Leuko-araiosis and cerebral perfusion in normal aging
To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporti...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Kawamura, J. [verfasserIn] Terayama, Y. [verfasserIn] Takashima, S. [verfasserIn] Obara, K. [verfasserIn] Pavol, M. A. [verfasserIn] Meyer, John [verfasserIn] Mortel, K. F. [verfasserIn] Weathers, S. [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2011 |
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| Übergeordnetes Werk: |
Enthalten in: Experimental aging research - London [u.a.] : Taylor & Francis, 1975, 19(1993), 3 vom: 01. Juli, Seite 225-240 |
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| Übergeordnetes Werk: |
number:3 ; volume:19 ; year:1993 ; month:07 ; day:01 ; pages:225-240 |
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| DOI / URN: |
10.1080/03610739308253935 |
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NLEJ252986520 |
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| 520 | |a To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships | ||
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| 700 | 1 | |a Weathers, S. |e verfasserin |4 aut | |
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10.1080/03610739308253935 doi (DE-627)NLEJ252986520 (TFO)782580465 DE-627 ger DE-627 rda eng Kawamura, J. verfasserin aut Leuko-araiosis and cerebral perfusion in normal aging 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships Terayama, Y. verfasserin aut Takashima, S. verfasserin aut Obara, K. verfasserin aut Pavol, M. A. verfasserin aut Meyer, John verfasserin aut Mortel, K. F. verfasserin aut Weathers, S. verfasserin aut Enthalten in Experimental aging research London [u.a.] : Taylor & Francis, 1975 19(1993), 3 vom: 01. Juli, Seite 225-240 Online-Ressource (DE-627)NLEJ252983483 (DE-600)1482552-1 (DE-576)088704491 1096-4657 nnns number:3 volume:19 year:1993 month:07 day:01 pages:225-240 https://www.tib.eu/de/suchen/id/tandf%3A9025879416c88d4bd4418968f9d910ddbeb2c433 Digitalisierung Deutschlandweit zugänglich ZDB-1-TFO GBV_NL_ARTICLE AR 3 19 1993 7 01 225-240 |
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10.1080/03610739308253935 doi (DE-627)NLEJ252986520 (TFO)782580465 DE-627 ger DE-627 rda eng Kawamura, J. verfasserin aut Leuko-araiosis and cerebral perfusion in normal aging 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships Terayama, Y. verfasserin aut Takashima, S. verfasserin aut Obara, K. verfasserin aut Pavol, M. A. verfasserin aut Meyer, John verfasserin aut Mortel, K. F. verfasserin aut Weathers, S. verfasserin aut Enthalten in Experimental aging research London [u.a.] : Taylor & Francis, 1975 19(1993), 3 vom: 01. Juli, Seite 225-240 Online-Ressource (DE-627)NLEJ252983483 (DE-600)1482552-1 (DE-576)088704491 1096-4657 nnns number:3 volume:19 year:1993 month:07 day:01 pages:225-240 https://www.tib.eu/de/suchen/id/tandf%3A9025879416c88d4bd4418968f9d910ddbeb2c433 Digitalisierung Deutschlandweit zugänglich ZDB-1-TFO GBV_NL_ARTICLE AR 3 19 1993 7 01 225-240 |
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10.1080/03610739308253935 doi (DE-627)NLEJ252986520 (TFO)782580465 DE-627 ger DE-627 rda eng Kawamura, J. verfasserin aut Leuko-araiosis and cerebral perfusion in normal aging 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships Terayama, Y. verfasserin aut Takashima, S. verfasserin aut Obara, K. verfasserin aut Pavol, M. A. verfasserin aut Meyer, John verfasserin aut Mortel, K. F. verfasserin aut Weathers, S. verfasserin aut Enthalten in Experimental aging research London [u.a.] : Taylor & Francis, 1975 19(1993), 3 vom: 01. Juli, Seite 225-240 Online-Ressource (DE-627)NLEJ252983483 (DE-600)1482552-1 (DE-576)088704491 1096-4657 nnns number:3 volume:19 year:1993 month:07 day:01 pages:225-240 https://www.tib.eu/de/suchen/id/tandf%3A9025879416c88d4bd4418968f9d910ddbeb2c433 Digitalisierung Deutschlandweit zugänglich ZDB-1-TFO GBV_NL_ARTICLE AR 3 19 1993 7 01 225-240 |
