The role of setting for ketamine abuse: clinical and preclinical evidence
Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug. This is particularly evident in the case of ‘club drugs...
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E-Artikel |
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De Gruyter ; 2012 |
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12 |
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Walter de Gruyter Online Zeitschriften |
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Enthalten in: Reviews in the neurosciences - Berlin : de Gruyter, 1987, 23(2012), 5-6 vom: 17. Nov., Seite 769-780 |
| Übergeordnetes Werk: |
volume:23 ; year:2012 ; number:5-6 ; day:17 ; month:11 ; pages:769-780 ; extent:12 |
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| DOI / URN: |
10.1515/revneuro-2012-0078 |
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NLEJ247535648 |
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10.1515/revneuro-2012-0078 doi artikel_Grundlieferung.pp (DE-627)NLEJ247535648 DE-627 ger DE-627 rakwb The role of setting for ketamine abuse: clinical and preclinical evidence De Gruyter 2012 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug. This is particularly evident in the case of ‘club drugs’, such as ketamine. Although the number of ketamine abusers is relatively small in the general population, it is quite substantial in some settings. In particular, ketamine abuse is almost exclusively limited to clubs and large music parties, which suggests a major role of context in modulating the reward effects of this drug. This review focuses on recent preclinical and clinical findings, including previously unpublished data, that provide evidence that, even under controlled conditions, ketamine reward is a function of the setting of drug taking. Walter de Gruyter Online Zeitschriften cocaine context drug abuse drug addiction environment hallucinogens heroin ketamine opiates psychostimulants setting De Luca, Maria Teresa oth Meringolo, Maria oth Spagnolo, Primavera Alessandra oth Badiani, Aldo oth Enthalten in Reviews in the neurosciences Berlin : de Gruyter, 1987 23(2012), 5-6 vom: 17. Nov., Seite 769-780 (DE-627)NLEJ248236709 (DE-600)2598365-9 2191-0200 nnns volume:23 year:2012 number:5-6 day:17 month:11 pages:769-780 extent:12 https://doi.org/10.1515/revneuro-2012-0078 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 23 2012 5-6 17 11 769-780 12 |
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10.1515/revneuro-2012-0078 doi artikel_Grundlieferung.pp (DE-627)NLEJ247535648 DE-627 ger DE-627 rakwb The role of setting for ketamine abuse: clinical and preclinical evidence De Gruyter 2012 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug. This is particularly evident in the case of ‘club drugs’, such as ketamine. Although the number of ketamine abusers is relatively small in the general population, it is quite substantial in some settings. In particular, ketamine abuse is almost exclusively limited to clubs and large music parties, which suggests a major role of context in modulating the reward effects of this drug. This review focuses on recent preclinical and clinical findings, including previously unpublished data, that provide evidence that, even under controlled conditions, ketamine reward is a function of the setting of drug taking. Walter de Gruyter Online Zeitschriften cocaine context drug abuse drug addiction environment hallucinogens heroin ketamine opiates psychostimulants setting De Luca, Maria Teresa oth Meringolo, Maria oth Spagnolo, Primavera Alessandra oth Badiani, Aldo oth Enthalten in Reviews in the neurosciences Berlin : de Gruyter, 1987 23(2012), 5-6 vom: 17. Nov., Seite 769-780 (DE-627)NLEJ248236709 (DE-600)2598365-9 2191-0200 nnns volume:23 year:2012 number:5-6 day:17 month:11 pages:769-780 extent:12 https://doi.org/10.1515/revneuro-2012-0078 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 23 2012 5-6 17 11 769-780 12 |
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10.1515/revneuro-2012-0078 doi artikel_Grundlieferung.pp (DE-627)NLEJ247535648 DE-627 ger DE-627 rakwb The role of setting for ketamine abuse: clinical and preclinical evidence De Gruyter 2012 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug. This is particularly evident in the case of ‘club drugs’, such as ketamine. Although the number of ketamine abusers is relatively small in the general population, it is quite substantial in some settings. In particular, ketamine abuse is almost exclusively limited to clubs and large music parties, which suggests a major role of context in modulating the reward effects of this drug. This review focuses on recent preclinical and clinical findings, including previously unpublished data, that provide evidence that, even under controlled conditions, ketamine reward is a function of the setting of drug taking. Walter de Gruyter Online Zeitschriften cocaine context drug abuse drug addiction environment hallucinogens heroin ketamine opiates psychostimulants setting De Luca, Maria Teresa oth Meringolo, Maria oth Spagnolo, Primavera Alessandra oth Badiani, Aldo oth Enthalten in Reviews in the neurosciences Berlin : de Gruyter, 1987 23(2012), 5-6 vom: 17. Nov., Seite 769-780 (DE-627)NLEJ248236709 (DE-600)2598365-9 2191-0200 nnns volume:23 year:2012 number:5-6 day:17 month:11 pages:769-780 extent:12 https://doi.org/10.1515/revneuro-2012-0078 Deutschlandweit zugänglich GBV_USEFLAG_U ZDB-1-DGR GBV_NL_ARTICLE AR 23 2012 5-6 17 11 769-780 12 |
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Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug. This is particularly evident in the case of ‘club drugs’, such as ketamine. Although the number of ketamine abusers is relatively small in the general population, it is quite substantial in some settings. In particular, ketamine abuse is almost exclusively limited to clubs and large music parties, which suggests a major role of context in modulating the reward effects of this drug. This review focuses on recent preclinical and clinical findings, including previously unpublished data, that provide evidence that, even under controlled conditions, ketamine reward is a function of the setting of drug taking. |
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Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug. This is particularly evident in the case of ‘club drugs’, such as ketamine. Although the number of ketamine abusers is relatively small in the general population, it is quite substantial in some settings. In particular, ketamine abuse is almost exclusively limited to clubs and large music parties, which suggests a major role of context in modulating the reward effects of this drug. This review focuses on recent preclinical and clinical findings, including previously unpublished data, that provide evidence that, even under controlled conditions, ketamine reward is a function of the setting of drug taking. |
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Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug. This is particularly evident in the case of ‘club drugs’, such as ketamine. Although the number of ketamine abusers is relatively small in the general population, it is quite substantial in some settings. In particular, ketamine abuse is almost exclusively limited to clubs and large music parties, which suggests a major role of context in modulating the reward effects of this drug. This review focuses on recent preclinical and clinical findings, including previously unpublished data, that provide evidence that, even under controlled conditions, ketamine reward is a function of the setting of drug taking. |
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