture of membranes (preterm PROM) misc visfatin |
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Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition |
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Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition |
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10.1515/JPM.2008.084 |
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visfatin/pre-b cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition |
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Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition |
| abstract |
Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. ©2008 by Walter de Gruyter Berlin New York |
| abstractGer |
Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. ©2008 by Walter de Gruyter Berlin New York |
| abstract_unstemmed |
Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection. ©2008 by Walter de Gruyter Berlin New York |
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Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition |
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Mazaki-Tovi, Shali Romero, Roberto Kusanovic, Juan Pedro Erez, Offer Gotsch, Francesca Mittal, Pooja Than, Nandor Gabor Nhan-Chang, Chia-Lang Hamill, Neil Vaisbuch, Edi Chaiworapongsa, Tinnakorn Edwin, Samuel S. Nien, Jyh Kae Gomez, Ricardo Espinoza, Jimmy Kendal-Wright, Claire Hassan, Sonia S. Bryant-Greenwood, Gillian |
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Mazaki-Tovi, Shali Romero, Roberto Kusanovic, Juan Pedro Erez, Offer Gotsch, Francesca Mittal, Pooja Than, Nandor Gabor Nhan-Chang, Chia-Lang Hamill, Neil Vaisbuch, Edi Chaiworapongsa, Tinnakorn Edwin, Samuel S. Nien, Jyh Kae Gomez, Ricardo Espinoza, Jimmy Kendal-Wright, Claire Hassan, Sonia S. Bryant-Greenwood, Gillian |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">NLEJ247143537</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230506082210.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220814s2008 xx |||||o 00| ||und c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1515/JPM.2008.084</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">artikel_Grundlieferung.pp</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)NLEJ247143537</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture of membranes: an association with subclinical intrauterine infection in preterm parturition</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="b">Walter de Gruyter</subfield><subfield code="c">2008 2008</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">©2008 by Walter de Gruyter Berlin New York</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective: Visfatin, a novel adipokine originally discovered as a pre-B-cell colony enhancing factor, is expressed by amniotic epithelium, cytotrophoblast, and decidua and is over-expressed when fetal membranes are exposed to mechanical stress and/or pro-inflammatory stimuli. Visfatin expression by fetal membranes is dramatically up-regulated after normal spontaneous labor. The aims of this study were to determine if visfatin is detectable in amniotic fluid (AF) and whether its concentration changes with gestational age, spontaneous labor, preterm prelabor rupture of membranes (preterm PROM) and in the presence of microbial invasion of the amniotic cavity (MIAC). Methods: In this cross-sectional study, visfatin concentration in AF was determined in patients in the following groups: 1) mid-trimester (n=75); 2) term not in labor (n=27); 3) term in spontaneous labor (n=51); 4) patients with preterm labor with intact membranes (PTL) without MIAC who delivered at term (n=35); 5) patients with PTL without MIAC who delivered preterm (n=52); 6) patients with PTL with MIAC (n=25); 7) women with preterm PROM without MIAC (n=26); and 8) women with preterm PROM with MIAC (n=26). Non-parametric statistics were used for analysis. Results: 1) The median AF concentration of visfatin was significantly higher in patients at term than in mid-trimester; 2) Among women with PTL who delivered preterm, the median visfatin concentration was significantly higher in patients with MIAC than those without MIAC; 3) Similarly, patients with PTL and MIAC had a higher median AF visfatin concentration than those with PTL who delivered at term; 4) Among women with preterm PROM, the median AF visfatin concentration was significantly higher in patients with MIAC than those without MIAC. Conclusions: 1) Visfatin is a physiologic constituent of AF; 2) The concentration of AF visfatin increases with advancing gestational age; 3) AF visfatin concentration is elevated in patients with MIAC, regardless of the membrane status, suggesting that visfatin participates in the host response against infection.</subfield></datafield><datafield tag="533" ind1=" " ind2=" "><subfield code="f">Walter de Gruyter Online Zeitschriften</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbial invasion of the amniotic cavity (MIAC)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">pre-B cell colony-enhancing factor (PBEF)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">preterm labor</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">preterm prelabor rupture of membranes (preterm PROM)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield 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code="a">Nhan-Chang, Chia-Lang</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hamill, Neil</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Vaisbuch, Edi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chaiworapongsa, Tinnakorn</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Edwin, Samuel S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nien, Jyh Kae</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gomez, Ricardo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Espinoza, Jimmy</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kendal-Wright, Claire</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hassan, Sonia S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bryant-Greenwood, Gillian</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of perinatal medicine</subfield><subfield code="d">Berlin [u.a.] : de Gruyter, 1973</subfield><subfield code="g">36(2008 2008), 6 vom: 04 04., Seite 485-496</subfield><subfield code="w">(DE-627)NLEJ248236229</subfield><subfield code="w">(DE-600)1467968-1</subfield><subfield code="x">16193997</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:36</subfield><subfield code="g">year:2008 2008</subfield><subfield code="g">number:6</subfield><subfield code="g">day:04 04</subfield><subfield code="g">month:07</subfield><subfield code="g">pages:485-496</subfield><subfield code="g">extent:12</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1515/JPM.2008.084</subfield><subfield code="z">Deutschlandweit zugänglich</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-1-DGR</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_NL_ARTICLE</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">36</subfield><subfield code="j">2008 2008</subfield><subfield code="e">6</subfield><subfield code="b">04 04</subfield><subfield code="c">07 07</subfield><subfield code="h">485-496</subfield><subfield code="g">12</subfield></datafield></record></collection>
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