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10.1080/03610739308253935 doi (DE-627)NLEJ252986520 (TFO)782580465 DE-627 ger DE-627 rda eng Kawamura, J. verfasserin aut Leuko-araiosis and cerebral perfusion in normal aging 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships Terayama, Y. verfasserin aut Takashima, S. verfasserin aut Obara, K. verfasserin aut Pavol, M. A. verfasserin aut Meyer, John verfasserin aut Mortel, K. F. verfasserin aut Weathers, S. verfasserin aut Enthalten in Experimental aging research London [u.a.] : Taylor & Francis, 1975 19(1993), 3 vom: 01. Juli, Seite 225-240 Online-Ressource (DE-627)NLEJ252983483 (DE-600)1482552-1 (DE-576)088704491 1096-4657 nnns number:3 volume:19 year:1993 month:07 day:01 pages:225-240 https://www.tib.eu/de/suchen/id/tandf%3A9025879416c88d4bd4418968f9d910ddbeb2c433 Digitalisierung Deutschlandweit zugänglich ZDB-1-TFO GBV_NL_ARTICLE AR 3 19 1993 7 01 225-240 |
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10.1080/03610739308253935 doi (DE-627)NLEJ252986520 (TFO)782580465 DE-627 ger DE-627 rda eng Kawamura, J. verfasserin aut Leuko-araiosis and cerebral perfusion in normal aging 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships Terayama, Y. verfasserin aut Takashima, S. verfasserin aut Obara, K. verfasserin aut Pavol, M. A. verfasserin aut Meyer, John verfasserin aut Mortel, K. F. verfasserin aut Weathers, S. verfasserin aut Enthalten in Experimental aging research London [u.a.] : Taylor & Francis, 1975 19(1993), 3 vom: 01. Juli, Seite 225-240 Online-Ressource (DE-627)NLEJ252983483 (DE-600)1482552-1 (DE-576)088704491 1096-4657 nnns number:3 volume:19 year:1993 month:07 day:01 pages:225-240 https://www.tib.eu/de/suchen/id/tandf%3A9025879416c88d4bd4418968f9d910ddbeb2c433 Digitalisierung Deutschlandweit zugänglich ZDB-1-TFO GBV_NL_ARTICLE AR 3 19 1993 7 01 225-240 |
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Leuko-araiosis and cerebral perfusion in normal aging |
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To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships |
| abstractGer |
To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships |
| abstract_unstemmed |
To clarify the incidence, age relationships and pathogenesis of white matter lesions of unknown origin (leuko-araiosis) detected by neuroimaging among normal elderly volunteers, we measured the severity of leuko-araiosis using computerized tomographic (CT) densitometry among 42 healthy self-supporting men and women of different ages, all with normal neurological and cognitive test performance. Results were correlated with local cerebral perfusion using xenon-contrasted CT. The 42 volunteers, who are followed in this laboratory for studies of normal aging, were divided into two groups in order to determine aging effects by an extremes design. One group consisted of 19 adults below age 60 (M = 53.3, SD = 6.0). The index group comprised 23 individuals all over the age of 60 (M = 71.6, SD = 8.7). Leukoaraiosis around the anterior horns of the lateral ventricles (frontal leuko-araiosis) was more severe (p < .01) among the older group, however, occipital leuko-araiosis did not significantly differ between older and younger groups. Cerebral perfusion in frontal, temporal, and parietal cortex was decreased among older compared with younger volunteers (ps < .001, .01, and .05, respectively). Multiple regression analyses disclosed significant and direct relationships |
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Leuko-araiosis and cerebral perfusion in normal aging |
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Terayama, Y. Takashima, S. Obara, K. Pavol, M. A. Meyer, John Mortel, K. F. Weathers, S. |
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Terayama, Y. Takashima, S. Obara, K. Pavol, M. A. Meyer, John Mortel, K. F. Weathers, S. |
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